(85 nodes) Regulation of peptide hormone secretion network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_016819	Uncharacterized protein. (184 aa)
	ASZ78_009595	Pannexin_like domain-containing protein. (810 aa)
	ASZ78_014358	tRNA-binding domain-containing protein. (413 aa)
	ASZ78_015318	Uncharacterized protein. (142 aa)
	ASZ78_014364	Uncharacterized protein. (318 aa)
	ASZ78_000423	Uncharacterized protein. (125 aa)
	ASZ78_003329	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (490 aa)
	ASZ78_016656	Uncharacterized protein. (597 aa)
	ASZ78_016657	NR LBD domain-containing protein. (103 aa)
	ASZ78_015201	Uncharacterized protein. (194 aa)
	ASZ78_004707	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	ASZ78_016739	AMP-binding domain-containing protein. (688 aa)
	ASZ78_005701	Uncharacterized protein. (2862 aa)
	ASZ78_011580	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (175 aa)
	ASZ78_012997	GLUCAGON domain-containing protein. (172 aa)
	ASZ78_004252	Uncharacterized protein. (335 aa)
	ASZ78_000641	ILEI domain-containing protein. (218 aa)
	ASZ78_016057	Uncharacterized protein. (110 aa)
	ASZ78_011779	WD_REPEATS_REGION domain-containing protein. (395 aa)
	ASZ78_015054	TGF_BETA_2 domain-containing protein. (392 aa)
	ASZ78_005293	Uncharacterized protein. (490 aa)
	ASZ78_009793	Uncharacterized protein. (292 aa)
	ASZ78_008693	Deacetylase sirtuin-type domain-containing protein. (317 aa)
	ASZ78_004755	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1231 aa)
	ASZ78_005946	C2H2-type domain-containing protein. (297 aa)
	ASZ78_002978	Uncharacterized protein. (2291 aa)
	ASZ78_002057	PDZ domain-containing protein. (211 aa)
	ASZ78_003651	G_PROTEIN_RECEP_F2_3 domain-containing protein. (189 aa)
	ASZ78_008987	Uncharacterized protein. (495 aa)
	ASZ78_008912	GLUCAGON domain-containing protein. (167 aa)
	ASZ78_007588	CRF domain-containing protein. (108 aa)
	ASZ78_004912	zf-RING_14 domain-containing protein. (198 aa)
	ASZ78_014501	Ig-like domain-containing protein. (560 aa)
	ASZ78_010507	Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (384 aa)
	ASZ78_013989	RFX-type winged-helix domain-containing protein. (801 aa)
	ASZ78_001717	Tyrosine-protein kinase. (507 aa)
	ASZ78_006316	Deacetylase sirtuin-type domain-containing protein. (359 aa)
	ASZ78_014411	Uncharacterized protein. (675 aa)
	ASZ78_009420	Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (327 aa)
	ASZ78_015025	Ion_trans domain-containing protein; Belongs to the potassium channel family. (647 aa)
	ASZ78_016821	Signal peptidase complex catalytic subunit SEC11. (212 aa)
	ASZ78_014415	Uncharacterized protein. (408 aa)
	ASZ78_015583	Uncharacterized protein. (81 aa)
	ASZ78_015584	GLUCAGON domain-containing protein. (104 aa)
	ASZ78_011070	NR LBD domain-containing protein. (262 aa)
	ASZ78_001182	Uncharacterized protein. (690 aa)
	ASZ78_003244	BTB domain-containing protein. (214 aa)
	ASZ78_009311	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (126 aa)
	ASZ78_016529	Nitric oxide synthase; Produces nitric oxide (NO); Belongs to the complex I LYR family. (1248 aa)
	ASZ78_012615	Uncharacterized protein. (1089 aa)
	ASZ78_012616	Uncharacterized protein. (217 aa)
	ASZ78_017026	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1368 aa)
	ASZ78_010151	Uncharacterized protein. (566 aa)
	ASZ78_005992	Uncharacterized protein. (714 aa)
	ASZ78_002445	ABC transmembrane type-1 domain-containing protein. (480 aa)
	ASZ78_003611	Uncharacterized protein. (1335 aa)
	ASZ78_003628	Uncharacterized protein. (1379 aa)
	ASZ78_012357	Uncharacterized protein. (597 aa)
	ASZ78_007646	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (452 aa)
	ASZ78_002473	Uncharacterized protein. (893 aa)
	ASZ78_014046	Deacetylase sirtuin-type domain-containing protein. (198 aa)
	ASZ78_011879	SNF2_N domain-containing protein. (183 aa)
	ASZ78_009235	Homeobox domain-containing protein. (231 aa)
	ASZ78_003581	Zn_dep_PLPC domain-containing protein. (661 aa)
	ASZ78_005305	G_PROTEIN_RECEP_F1_2 domain-containing protein. (229 aa)
	ASZ78_005304	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (232 aa)
	ASZ78_006756	Uncharacterized protein. (359 aa)
	ASZ78_009333	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (318 aa)
	ASZ78_011846	Uncharacterized protein. (1066 aa)
	ASZ78_011845	Uncharacterized protein. (397 aa)
	ASZ78_014554	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (398 aa)
	ASZ78_000283	Uncharacterized protein. (660 aa)
	ASZ78_013014	C2 domain-containing protein. (141 aa)
	ASZ78_005841	G_PROTEIN_RECEP_F1_2 domain-containing protein. (472 aa)
	ASZ78_013012	C2 domain-containing protein. (312 aa)
	ASZ78_014318	Uncharacterized protein. (272 aa)
	ASZ78_007115	Uncharacterized protein; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (117 aa)
	ASZ78_015487	Uncharacterized protein. (337 aa)
	ASZ78_014332	Motilin_assoc domain-containing protein. (81 aa)
	ASZ78_007964	C-C motif chemokine. (91 aa)
	ASZ78_015158	Uncharacterized protein. (370 aa)
	ASZ78_008514	Signal peptidase I. (275 aa)
	ASZ78_008298	Uncharacterized protein. (280 aa)
	ASZ78_014310	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (596 aa)
	ASZ78_013592	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily. (84 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_001182	ASZ78_002445	A0A226MY05	A0A226MTD3	Uncharacterized protein.	ABC transmembrane type-1 domain-containing protein.	0.410
ASZ78_001182	ASZ78_007588	A0A226MY05	A0A226N7L4	Uncharacterized protein.	CRF domain-containing protein.	0.491
ASZ78_001182	ASZ78_011845	A0A226MY05	A0A226MIK9	Uncharacterized protein.	Uncharacterized protein.	0.536
ASZ78_001182	ASZ78_011846	A0A226MY05	A0A226MIJ3	Uncharacterized protein.	Uncharacterized protein.	0.410
ASZ78_001182	ASZ78_013989	A0A226MY05	A0A226N2Z9	Uncharacterized protein.	RFX-type winged-helix domain-containing protein.	0.524
ASZ78_001717	ASZ78_008298	A0A226N2X0	A0A226MNA1	Tyrosine-protein kinase.	Uncharacterized protein.	0.465
ASZ78_002057	ASZ78_002445	A0A226N9G2	A0A226MTD3	PDZ domain-containing protein.	ABC transmembrane type-1 domain-containing protein.	0.406
ASZ78_002057	ASZ78_004912	A0A226N9G2	A0A226N4R2	PDZ domain-containing protein.	zf-RING_14 domain-containing protein.	0.884
ASZ78_002057	ASZ78_011580	A0A226N9G2	A0A226NFS4	PDZ domain-containing protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.601
ASZ78_002057	ASZ78_011846	A0A226N9G2	A0A226MIJ3	PDZ domain-containing protein.	Uncharacterized protein.	0.406
ASZ78_002057	ASZ78_015318	A0A226N9G2	A0A226NLW9	PDZ domain-containing protein.	Uncharacterized protein.	0.655
ASZ78_002057	ASZ78_017026	A0A226N9G2	A0A226MNW5	PDZ domain-containing protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.508
ASZ78_002445	ASZ78_001182	A0A226MTD3	A0A226MY05	ABC transmembrane type-1 domain-containing protein.	Uncharacterized protein.	0.410
ASZ78_002445	ASZ78_002057	A0A226MTD3	A0A226N9G2	ABC transmembrane type-1 domain-containing protein.	PDZ domain-containing protein.	0.406
ASZ78_002445	ASZ78_004912	A0A226MTD3	A0A226N4R2	ABC transmembrane type-1 domain-containing protein.	zf-RING_14 domain-containing protein.	0.482
ASZ78_002445	ASZ78_011845	A0A226MTD3	A0A226MIK9	ABC transmembrane type-1 domain-containing protein.	Uncharacterized protein.	0.985
ASZ78_003244	ASZ78_015025	A0A226MXW1	A0A226N0P5	BTB domain-containing protein.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.558
ASZ78_003329	ASZ78_006316	A0A226NL26	A0A226N2B5	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Deacetylase sirtuin-type domain-containing protein.	0.645
ASZ78_003329	ASZ78_008693	A0A226NL26	A0A226NAU0	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Deacetylase sirtuin-type domain-containing protein.	0.765
ASZ78_003329	ASZ78_012357	A0A226NL26	A0A226MU12	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Uncharacterized protein.	0.528