(43 nodes) Positive regulation of cold-induced thermogenesis network (Callipepla squamata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_009372	Ribosomal_L7Ae domain-containing protein. (159 aa)
	ASZ78_009530	DOMON domain-containing protein. (672 aa)
	ASZ78_000827	TPR_REGION domain-containing protein. (1045 aa)
	ASZ78_004276	Uncharacterized protein. (163 aa)
	ASZ78_005305	G_PROTEIN_RECEP_F1_2 domain-containing protein. (229 aa)
	ASZ78_017087	CCAAT/enhancer-binding protein. (279 aa)
	ASZ78_004040	Uncharacterized protein. (123 aa)
	ASZ78_013195	RRM domain-containing protein. (983 aa)
	ASZ78_001069	Uncharacterized protein. (111 aa)
	ASZ78_014049	Uncharacterized protein. (144 aa)
	ASZ78_014332	Motilin_assoc domain-containing protein. (81 aa)
	ASZ78_009821	Uncharacterized protein. (1103 aa)
	ASZ78_009820	Uncharacterized protein. (224 aa)
	ASZ78_007253	Uncharacterized protein. (652 aa)
	ASZ78_000153	AMPKBI domain-containing protein. (293 aa)
	ASZ78_013284	G_PROTEIN_RECEP_F1_2 domain-containing protein. (337 aa)
	ASZ78_003627	C1q domain-containing protein. (270 aa)
	ASZ78_007652	Interleukin-18. (196 aa)
	ASZ78_004471	ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (756 aa)
	ASZ78_007066	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (126 aa)
	ASZ78_011065	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (829 aa)
	ASZ78_016539	RRM domain-containing protein. (814 aa)
	ASZ78_006074	Alkaline phosphatase. (525 aa)
	ASZ78_011164	Uncharacterized protein. (742 aa)
	ASZ78_006316	Deacetylase sirtuin-type domain-containing protein. (359 aa)
	ASZ78_006715	G_PROTEIN_RECEP_F1_2 domain-containing protein. (424 aa)
	ASZ78_003880	Uncharacterized protein. (3992 aa)
	ASZ78_010813	G_PROTEIN_RECEP_F1_2 domain-containing protein. (545 aa)
	ASZ78_003099	ALMS_motif domain-containing protein. (2869 aa)
	ASZ78_016798	LNS2 domain-containing protein. (1008 aa)
	ASZ78_014210	Homeobox domain-containing protein. (237 aa)
	ASZ78_009937	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (755 aa)
	ASZ78_016011	Peptidase_M48 domain-containing protein. (310 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (737 aa)
	ASZ78_004011	Uncharacterized protein. (645 aa)
	ASZ78_003724	Uncharacterized protein. (467 aa)
	ASZ78_013890	Uncharacterized protein. (1061 aa)
	ASZ78_015884	Uncharacterized protein. (376 aa)
	ASZ78_014364	Uncharacterized protein. (318 aa)
	ASZ78_002170	Uncharacterized protein. (126 aa)
	ASZ78_015705	Uncharacterized protein. (389 aa)
	ASZ78_007225	Uncharacterized protein. (324 aa)
	ASZ78_004873	Uncharacterized protein. (339 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000153	ASZ78_016539	A0A226MR61	A0A226MYN1	AMPKBI domain-containing protein.	RRM domain-containing protein.	0.811
ASZ78_000827	ASZ78_001069	A0A226MF50	A0A226MIW6	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.467
ASZ78_000827	ASZ78_016539	A0A226MF50	A0A226MYN1	TPR_REGION domain-containing protein.	RRM domain-containing protein.	0.809
ASZ78_001069	ASZ78_000827	A0A226MIW6	A0A226MF50	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.467
ASZ78_001069	ASZ78_016539	A0A226MIW6	A0A226MYN1	Uncharacterized protein.	RRM domain-containing protein.	0.647
ASZ78_003627	ASZ78_007225	A0A226MU44	A0A226MCX7	C1q domain-containing protein.	Uncharacterized protein.	0.988
ASZ78_003627	ASZ78_013890	A0A226MU44	A0A226NGJ0	C1q domain-containing protein.	Uncharacterized protein.	0.555
ASZ78_003627	ASZ78_014332	A0A226MU44	A0A226ML72	C1q domain-containing protein.	Motilin_assoc domain-containing protein.	0.560
ASZ78_003627	ASZ78_015705	A0A226MU44	A0A226NNF8	C1q domain-containing protein.	Uncharacterized protein.	0.553
ASZ78_003627	ASZ78_015884	A0A226MU44	A0A226NHT4	C1q domain-containing protein.	Uncharacterized protein.	0.988
ASZ78_003627	ASZ78_016539	A0A226MU44	A0A226MYN1	C1q domain-containing protein.	RRM domain-containing protein.	0.571
ASZ78_003627	ASZ78_017087	A0A226MU44	A0A226MH09	C1q domain-containing protein.	CCAAT/enhancer-binding protein.	0.745
ASZ78_003724	ASZ78_014364	A0A226NFE8	A0A226NLM9	Uncharacterized protein.	Uncharacterized protein.	0.518
ASZ78_003880	ASZ78_007253	A0A226N4U1	A0A226MP07	Uncharacterized protein.	Uncharacterized protein.	0.919
ASZ78_004011	ASZ78_004276	A0A226NF63	A0A226MGJ1	Uncharacterized protein.	Uncharacterized protein.	0.839
ASZ78_004011	ASZ78_009820	A0A226NF63	A0A226MMT8	Uncharacterized protein.	Uncharacterized protein.	0.839
ASZ78_004011	ASZ78_009821	A0A226NF63	A0A226MMR0	Uncharacterized protein.	Uncharacterized protein.	0.839
ASZ78_004011	ASZ78_011065	A0A226NF63	A0A226MY33	Uncharacterized protein.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.936
ASZ78_004276	ASZ78_004011	A0A226MGJ1	A0A226NF63	Uncharacterized protein.	Uncharacterized protein.	0.839
ASZ78_004276	ASZ78_009821	A0A226MGJ1	A0A226MMR0	Uncharacterized protein.	Uncharacterized protein.	0.555