(84 nodes) Response to ketone network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_007248	HATPase_c domain-containing protein. (609 aa)
	ASZ78_011876	Uncharacterized protein. (94 aa)
	ASZ78_001194	Uncharacterized protein. (140 aa)
	ASZ78_009804	Uncharacterized protein; Belongs to the AKAP95 family. (458 aa)
	ASZ78_000081	TGF_BETA_2 domain-containing protein. (368 aa)
	ASZ78_014932	RUN domain-containing protein. (561 aa)
	ASZ78_009133	Uncharacterized protein. (196 aa)
	ASZ78_009132	Uncharacterized protein. (507 aa)
	ASZ78_002817	Homeobox domain-containing protein. (195 aa)
	ASZ78_013264	NR LBD domain-containing protein. (122 aa)
	ASZ78_013262	NR LBD domain-containing protein. (216 aa)
	ASZ78_002298	TGF_BETA_2 domain-containing protein. (199 aa)
	ASZ78_009175	TGF_BETA_2 domain-containing protein. (478 aa)
	ASZ78_003571	HTH La-type RNA-binding domain-containing protein. (1105 aa)
	ASZ78_015468	Uncharacterized protein. (315 aa)
	ASZ78_011722	Uncharacterized protein; Belongs to the cytochrome P450 family. (517 aa)
	ASZ78_009107	AdenylateSensor domain-containing protein. (301 aa)
	ASZ78_009108	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (474 aa)
	ASZ78_017026	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1368 aa)
	ASZ78_017030	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (229 aa)
	ASZ78_000547	Uncharacterized protein. (598 aa)
	ASZ78_011819	Uncharacterized protein. (179 aa)
	ASZ78_000233	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (859 aa)
	ASZ78_009114	AB hydrolase-1 domain-containing protein. (436 aa)
	ASZ78_012296	Uncharacterized protein. (808 aa)
	ASZ78_016856	Uncharacterized protein. (467 aa)
	ASZ78_013308	Uncharacterized protein. (442 aa)
	ASZ78_011854	Uncharacterized protein. (622 aa)
	ASZ78_004981	Inhibitor_Mig-6 domain-containing protein. (489 aa)
	ASZ78_004987	DJ-1_PfpI domain-containing protein. (189 aa)
	ASZ78_008097	G_PROTEIN_RECEP_F1_2 domain-containing protein. (364 aa)
	ASZ78_000960	BHLH domain-containing protein. (338 aa)
	ASZ78_001085	Homeobox domain-containing protein. (364 aa)
	ASZ78_001455	Uncharacterized protein. (159 aa)
	ASZ78_001452	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1138 aa)
	ASZ78_006085	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (479 aa)
	ASZ78_009725	TGF_BETA_2 domain-containing protein. (192 aa)
	ASZ78_013691	Uncharacterized protein. (1037 aa)
	ASZ78_004746	Uncharacterized protein. (48 aa)
	ASZ78_000262	Uncharacterized protein. (393 aa)
	ASZ78_013981	RWD domain-containing protein. (240 aa)
	ASZ78_013242	Uncharacterized protein. (355 aa)
	ASZ78_002624	Uncharacterized protein. (864 aa)
	ASZ78_006468	FERM domain-containing protein. (518 aa)
	ASZ78_000894	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (591 aa)
	ASZ78_006398	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	ASZ78_006478	Uncharacterized protein. (683 aa)
	ASZ78_016795	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1393 aa)
	ASZ78_002579	Uncharacterized protein. (365 aa)
	ASZ78_011216	Uncharacterized protein. (1085 aa)
	ASZ78_004140	Uncharacterized protein. (188 aa)
	ASZ78_006838	Uncharacterized protein. (685 aa)
	ASZ78_003652	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (143 aa)
	ASZ78_009914	SCY domain-containing protein. (84 aa)
	ASZ78_004755	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1231 aa)
	ASZ78_009969	Uncharacterized protein; Belongs to the peptidase C14A family. (391 aa)
	ASZ78_009968	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (191 aa)
	ASZ78_001689	G_PROTEIN_RECEP_F1_2 domain-containing protein. (322 aa)
	ASZ78_005944	Uncharacterized protein. (346 aa)
	ASZ78_016017	Non-specific serine/threonine protein kinase. (475 aa)
	ASZ78_008174	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (996 aa)
	ASZ78_000216	5'-3' exoribonuclease 1. (1636 aa)
	ASZ78_016277	Uncharacterized protein; Belongs to the 3-beta-HSD family. (331 aa)
	ASZ78_008401	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (455 aa)
	ASZ78_005072	Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
	ASZ78_015038	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (556 aa)
	ASZ78_015037	AC_N domain-containing protein. (91 aa)
	ASZ78_014616	Uncharacterized protein. (865 aa)
	ASZ78_015039	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (267 aa)
	ASZ78_011646	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (212 aa)
	ASZ78_011627	FAD-binding FR-type domain-containing protein. (385 aa)
	ASZ78_013068	Uncharacterized protein. (294 aa)
	ASZ78_003552	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	ASZ78_015876	Uncharacterized protein. (355 aa)
	ASZ78_002351	G_PROTEIN_RECEP_F1_2 domain-containing protein. (257 aa)
	ASZ78_006008	Uncharacterized protein; Belongs to the serpin family. (861 aa)
	ASZ78_005488	BH4_2 domain-containing protein. (229 aa)
	ASZ78_005462	BPI2 domain-containing protein. (447 aa)
	ASZ78_016657	NR LBD domain-containing protein. (103 aa)
	ASZ78_016656	Uncharacterized protein. (597 aa)
	ASZ78_008666	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (425 aa)
	ASZ78_002261	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (717 aa)
	ASZ78_002260	Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa)
	ASZ78_005374	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (377 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000081	ASZ78_000262	A0A226MD51	A0A226N1D9	TGF_BETA_2 domain-containing protein.	Uncharacterized protein.	0.426
ASZ78_000081	ASZ78_008666	A0A226MD51	A0A226NL83	TGF_BETA_2 domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.589
ASZ78_000216	ASZ78_015468	A0A226NBX3	A0A226ML28	5'-3' exoribonuclease 1.	Uncharacterized protein.	0.647
ASZ78_000233	ASZ78_006478	A0A226MQF8	A0A226N5Y7	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	Uncharacterized protein.	0.504
ASZ78_000233	ASZ78_007248	A0A226MQF8	A0A226MNK8	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	HATPase_c domain-containing protein.	0.542
ASZ78_000233	ASZ78_008401	A0A226MQF8	A0A226NCA0	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.699
ASZ78_000262	ASZ78_000081	A0A226N1D9	A0A226MD51	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.426
ASZ78_000262	ASZ78_002298	A0A226N1D9	A0A226MIE7	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.426
ASZ78_000262	ASZ78_003552	A0A226N1D9	A0A226NHF3	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.426
ASZ78_000262	ASZ78_005462	A0A226N1D9	A0A226NK36	Uncharacterized protein.	BPI2 domain-containing protein.	0.560
ASZ78_000262	ASZ78_006008	A0A226N1D9	A0A226NI85	Uncharacterized protein.	Uncharacterized protein; Belongs to the serpin family.	0.536
ASZ78_000262	ASZ78_009175	A0A226N1D9	A0A226MIY0	Uncharacterized protein.	TGF_BETA_2 domain-containing protein.	0.426
ASZ78_000262	ASZ78_011646	A0A226N1D9	A0A226NG67	Uncharacterized protein.	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.	0.560
ASZ78_000547	ASZ78_005488	A0A226MP91	A0A226NJC6	Uncharacterized protein.	BH4_2 domain-containing protein.	0.696
ASZ78_000547	ASZ78_009969	A0A226MP91	A0A226N9U8	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.480
ASZ78_000547	ASZ78_011627	A0A226MP91	A0A226NGB3	Uncharacterized protein.	FAD-binding FR-type domain-containing protein.	0.443
ASZ78_000547	ASZ78_013308	A0A226MP91	A0A226MVE9	Uncharacterized protein.	Uncharacterized protein.	0.827
ASZ78_000547	ASZ78_016856	A0A226MP91	A0A226MTU1	Uncharacterized protein.	Uncharacterized protein.	0.827
ASZ78_000894	ASZ78_001455	A0A226N5Y2	A0A226MZA9	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.703
ASZ78_000894	ASZ78_002579	A0A226N5Y2	A0A226N673	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein.	0.936