(102 nodes) Regulation of cysteine-type endopeptidase activity network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_014953	Uncharacterized protein; Belongs to the peptidase C14A family. (371 aa)
	ASZ78_013277	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	ASZ78_011281	Uncharacterized protein. (531 aa)
	ASZ78_006529	Uncharacterized protein. (166 aa)
	ASZ78_013743	Uncharacterized protein. (320 aa)
	ASZ78_013736	CARD domain-containing protein. (223 aa)
	ASZ78_002575	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (688 aa)
	ASZ78_006399	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (796 aa)
	ASZ78_008036	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (283 aa)
	ASZ78_008049	ANK_REP_REGION domain-containing protein. (1411 aa)
	ASZ78_010524	RING-type domain-containing protein. (335 aa)
	ASZ78_001724	Uncharacterized protein. (378 aa)
	ASZ78_007418	GRAM domain-containing protein. (579 aa)
	ASZ78_000277	Uncharacterized protein. (364 aa)
	ASZ78_000276	Uncharacterized protein. (522 aa)
	ASZ78_005901	Uncharacterized protein. (212 aa)
	ASZ78_016817	Uncharacterized protein. (795 aa)
	ASZ78_001144	Uncharacterized protein; Belongs to the peptidase C14A family. (1337 aa)
	ASZ78_001146	Uncharacterized protein; Belongs to the peptidase C14A family. (403 aa)
	ASZ78_000796	Uncharacterized protein. (163 aa)
	ASZ78_000813	USP domain-containing protein; Belongs to the peptidase C19 family. (1312 aa)
	ASZ78_008095	Uncharacterized protein. (780 aa)
	ASZ78_000960	BHLH domain-containing protein. (338 aa)
	ASZ78_016895	Protein kinase domain-containing protein. (983 aa)
	ASZ78_002473	Uncharacterized protein. (893 aa)
	ASZ78_016888	FABP domain-containing protein. (148 aa)
	ASZ78_007651	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (174 aa)
	ASZ78_016443	Uncharacterized protein. (551 aa)
	ASZ78_011802	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (268 aa)
	ASZ78_007044	RING-type domain-containing protein. (361 aa)
	ASZ78_010568	Uncharacterized protein. (689 aa)
	ASZ78_000547	Uncharacterized protein. (598 aa)
	ASZ78_002365	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (573 aa)
	ASZ78_003778	CARD domain-containing protein. (117 aa)
	ASZ78_008509	Uncharacterized protein. (606 aa)
	ASZ78_007965	I/LWEQ domain-containing protein. (928 aa)
	ASZ78_011422	Uncharacterized protein. (416 aa)
	ASZ78_016342	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa)
	ASZ78_016129	Uncharacterized protein. (1663 aa)
	ASZ78_015637	Uncharacterized protein. (139 aa)
	ASZ78_006254	Uncharacterized protein. (483 aa)
	ASZ78_005418	Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (180 aa)
	ASZ78_014554	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (398 aa)
	ASZ78_001638	Uncharacterized protein. (100 aa)
	ASZ78_005425	Uncharacterized protein. (395 aa)
	ASZ78_001311	Uncharacterized protein. (389 aa)
	ASZ78_001892	Deacetylase sirtuin-type domain-containing protein. (593 aa)
	ASZ78_006272	Asp_Arg_Hydrox domain-containing protein. (247 aa)
	ASZ78_006273	Uncharacterized protein. (78 aa)
	ASZ78_015109	Death domain-containing protein. (297 aa)
	ASZ78_006271	Asp-B-Hydro_N domain-containing protein. (170 aa)
	ASZ78_006274	Uncharacterized protein. (136 aa)
	ASZ78_012600	Bclx_interact domain-containing protein. (91 aa)
	ASZ78_002137	PDZ domain-containing protein. (309 aa)
	ASZ78_002817	Homeobox domain-containing protein. (195 aa)
	ASZ78_003165	Uncharacterized protein. (819 aa)
	ASZ78_005552	RING-type domain-containing protein. (279 aa)
	ASZ78_014577	PRA1 family protein. (188 aa)
	ASZ78_004707	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	ASZ78_010362	Uncharacterized protein. (90 aa)
	ASZ78_004700	DUF3677 domain-containing protein. (2215 aa)
	ASZ78_015854	Uncharacterized protein. (58 aa)
	ASZ78_005689	CARD domain-containing protein. (530 aa)
	ASZ78_013564	Uncharacterized protein. (671 aa)
	ASZ78_011896	Tyrosine-protein kinase. (305 aa)
	ASZ78_011580	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (175 aa)
	ASZ78_012987	Uncharacterized protein. (280 aa)
	ASZ78_004253	G_PROTEIN_RECEP_F1_2 domain-containing protein. (175 aa)
	ASZ78_012468	Uncharacterized protein. (299 aa)
	ASZ78_015446	Uncharacterized protein. (1071 aa)
	ASZ78_014622	Uncharacterized protein. (505 aa)
	ASZ78_014613	Uncharacterized protein. (882 aa)
	ASZ78_012850	Uncharacterized protein. (167 aa)
	ASZ78_001562	Non-specific serine/threonine protein kinase. (525 aa)
	ASZ78_005300	Uncharacterized protein. (997 aa)
	ASZ78_008337	CIDE-N domain-containing protein. (238 aa)
	ASZ78_007368	Uncharacterized protein. (405 aa)
	ASZ78_016022	FAD-binding PCMH-type domain-containing protein. (516 aa)
	ASZ78_016288	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa)
	ASZ78_008184	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (253 aa)
	ASZ78_014709	Uncharacterized protein. (431 aa)
	ASZ78_000147	Thioredoxin domain-containing protein. (258 aa)
	ASZ78_009961	Uncharacterized protein. (321 aa)
	ASZ78_002069	Uncharacterized protein. (151 aa)
	ASZ78_009969	Uncharacterized protein; Belongs to the peptidase C14A family. (391 aa)
	ASZ78_003652	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (143 aa)
	ASZ78_002047	RING-type domain-containing protein. (150 aa)
	ASZ78_002044	I/LWEQ domain-containing protein. (966 aa)
	ASZ78_006838	Uncharacterized protein. (685 aa)
	ASZ78_006828	PCI domain-containing protein. (352 aa)
	ASZ78_004524	Uncharacterized protein. (410 aa)
	ASZ78_002876	WD_REPEATS_REGION domain-containing protein. (514 aa)
	ASZ78_004872	Uncharacterized protein. (434 aa)
	ASZ78_012115	Uncharacterized protein. (54 aa)
	ASZ78_011692	Uncharacterized protein. (325 aa)
	ASZ78_004352	G_PROTEIN_RECEP_F1_2 domain-containing protein. (156 aa)
	ASZ78_000916	MYT1 domain-containing protein. (568 aa)
	ASZ78_008815	Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (400 aa)
	ASZ78_000917	MYT1 domain-containing protein. (376 aa)
	ASZ78_015312	Cystatin domain-containing protein. (165 aa)
	ASZ78_015318	Uncharacterized protein. (142 aa)
	ASZ78_011305	HP domain-containing protein. (750 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000147	ASZ78_002365	A0A226NAA5	A0A226MP69	Thioredoxin domain-containing protein.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.400
ASZ78_000147	ASZ78_003165	A0A226NAA5	A0A226MGH2	Thioredoxin domain-containing protein.	Uncharacterized protein.	0.607
ASZ78_000147	ASZ78_005425	A0A226NAA5	A0A226MIS4	Thioredoxin domain-containing protein.	Uncharacterized protein.	0.510
ASZ78_000147	ASZ78_005552	A0A226NAA5	A0A226NKC3	Thioredoxin domain-containing protein.	RING-type domain-containing protein.	0.509
ASZ78_000147	ASZ78_011692	A0A226NAA5	A0A226M8B0	Thioredoxin domain-containing protein.	Uncharacterized protein.	0.509
ASZ78_000147	ASZ78_016342	A0A226NAA5	A0A226MKV2	Thioredoxin domain-containing protein.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.525
ASZ78_000147	ASZ78_016443	A0A226NAA5	A0A226MS90	Thioredoxin domain-containing protein.	Uncharacterized protein.	0.509
ASZ78_000276	ASZ78_000277	A0A226N1Q9	A0A226N2E4	Uncharacterized protein.	Uncharacterized protein.	0.947
ASZ78_000276	ASZ78_001562	A0A226N1Q9	A0A226NCC4	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.414
ASZ78_000276	ASZ78_003778	A0A226N1Q9	A0A226MNQ7	Uncharacterized protein.	CARD domain-containing protein.	0.400
ASZ78_000276	ASZ78_011896	A0A226N1Q9	A0A226NFU7	Uncharacterized protein.	Tyrosine-protein kinase.	0.419
ASZ78_000277	ASZ78_000276	A0A226N2E4	A0A226N1Q9	Uncharacterized protein.	Uncharacterized protein.	0.947
ASZ78_000277	ASZ78_001562	A0A226N2E4	A0A226NCC4	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.414
ASZ78_000277	ASZ78_003778	A0A226N2E4	A0A226MNQ7	Uncharacterized protein.	CARD domain-containing protein.	0.400
ASZ78_000277	ASZ78_011896	A0A226N2E4	A0A226NFU7	Uncharacterized protein.	Tyrosine-protein kinase.	0.419
ASZ78_000547	ASZ78_000796	A0A226MP91	A0A226MYV0	Uncharacterized protein.	Uncharacterized protein.	0.557
ASZ78_000547	ASZ78_001638	A0A226MP91	A0A226MIV8	Uncharacterized protein.	Uncharacterized protein.	0.854
ASZ78_000547	ASZ78_002069	A0A226MP91	A0A226NA45	Uncharacterized protein.	Uncharacterized protein.	0.512
ASZ78_000547	ASZ78_005300	A0A226MP91	A0A226NC50	Uncharacterized protein.	Uncharacterized protein.	0.455
ASZ78_000547	ASZ78_005425	A0A226MP91	A0A226MIS4	Uncharacterized protein.	Uncharacterized protein.	0.449