(60 nodes) Positive regulation of apoptotic signaling pathway network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_010351	Uncharacterized protein. (273 aa)
	ASZ78_005471	Uncharacterized protein. (517 aa)
	ASZ78_010056	Uncharacterized protein. (472 aa)
	ASZ78_012257	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
	ASZ78_016680	Uncharacterized protein. (924 aa)
	ASZ78_010048	Uncharacterized protein. (687 aa)
	ASZ78_002167	UDENN FLCN/SMCR8-type domain-containing protein. (564 aa)
	ASZ78_010292	Uncharacterized protein. (433 aa)
	ASZ78_002232	Uncharacterized protein. (740 aa)
	ASZ78_001516	Uncharacterized protein; Belongs to the peptidase C19 family. (732 aa)
	ASZ78_006135	Uncharacterized protein. (622 aa)
	ASZ78_005901	Uncharacterized protein. (212 aa)
	ASZ78_008011	Protein disulfide-isomerase. (499 aa)
	ASZ78_008036	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (283 aa)
	ASZ78_006399	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (796 aa)
	ASZ78_008675	Uncharacterized protein. (195 aa)
	ASZ78_013736	CARD domain-containing protein. (223 aa)
	ASZ78_012083	Uncharacterized protein. (145 aa)
	ASZ78_011170	RING-type domain-containing protein. (109 aa)
	ASZ78_014953	Uncharacterized protein; Belongs to the peptidase C14A family. (371 aa)
	ASZ78_001892	Deacetylase sirtuin-type domain-containing protein. (593 aa)
	ASZ78_012112	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (410 aa)
	ASZ78_012443	Uncharacterized protein. (876 aa)
	ASZ78_015109	Death domain-containing protein. (297 aa)
	ASZ78_002137	PDZ domain-containing protein. (309 aa)
	ASZ78_002817	Homeobox domain-containing protein. (195 aa)
	ASZ78_013850	Uncharacterized protein. (744 aa)
	ASZ78_004040	Uncharacterized protein. (123 aa)
	ASZ78_005418	Ribosomal_S3_C domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (180 aa)
	ASZ78_009841	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	ASZ78_016579	Uncharacterized protein. (554 aa)
	ASZ78_003835	Uncharacterized protein. (495 aa)
	ASZ78_009516	c-SKI_SMAD_bind domain-containing protein. (690 aa)
	ASZ78_003778	CARD domain-containing protein. (117 aa)
	ASZ78_017030	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (229 aa)
	ASZ78_008464	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (426 aa)
	ASZ78_012879	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (754 aa)
	ASZ78_003638	BRICHOS domain-containing protein. (262 aa)
	ASZ78_000093	BZIP domain-containing protein. (250 aa)
	ASZ78_011456	UBX domain-containing protein. (727 aa)
	ASZ78_006361	NTR domain-containing protein. (224 aa)
	ASZ78_010759	Uncharacterized protein. (615 aa)
	ASZ78_002408	Uncharacterized protein. (311 aa)
	ASZ78_013172	TGF_BETA_2 domain-containing protein. (424 aa)
	ASZ78_006529	Uncharacterized protein. (166 aa)
	ASZ78_008184	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (253 aa)
	ASZ78_016260	Tyrosine-protein phosphatase domain-containing protein. (306 aa)
	ASZ78_005300	Uncharacterized protein. (997 aa)
	ASZ78_001562	Non-specific serine/threonine protein kinase. (525 aa)
	ASZ78_017101	SERPIN domain-containing protein; Belongs to the serpin family. (370 aa)
	ASZ78_016632	Uncharacterized protein. (325 aa)
	ASZ78_015054	TGF_BETA_2 domain-containing protein. (392 aa)
	ASZ78_014613	Uncharacterized protein. (882 aa)
	ASZ78_014622	Uncharacterized protein. (505 aa)
	ASZ78_015446	Uncharacterized protein. (1071 aa)
	ASZ78_011896	Tyrosine-protein kinase. (305 aa)
	ASZ78_008214	Cytoplasmic protein. (380 aa)
	ASZ78_003001	Tyrosine-protein phosphatase domain-containing protein. (318 aa)
	ASZ78_013539	Homeobox domain-containing protein. (149 aa)
	ASZ78_004707	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000093	ASZ78_001892	A0A226MU22	A0A226MDM0	BZIP domain-containing protein.	Deacetylase sirtuin-type domain-containing protein.	0.536
ASZ78_000093	ASZ78_002232	A0A226MU22	A0A226NN90	BZIP domain-containing protein.	Uncharacterized protein.	0.450
ASZ78_001516	ASZ78_002232	A0A226N0F9	A0A226NN90	Uncharacterized protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.665
ASZ78_001516	ASZ78_006135	A0A226N0F9	A0A226MZ62	Uncharacterized protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.980
ASZ78_001516	ASZ78_006529	A0A226N0F9	A0A226N7F1	Uncharacterized protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.732
ASZ78_001516	ASZ78_011170	A0A226N0F9	A0A226MAY7	Uncharacterized protein; Belongs to the peptidase C19 family.	RING-type domain-containing protein.	0.677
ASZ78_001516	ASZ78_012443	A0A226N0F9	A0A226MEI6	Uncharacterized protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.919
ASZ78_001516	ASZ78_014953	A0A226N0F9	A0A226MCV6	Uncharacterized protein; Belongs to the peptidase C19 family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.519
ASZ78_001562	ASZ78_006135	A0A226NCC4	A0A226MZ62	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.400
ASZ78_001562	ASZ78_008214	A0A226NCC4	A0A226NGC7	Non-specific serine/threonine protein kinase.	Cytoplasmic protein.	0.979
ASZ78_001562	ASZ78_011896	A0A226NCC4	A0A226NFU7	Non-specific serine/threonine protein kinase.	Tyrosine-protein kinase.	0.532
ASZ78_001562	ASZ78_012112	A0A226NCC4	A0A226ME75	Non-specific serine/threonine protein kinase.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.460
ASZ78_001562	ASZ78_014953	A0A226NCC4	A0A226MCV6	Non-specific serine/threonine protein kinase.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.518
ASZ78_001892	ASZ78_000093	A0A226MDM0	A0A226MU22	Deacetylase sirtuin-type domain-containing protein.	BZIP domain-containing protein.	0.536
ASZ78_001892	ASZ78_006399	A0A226MDM0	A0A226N634	Deacetylase sirtuin-type domain-containing protein.	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.	0.858
ASZ78_001892	ASZ78_016632	A0A226MDM0	A0A226NDG0	Deacetylase sirtuin-type domain-containing protein.	Uncharacterized protein.	0.546
ASZ78_002137	ASZ78_002232	A0A226MFY7	A0A226NN90	PDZ domain-containing protein.	Uncharacterized protein.	0.498
ASZ78_002137	ASZ78_005300	A0A226MFY7	A0A226NC50	PDZ domain-containing protein.	Uncharacterized protein.	0.560
ASZ78_002232	ASZ78_000093	A0A226NN90	A0A226MU22	Uncharacterized protein.	BZIP domain-containing protein.	0.450
ASZ78_002232	ASZ78_001516	A0A226NN90	A0A226N0F9	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.665