(35 nodes) Positive regulation of cation channel activity network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_005859	SH3 domain-containing protein. (463 aa)
	ASZ78_016958	Ig-like domain-containing protein. (492 aa)
	ASZ78_009679	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (224 aa)
	ASZ78_007850	ANK_REP_REGION domain-containing protein. (74 aa)
	ASZ78_007849	Uncharacterized protein. (168 aa)
	ASZ78_011846	Uncharacterized protein. (1066 aa)
	ASZ78_011225	SOAR domain-containing protein. (457 aa)
	ASZ78_011226	Uncharacterized protein. (59 aa)
	ASZ78_016641	SAM domain-containing protein. (196 aa)
	ASZ78_012082	Uncharacterized protein. (903 aa)
	ASZ78_001538	Uncharacterized protein. (1402 aa)
	ASZ78_004945	Uncharacterized protein. (235 aa)
	ASZ78_006570	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
	ASZ78_009971	Protein kinase domain-containing protein. (513 aa)
	ASZ78_003694	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
	ASZ78_001036	SAM domain-containing protein. (703 aa)
	ASZ78_016921	Ig-like domain-containing protein. (521 aa)
	ASZ78_010774	Uncharacterized protein. (141 aa)
	ASZ78_007199	Uncharacterized protein. (292 aa)
	ASZ78_001526	Arc_C domain-containing protein. (404 aa)
	ASZ78_012312	Uncharacterized protein. (205 aa)
	ASZ78_005012	Uncharacterized protein. (378 aa)
	ASZ78_012644	Uncharacterized protein. (290 aa)
	ASZ78_005013	Uncharacterized protein. (188 aa)
	ASZ78_002445	ABC transmembrane type-1 domain-containing protein. (480 aa)
	ASZ78_001368	Uncharacterized protein. (402 aa)
	ASZ78_006643	Uncharacterized protein. (981 aa)
	ASZ78_001539	Uncharacterized protein. (1005 aa)
	ASZ78_007501	AKAP7_NLS domain-containing protein. (291 aa)
	ASZ78_011626	Uncharacterized protein. (267 aa)
	ASZ78_002792	Uncharacterized protein. (1004 aa)
	ASZ78_016662	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	ASZ78_010019	AKAP7_NLS domain-containing protein. (190 aa)
	ASZ78_010018	AKAP7_RIRII_bdg domain-containing protein. (83 aa)
	ASZ78_014295	Uncharacterized protein. (234 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_001036	ASZ78_011225	A0A226N6J9	A0A226MDM2	SAM domain-containing protein.	SOAR domain-containing protein.	0.897
ASZ78_001036	ASZ78_011226	A0A226N6J9	A0A226MDL7	SAM domain-containing protein.	Uncharacterized protein.	0.970
ASZ78_001036	ASZ78_016641	A0A226N6J9	A0A226MDG1	SAM domain-containing protein.	SAM domain-containing protein.	0.970
ASZ78_001538	ASZ78_001539	A0A226NES2	A0A226NET6	Uncharacterized protein.	Uncharacterized protein.	0.936
ASZ78_001539	ASZ78_001538	A0A226NET6	A0A226NES2	Uncharacterized protein.	Uncharacterized protein.	0.936
ASZ78_005012	ASZ78_005013	A0A226MWL1	A0A226MWH3	Uncharacterized protein.	Uncharacterized protein.	0.944
ASZ78_005013	ASZ78_005012	A0A226MWH3	A0A226MWL1	Uncharacterized protein.	Uncharacterized protein.	0.944
ASZ78_005859	ASZ78_006570	A0A226NMN3	A0A226NBG1	SH3 domain-containing protein.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.937
ASZ78_005859	ASZ78_009679	A0A226NMN3	A0A226ML27	SH3 domain-containing protein.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.963
ASZ78_006570	ASZ78_005859	A0A226NBG1	A0A226NMN3	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	SH3 domain-containing protein.	0.937
ASZ78_006570	ASZ78_009679	A0A226NBG1	A0A226ML27	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.935
ASZ78_007199	ASZ78_011626	A0A226N0U8	A0A226NG44	Uncharacterized protein.	Uncharacterized protein.	0.418
ASZ78_007849	ASZ78_007850	A0A226MJ52	A0A226MJ80	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.965
ASZ78_007849	ASZ78_012082	A0A226MJ52	A0A226MD03	Uncharacterized protein.	Uncharacterized protein.	0.770
ASZ78_007850	ASZ78_007849	A0A226MJ80	A0A226MJ52	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.965
ASZ78_007850	ASZ78_012082	A0A226MJ80	A0A226MD03	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.960
ASZ78_009679	ASZ78_005859	A0A226ML27	A0A226NMN3	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	SH3 domain-containing protein.	0.963
ASZ78_009679	ASZ78_006570	A0A226ML27	A0A226NBG1	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.	0.935
ASZ78_011225	ASZ78_001036	A0A226MDM2	A0A226N6J9	SOAR domain-containing protein.	SAM domain-containing protein.	0.897
ASZ78_011225	ASZ78_016641	A0A226MDM2	A0A226MDG1	SOAR domain-containing protein.	SAM domain-containing protein.	0.900