(24 nodes) Toll/interleukin-1 receptor homology (TIR) domain superfamily network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_016601	TIR domain-containing protein. (366 aa)
	ASZ78_002560	TIR domain-containing protein. (938 aa)
	ASZ78_013317	TIR domain-containing protein; Belongs to the Toll-like receptor family. (776 aa)
	ASZ78_003088	TIR domain-containing protein. (726 aa)
	ASZ78_010634	SEFIR domain-containing protein. (603 aa)
	ASZ78_015469	TIR domain-containing protein. (310 aa)
	ASZ78_013118	TIR domain-containing protein; Belongs to the Toll-like receptor family. (896 aa)
	ASZ78_012508	SAM domain-containing protein. (715 aa)
	ASZ78_010603	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (736 aa)
	ASZ78_011482	Uncharacterized protein. (493 aa)
	ASZ78_011187	DBB domain-containing protein. (193 aa)
	ASZ78_001876	DBB domain-containing protein. (795 aa)
	ASZ78_007328	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1357 aa)
	ASZ78_005609	TIR domain-containing protein; Belongs to the Toll-like receptor family. (818 aa)
	ASZ78_005610	TIR domain-containing protein. (397 aa)
	ASZ78_010074	Uncharacterized protein. (407 aa)
	ASZ78_015256	TIR domain-containing protein; Belongs to the Toll-like receptor family. (890 aa)
	ASZ78_006395	TIR domain-containing protein. (213 aa)
	ASZ78_006394	Uncharacterized protein. (560 aa)
	ASZ78_016219	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (299 aa)
	ASZ78_001051	Uncharacterized protein. (436 aa)
	ASZ78_008203	Uncharacterized protein. (535 aa)
	ASZ78_008201	Uncharacterized protein. (563 aa)
	ASZ78_009641	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family. (1107 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_002560	ASZ78_003088	A0A226MD80	A0A226MI42	TIR domain-containing protein.	TIR domain-containing protein.	0.591
ASZ78_002560	ASZ78_005609	A0A226MD80	A0A226NKC0	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.538
ASZ78_002560	ASZ78_005610	A0A226MD80	A0A226NKH4	TIR domain-containing protein.	TIR domain-containing protein.	0.535
ASZ78_002560	ASZ78_009641	A0A226MD80	A0A226NN17	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family.	0.658
ASZ78_002560	ASZ78_010603	A0A226MD80	A0A226MTT9	TIR domain-containing protein.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.774
ASZ78_002560	ASZ78_012508	A0A226MD80	A0A226MRZ7	TIR domain-containing protein.	SAM domain-containing protein.	0.439
ASZ78_002560	ASZ78_013317	A0A226MD80	A0A226MEV2	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.535
ASZ78_002560	ASZ78_015256	A0A226MD80	A0A226NKT0	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.709
ASZ78_002560	ASZ78_015469	A0A226MD80	A0A226ML31	TIR domain-containing protein.	TIR domain-containing protein.	0.765
ASZ78_002560	ASZ78_016219	A0A226MD80	A0A226N889	TIR domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.954
ASZ78_002560	ASZ78_016601	A0A226MD80	A0A226MCY5	TIR domain-containing protein.	TIR domain-containing protein.	0.619
ASZ78_003088	ASZ78_002560	A0A226MI42	A0A226MD80	TIR domain-containing protein.	TIR domain-containing protein.	0.591
ASZ78_003088	ASZ78_005609	A0A226MI42	A0A226NKC0	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.595
ASZ78_003088	ASZ78_005610	A0A226MI42	A0A226NKH4	TIR domain-containing protein.	TIR domain-containing protein.	0.565
ASZ78_003088	ASZ78_007328	A0A226MI42	A0A226NHJ5	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.628
ASZ78_003088	ASZ78_009641	A0A226MI42	A0A226NN17	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family.	0.748
ASZ78_003088	ASZ78_010603	A0A226MI42	A0A226MTT9	TIR domain-containing protein.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.684
ASZ78_003088	ASZ78_013118	A0A226MI42	A0A226MN15	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.604
ASZ78_003088	ASZ78_013317	A0A226MI42	A0A226MEV2	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.590
ASZ78_003088	ASZ78_015256	A0A226MI42	A0A226NKT0	TIR domain-containing protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.735