(16 nodes) Caspase activation via Death Receptors in the presence of ligand network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_011802	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (268 aa)
	ASZ78_011648	TNF receptor-associated factor. (406 aa)
	ASZ78_008184	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (253 aa)
	ASZ78_008840	Uncharacterized protein. (72 aa)
	ASZ78_006529	Uncharacterized protein. (166 aa)
	ASZ78_006135	Uncharacterized protein. (622 aa)
	ASZ78_001146	Uncharacterized protein; Belongs to the peptidase C14A family. (403 aa)
	ASZ78_007906	Uncharacterized protein. (233 aa)
	ASZ78_007905	Uncharacterized protein. (145 aa)
	ASZ78_010603	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (736 aa)
	ASZ78_012926	Uncharacterized protein. (80 aa)
	ASZ78_009492	Death domain-containing protein. (311 aa)
	ASZ78_008885	Uncharacterized protein; Belongs to the peptidase C14A family. (282 aa)
	ASZ78_002816	Uncharacterized protein. (353 aa)
	ASZ78_015109	Death domain-containing protein. (297 aa)
	ASZ78_009641	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family. (1107 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_001146	ASZ78_002816	A0A226MZ58	A0A226MG77	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.893
ASZ78_001146	ASZ78_006135	A0A226MZ58	A0A226MZ62	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.992
ASZ78_001146	ASZ78_006529	A0A226MZ58	A0A226N7F1	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.997
ASZ78_001146	ASZ78_008184	A0A226MZ58	A0A226NAQ4	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.859
ASZ78_001146	ASZ78_008840	A0A226MZ58	A0A226N7L5	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.670
ASZ78_001146	ASZ78_008885	A0A226MZ58	A0A226MQ95	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.973
ASZ78_001146	ASZ78_009492	A0A226MZ58	A0A226MRC9	Uncharacterized protein; Belongs to the peptidase C14A family.	Death domain-containing protein.	0.995
ASZ78_001146	ASZ78_009641	A0A226MZ58	A0A226NN17	Uncharacterized protein; Belongs to the peptidase C14A family.	TIR domain-containing protein; Belongs to the glycosyltransferase 29 family.	0.732
ASZ78_001146	ASZ78_010603	A0A226MZ58	A0A226MTT9	Uncharacterized protein; Belongs to the peptidase C14A family.	TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.	0.479
ASZ78_001146	ASZ78_011648	A0A226MZ58	A0A226NFY8	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF receptor-associated factor.	0.906
ASZ78_001146	ASZ78_011802	A0A226MZ58	A0A226MRU7	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.889
ASZ78_001146	ASZ78_012926	A0A226MZ58	A0A226NN12	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.483
ASZ78_001146	ASZ78_015109	A0A226MZ58	A0A226MFF0	Uncharacterized protein; Belongs to the peptidase C14A family.	Death domain-containing protein.	0.936
ASZ78_002816	ASZ78_001146	A0A226MG77	A0A226MZ58	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.893
ASZ78_002816	ASZ78_006135	A0A226MG77	A0A226MZ62	Uncharacterized protein.	Uncharacterized protein.	0.969
ASZ78_002816	ASZ78_006529	A0A226MG77	A0A226N7F1	Uncharacterized protein.	Uncharacterized protein.	0.986
ASZ78_002816	ASZ78_008184	A0A226MG77	A0A226NAQ4	Uncharacterized protein.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.994
ASZ78_002816	ASZ78_008840	A0A226MG77	A0A226N7L5	Uncharacterized protein.	Uncharacterized protein.	0.841
ASZ78_002816	ASZ78_008885	A0A226MG77	A0A226MQ95	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.635
ASZ78_002816	ASZ78_009492	A0A226MG77	A0A226MRC9	Uncharacterized protein.	Death domain-containing protein.	0.957