(100 nodes) Signaling by NTRKs network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_014723	Protein kinase domain-containing protein. (150 aa)
	ASZ78_004352	G_PROTEIN_RECEP_F1_2 domain-containing protein. (156 aa)
	ASZ78_010209	Protein kinase domain-containing protein. (148 aa)
	ASZ78_013219	Clat_adaptor_s domain-containing protein. (49 aa)
	ASZ78_003556	Helicase ATP-binding domain-containing protein. (131 aa)
	ASZ78_015978	Uncharacterized protein. (98 aa)
	ASZ78_014219	Protein kinase domain-containing protein. (372 aa)
	ASZ78_010782	Uncharacterized protein. (389 aa)
	ASZ78_001857	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (369 aa)
	ASZ78_006854	Uncharacterized protein. (310 aa)
	ASZ78_013227	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (235 aa)
	ASZ78_001652	Uncharacterized protein. (166 aa)
	ASZ78_014936	Uncharacterized protein. (194 aa)
	ASZ78_013345	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (510 aa)
	ASZ78_012041	Mitogen-activated protein kinase. (359 aa)
	ASZ78_015382	Uncharacterized protein. (618 aa)
	ASZ78_006759	P/Homo B domain-containing protein. (648 aa)
	ASZ78_003266	PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (127 aa)
	ASZ78_006127	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa)
	ASZ78_016322	MADS-box domain-containing protein. (437 aa)
	ASZ78_009178	Uncharacterized protein. (525 aa)
	ASZ78_009273	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
	ASZ78_009139	Uncharacterized protein. (151 aa)
	ASZ78_015631	Ribosomal protein S6 kinase. (738 aa)
	ASZ78_011420	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
	ASZ78_010326	Uncharacterized protein; Belongs to the DOCK family. (1754 aa)
	ASZ78_006428	Uncharacterized protein. (224 aa)
	ASZ78_010324	Protein kinase domain-containing protein. (335 aa)
	ASZ78_001784	Uncharacterized protein. (731 aa)
	ASZ78_001776	BZIP domain-containing protein. (329 aa)
	ASZ78_003147	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (914 aa)
	ASZ78_008803	Uncharacterized protein. (284 aa)
	ASZ78_010642	Uncharacterized protein. (189 aa)
	ASZ78_000503	Uncharacterized protein. (116 aa)
	ASZ78_000502	Peptidase_S8 domain-containing protein. (74 aa)
	ASZ78_000501	GF_recep_IV domain-containing protein. (147 aa)
	ASZ78_011824	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (349 aa)
	ASZ78_010169	Uncharacterized protein. (982 aa)
	ASZ78_008290	Uncharacterized protein. (1064 aa)
	ASZ78_007045	AP complex subunit beta. (937 aa)
	ASZ78_013040	Uncharacterized protein. (348 aa)
	ASZ78_012534	Uncharacterized protein. (305 aa)
	ASZ78_012582	Uncharacterized protein. (188 aa)
	ASZ78_003642	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1026 aa)
	ASZ78_004768	Tyrosine-protein kinase receptor. (313 aa)
	ASZ78_004769	Ig-like domain-containing protein. (525 aa)
	ASZ78_011858	WRNPLPNID domain-containing protein. (881 aa)
	ASZ78_007793	Protein kinase domain-containing protein. (332 aa)
	ASZ78_005004	Uncharacterized protein. (1966 aa)
	ASZ78_013233	Uncharacterized protein. (201 aa)
	ASZ78_011086	BHLH domain-containing protein. (125 aa)
	ASZ78_000784	Uncharacterized protein. (1916 aa)
	ASZ78_014399	Dynein light chain. (106 aa)
	ASZ78_001526	Arc_C domain-containing protein. (404 aa)
	ASZ78_000197	Uncharacterized protein. (279 aa)
	ASZ78_006309	Uncharacterized protein. (626 aa)
	ASZ78_005799	Mitogen-activated protein kinase. (351 aa)
	ASZ78_013415	Uncharacterized protein. (1029 aa)
	ASZ78_015368	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
	ASZ78_010523	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (433 aa)
	ASZ78_013259	Protein kinase domain-containing protein. (442 aa)
	ASZ78_013178	ANK_REP_REGION domain-containing protein. (1016 aa)
	ASZ78_013177	BHLH domain-containing protein. (169 aa)
	ASZ78_008014	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (795 aa)
	ASZ78_008138	Tyrosine-protein kinase receptor. (626 aa)
	ASZ78_006501	Uncharacterized protein. (1269 aa)
	ASZ78_009375	Uncharacterized protein. (287 aa)
	ASZ78_003097	Uncharacterized protein. (473 aa)
	ASZ78_016799	Protein kinase domain-containing protein. (343 aa)
	ASZ78_015659	Uncharacterized protein. (759 aa)
	ASZ78_000303	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
	ASZ78_008830	BHLH domain-containing protein. (163 aa)
	ASZ78_013270	Uncharacterized protein. (308 aa)
	ASZ78_006058	Non-specific serine/threonine protein kinase. (585 aa)
	ASZ78_005944	Uncharacterized protein. (346 aa)
	ASZ78_008174	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (996 aa)
	ASZ78_008749	Uncharacterized protein. (303 aa)
	ASZ78_008185	Uncharacterized protein. (795 aa)
	ASZ78_010398	Protein kinase domain-containing protein. (109 aa)
	ASZ78_013828	Uncharacterized protein. (464 aa)
	ASZ78_009780	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1669 aa)
	ASZ78_015056	Uncharacterized protein. (206 aa)
	ASZ78_007514	WRNPLPNID domain-containing protein. (768 aa)
	ASZ78_012998	Uncharacterized protein. (232 aa)
	ASZ78_006016	LisH domain-containing protein. (872 aa)
	ASZ78_015800	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (398 aa)
	ASZ78_014701	Uncharacterized protein. (198 aa)
	ASZ78_014700	Uncharacterized protein. (519 aa)
	ASZ78_016387	BHLH domain-containing protein. (124 aa)
	ASZ78_015285	Uncharacterized protein. (1320 aa)
	ASZ78_000393	CSD_1 domain-containing protein. (290 aa)
	ASZ78_000392	Uncharacterized protein. (457 aa)
	ASZ78_010038	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (412 aa)
	ASZ78_000394	Uncharacterized protein. (189 aa)
	ASZ78_015686	IRS-type PTB domain-containing protein. (513 aa)
	ASZ78_003457	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (402 aa)
	ASZ78_003431	Uncharacterized protein; Belongs to the peptidase S8 family. (943 aa)
	ASZ78_009566	Ras-GEF domain-containing protein. (1063 aa)
	ASZ78_015721	BHLH domain-containing protein. (220 aa)
	ASZ78_009545	Uncharacterized protein. (794 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000197	ASZ78_001776	A0A226N1L0	A0A226MMA0	Uncharacterized protein.	BZIP domain-containing protein.	0.408
ASZ78_000197	ASZ78_005799	A0A226N1L0	A0A226N2T1	Uncharacterized protein.	Mitogen-activated protein kinase.	0.545
ASZ78_000197	ASZ78_005944	A0A226N1L0	A0A226N9X6	Uncharacterized protein.	Uncharacterized protein.	0.904
ASZ78_000197	ASZ78_006058	A0A226N1L0	A0A226N8E6	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.646
ASZ78_000197	ASZ78_008830	A0A226N1L0	A0A226N7K7	Uncharacterized protein.	BHLH domain-containing protein.	0.449
ASZ78_000197	ASZ78_010038	A0A226N1L0	A0A226NM40	Uncharacterized protein.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.616
ASZ78_000197	ASZ78_010209	A0A226N1L0	A0A226M6M3	Uncharacterized protein.	Protein kinase domain-containing protein.	0.607
ASZ78_000197	ASZ78_010324	A0A226N1L0	A0A226MLR9	Uncharacterized protein.	Protein kinase domain-containing protein.	0.594
ASZ78_000197	ASZ78_012041	A0A226N1L0	A0A226MFG6	Uncharacterized protein.	Mitogen-activated protein kinase.	0.545
ASZ78_000197	ASZ78_014219	A0A226N1L0	A0A226M9B4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.628
ASZ78_000197	ASZ78_014723	A0A226N1L0	A0A226NKY2	Uncharacterized protein.	Protein kinase domain-containing protein.	0.768
ASZ78_000197	ASZ78_015368	A0A226N1L0	A0A226N3K9	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.628
ASZ78_000197	ASZ78_015631	A0A226N1L0	A0A226MKA4	Uncharacterized protein.	Ribosomal protein S6 kinase.	0.646
ASZ78_000197	ASZ78_015721	A0A226N1L0	A0A226NPA1	Uncharacterized protein.	BHLH domain-containing protein.	0.449
ASZ78_000197	ASZ78_015800	A0A226N1L0	A0A226NIU3	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.607
ASZ78_000197	ASZ78_016322	A0A226N1L0	A0A226MIP5	Uncharacterized protein.	MADS-box domain-containing protein.	0.497
ASZ78_000303	ASZ78_003147	A0A226N7D2	A0A226MMT1	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.903
ASZ78_000303	ASZ78_004768	A0A226N7D2	A0A226MU43	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Tyrosine-protein kinase receptor.	0.483
ASZ78_000303	ASZ78_004769	A0A226N7D2	A0A226MU66	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Ig-like domain-containing protein.	0.483
ASZ78_000303	ASZ78_005799	A0A226N7D2	A0A226N2T1	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Mitogen-activated protein kinase.	0.511