(13 nodes) Toll-like receptors (TLR) cascades network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_006162	IKBKB_SDD domain-containing protein. (141 aa)
	ASZ78_012926	Uncharacterized protein. (80 aa)
	ASZ78_016007	BZIP domain-containing protein; Belongs to the bZIP family. (314 aa)
	ASZ78_016219	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (299 aa)
	ASZ78_014823	IPT/TIG domain-containing protein. (430 aa)
	ASZ78_006317	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (398 aa)
	ASZ78_011189	Uncharacterized protein. (980 aa)
	ASZ78_002480	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (375 aa)
	ASZ78_000054	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (502 aa)
	ASZ78_002435	BZIP domain-containing protein. (262 aa)
	ASZ78_016594	Protein kinase domain-containing protein. (385 aa)
	ASZ78_012743	ANK_REP_REGION domain-containing protein. (318 aa)
	ASZ78_007167	Protein kinase domain-containing protein. (401 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000054	ASZ78_006162	A0A226MR55	A0A226M971	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	IKBKB_SDD domain-containing protein.	0.971
ASZ78_000054	ASZ78_007167	A0A226MR55	A0A226MCA0	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Protein kinase domain-containing protein.	0.971
ASZ78_000054	ASZ78_011189	A0A226MR55	A0A226MWL5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Uncharacterized protein.	0.641
ASZ78_000054	ASZ78_012743	A0A226MR55	A0A226ME04	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	ANK_REP_REGION domain-containing protein.	0.928
ASZ78_000054	ASZ78_012926	A0A226MR55	A0A226NN12	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Uncharacterized protein.	0.743
ASZ78_000054	ASZ78_014823	A0A226MR55	A0A226N642	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	IPT/TIG domain-containing protein.	0.659
ASZ78_000054	ASZ78_016219	A0A226MR55	A0A226N889	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.997
ASZ78_000054	ASZ78_016594	A0A226MR55	A0A226MHV8	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Protein kinase domain-containing protein.	0.852
ASZ78_002435	ASZ78_002480	A0A226MJ70	A0A226MUJ2	BZIP domain-containing protein.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.487
ASZ78_002435	ASZ78_012743	A0A226MJ70	A0A226ME04	BZIP domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.466
ASZ78_002435	ASZ78_014823	A0A226MJ70	A0A226N642	BZIP domain-containing protein.	IPT/TIG domain-containing protein.	0.404
ASZ78_002435	ASZ78_016219	A0A226MJ70	A0A226N889	BZIP domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.543
ASZ78_002435	ASZ78_016594	A0A226MJ70	A0A226MHV8	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.985
ASZ78_002480	ASZ78_002435	A0A226MUJ2	A0A226MJ70	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	BZIP domain-containing protein.	0.487
ASZ78_002480	ASZ78_016007	A0A226MUJ2	A0A226NAD4	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	BZIP domain-containing protein; Belongs to the bZIP family.	0.487
ASZ78_002480	ASZ78_016594	A0A226MUJ2	A0A226MHV8	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Protein kinase domain-containing protein.	0.964
ASZ78_006162	ASZ78_000054	A0A226M971	A0A226MR55	IKBKB_SDD domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.971
ASZ78_006162	ASZ78_006317	A0A226M971	A0A226N322	IKBKB_SDD domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.504
ASZ78_006162	ASZ78_011189	A0A226M971	A0A226MWL5	IKBKB_SDD domain-containing protein.	Uncharacterized protein.	0.963
ASZ78_006162	ASZ78_012743	A0A226M971	A0A226ME04	IKBKB_SDD domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.996