(62 nodes) Steroid hormone biosynthesis network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_005374	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (377 aa)
	ASZ78_007600	Uncharacterized protein; Belongs to the cytochrome P450 family. (67 aa)
	ASZ78_011236	Uncharacterized protein. (114 aa)
	ASZ78_001199	Uncharacterized protein; Belongs to the cytochrome P450 family. (255 aa)
	ASZ78_007666	Sulfotransferase; Belongs to the sulfotransferase 1 family. (111 aa)
	ASZ78_006239	Uncharacterized protein. (395 aa)
	ASZ78_001702	Uncharacterized protein. (194 aa)
	ASZ78_002734	Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa)
	ASZ78_004340	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	ASZ78_012358	Uncharacterized protein; Belongs to the cytochrome P450 family. (395 aa)
	ASZ78_003592	Uncharacterized protein. (114 aa)
	ASZ78_003591	Uncharacterized protein; Belongs to the cytochrome P450 family. (344 aa)
	ASZ78_010199	Uncharacterized protein. (143 aa)
	ASZ78_013046	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	ASZ78_013047	Uncharacterized protein. (109 aa)
	ASZ78_005919	Uncharacterized protein. (409 aa)
	ASZ78_000099	S5A_REDUCTASE domain-containing protein. (232 aa)
	ASZ78_004042	Uncharacterized protein. (301 aa)
	ASZ78_004043	Uncharacterized protein. (293 aa)
	ASZ78_001708	S5A_REDUCTASE domain-containing protein. (277 aa)
	ASZ78_001707	GDT1 family protein. (215 aa)
	ASZ78_008061	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (262 aa)
	ASZ78_014195	3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (255 aa)
	ASZ78_012565	Uncharacterized protein. (326 aa)
	ASZ78_012563	Uncharacterized protein. (308 aa)
	ASZ78_012564	Uncharacterized protein. (307 aa)
	ASZ78_012566	Uncharacterized protein. (1207 aa)
	ASZ78_015742	Aldo_ket_red domain-containing protein. (313 aa)
	ASZ78_012561	Uncharacterized protein. (638 aa)
	ASZ78_012559	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (531 aa)
	ASZ78_014062	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
	ASZ78_012558	Uncharacterized protein. (543 aa)
	ASZ78_016456	Uncharacterized protein; Belongs to the cytochrome P450 family. (565 aa)
	ASZ78_016461	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	ASZ78_011722	Uncharacterized protein; Belongs to the cytochrome P450 family. (517 aa)
	ASZ78_000590	Uncharacterized protein; Belongs to the cytochrome P450 family. (526 aa)
	ASZ78_000589	Uncharacterized protein; Belongs to the cytochrome P450 family. (505 aa)
	ASZ78_016410	Uncharacterized protein. (389 aa)
	ASZ78_000169	Uncharacterized protein. (332 aa)
	ASZ78_006416	Uncharacterized protein. (153 aa)
	ASZ78_007822	Uncharacterized protein; Belongs to the cytochrome P450 family. (408 aa)
	ASZ78_010464	Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
	ASZ78_001880	Uncharacterized protein; Belongs to the cytochrome P450 family. (329 aa)
	ASZ78_008071	Uncharacterized protein. (271 aa)
	ASZ78_013163	Uncharacterized protein. (1076 aa)
	ASZ78_011978	Uncharacterized protein; Belongs to the cytochrome P450 family. (492 aa)
	ASZ78_011979	Uncharacterized protein; Belongs to the cytochrome P450 family. (456 aa)
	ASZ78_008478	Uncharacterized protein. (189 aa)
	ASZ78_013796	Uncharacterized protein. (312 aa)
	ASZ78_003073	Uncharacterized protein. (118 aa)
	ASZ78_010870	Sulfatase domain-containing protein. (159 aa)
	ASZ78_007594	Uncharacterized protein; Belongs to the cytochrome P450 family. (506 aa)
	ASZ78_010871	Sulfatase domain-containing protein. (342 aa)
	ASZ78_008356	Sulfotransferase; Belongs to the sulfotransferase 1 family. (288 aa)
	ASZ78_009760	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (255 aa)
	ASZ78_005072	Uncharacterized protein; Belongs to the cytochrome P450 family. (542 aa)
	ASZ78_014608	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (547 aa)
	ASZ78_014003	Sulfatase domain-containing protein. (579 aa)
	ASZ78_014004	Uncharacterized protein. (709 aa)
	ASZ78_005704	Uncharacterized protein; Belongs to the cytochrome P450 family. (603 aa)
	ASZ78_004675	Uncharacterized protein; Belongs to the cytochrome P450 family. (563 aa)
	ASZ78_004676	Uncharacterized protein. (501 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000099	ASZ78_000589	A0A226MEK9	A0A226MPE6	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_000590	A0A226MEK9	A0A226MP39	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_001199	A0A226MEK9	A0A226M8Q0	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_001702	A0A226MEK9	A0A226MA85	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.429
ASZ78_000099	ASZ78_001708	A0A226MEK9	A0A226MHA7	S5A_REDUCTASE domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.991
ASZ78_000099	ASZ78_001880	A0A226MEK9	A0A226MX14	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_003073	A0A226MEK9	A0A226N548	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.960
ASZ78_000099	ASZ78_003591	A0A226MEK9	A0A226MAY9	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_003592	A0A226MEK9	A0A226MAX9	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.429
ASZ78_000099	ASZ78_004042	A0A226MEK9	A0A226MH30	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.493
ASZ78_000099	ASZ78_004043	A0A226MEK9	A0A226MH53	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.493
ASZ78_000099	ASZ78_004340	A0A226MEK9	A0A226MAP1	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_005072	A0A226MEK9	A0A226NCX7	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.518
ASZ78_000099	ASZ78_005374	A0A226MEK9	A0A226NNJ1	S5A_REDUCTASE domain-containing protein.	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.	0.959
ASZ78_000099	ASZ78_005919	A0A226MEK9	A0A226MCG1	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.925
ASZ78_000099	ASZ78_006239	A0A226MEK9	A0A226MA67	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.429
ASZ78_000099	ASZ78_006416	A0A226MEK9	A0A226MSB6	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein.	0.952
ASZ78_000099	ASZ78_007594	A0A226MEK9	A0A226N7F6	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.464
ASZ78_000099	ASZ78_007600	A0A226MEK9	A0A226M721	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.429
ASZ78_000099	ASZ78_007822	A0A226MEK9	A0A226MSF7	S5A_REDUCTASE domain-containing protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.942