(38 nodes) Cytosolic DNA-sensing pathway network (Callipepla squamata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ASZ78_015702	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (657 aa)
	ASZ78_010788	Uncharacterized protein. (724 aa)
	ASZ78_014823	IPT/TIG domain-containing protein. (430 aa)
	ASZ78_001799	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1397 aa)
	ASZ78_005053	RPOLD domain-containing protein. (290 aa)
	ASZ78_014114	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (304 aa)
	ASZ78_015803	Protein kinase domain-containing protein. (819 aa)
	ASZ78_006802	Protein kinase domain-containing protein. (626 aa)
	ASZ78_015319	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (314 aa)
	ASZ78_006162	IKBKB_SDD domain-containing protein. (141 aa)
	ASZ78_001734	Uncharacterized protein. (75 aa)
	ASZ78_001733	Uncharacterized protein. (195 aa)
	ASZ78_007167	Protein kinase domain-containing protein. (401 aa)
	ASZ78_007884	ANK_REP_REGION domain-containing protein. (314 aa)
	ASZ78_016494	IRF tryptophan pentad repeat domain-containing protein. (509 aa)
	ASZ78_012743	ANK_REP_REGION domain-containing protein. (318 aa)
	ASZ78_015387	Uncharacterized protein. (1049 aa)
	ASZ78_015515	Uncharacterized protein. (804 aa)
	ASZ78_003169	Uncharacterized protein. (67 aa)
	ASZ78_015703	Uncharacterized protein; Belongs to the RNA polymerase beta chain family. (456 aa)
	ASZ78_013375	Uncharacterized protein; Belongs to the peptidase C14A family. (438 aa)
	ASZ78_003798	Uncharacterized protein. (195 aa)
	ASZ78_007964	C-C motif chemokine. (91 aa)
	ASZ78_007963	C-C motif chemokine. (161 aa)
	ASZ78_008298	Uncharacterized protein. (280 aa)
	ASZ78_000607	Uncharacterized protein. (299 aa)
	ASZ78_011767	Uncharacterized protein. (130 aa)
	ASZ78_016862	RNA_pol_L_2 domain-containing protein. (128 aa)
	ASZ78_007652	Interleukin-18. (196 aa)
	ASZ78_011189	Uncharacterized protein. (980 aa)
	ASZ78_001979	Uncharacterized protein. (138 aa)
	ASZ78_007057	CARD_2 domain-containing protein. (586 aa)
	ASZ78_007911	Uncharacterized protein. (382 aa)
	ASZ78_006135	Uncharacterized protein. (622 aa)
	ASZ78_014421	Uncharacterized protein. (127 aa)
	ASZ78_006282	Uncharacterized protein. (215 aa)
	ASZ78_010532	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	ASZ78_016936	Mab-21 domain-containing protein. (313 aa)

Your Current Organism:

Callipepla squamata

NCBI taxonomy Id: 9009
Other names: C. squamata, scaled quail

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASZ78_000607	ASZ78_001799	A0A226MP67	A0A226NC74	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.998
ASZ78_000607	ASZ78_001979	A0A226MP67	A0A226MXZ5	Uncharacterized protein.	Uncharacterized protein.	0.997
ASZ78_000607	ASZ78_003169	A0A226MP67	A0A226MGG0	Uncharacterized protein.	Uncharacterized protein.	0.997
ASZ78_000607	ASZ78_005053	A0A226MP67	A0A226NCV4	Uncharacterized protein.	RPOLD domain-containing protein.	0.998
ASZ78_000607	ASZ78_006282	A0A226MP67	A0A226N1Z0	Uncharacterized protein.	Uncharacterized protein.	0.998
ASZ78_000607	ASZ78_010532	A0A226MP67	A0A226N3M7	Uncharacterized protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.998
ASZ78_000607	ASZ78_014114	A0A226MP67	A0A226NCZ2	Uncharacterized protein.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.991
ASZ78_000607	ASZ78_014421	A0A226MP67	A0A226N0U7	Uncharacterized protein.	Uncharacterized protein.	0.998
ASZ78_000607	ASZ78_015319	A0A226MP67	A0A226NMF2	Uncharacterized protein.	DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.	0.991
ASZ78_000607	ASZ78_015515	A0A226MP67	A0A226MGD6	Uncharacterized protein.	Uncharacterized protein.	0.998
ASZ78_000607	ASZ78_015702	A0A226MP67	A0A226NPJ4	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988
ASZ78_000607	ASZ78_015703	A0A226MP67	A0A226NNE7	Uncharacterized protein.	Uncharacterized protein; Belongs to the RNA polymerase beta chain family.	0.988
ASZ78_000607	ASZ78_016862	A0A226MP67	A0A226MU74	Uncharacterized protein.	RNA_pol_L_2 domain-containing protein.	0.999
ASZ78_001733	ASZ78_008298	A0A226M9I9	A0A226MNA1	Uncharacterized protein.	Uncharacterized protein.	0.408
ASZ78_001734	ASZ78_008298	A0A226M9I8	A0A226MNA1	Uncharacterized protein.	Uncharacterized protein.	0.408
ASZ78_001799	ASZ78_000607	A0A226NC74	A0A226MP67	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.998
ASZ78_001799	ASZ78_001979	A0A226NC74	A0A226MXZ5	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.997
ASZ78_001799	ASZ78_003169	A0A226NC74	A0A226MGG0	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.998
ASZ78_001799	ASZ78_005053	A0A226NC74	A0A226NCV4	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RPOLD domain-containing protein.	0.999
ASZ78_001799	ASZ78_006282	A0A226NC74	A0A226N1Z0	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.999