(43 nodes) Mismatch repair network (Colinus virginianus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H355_003936	MUTSd domain-containing protein. (286 aa)
	H355_010395	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (868 aa)
	H355_009076	DNA_MISMATCH_REPAIR_2 domain-containing protein. (269 aa)
	H355_009305	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (362 aa)
	H355_003939	Uncharacterized protein. (620 aa)
	H355_000717	AAA domain-containing protein. (362 aa)
	H355_010398	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1237 aa)
	H355_000076	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	H355_008842	TFIIIC_sub6 domain-containing protein. (265 aa)
	H355_005695	Uncharacterized protein. (467 aa)
	H355_017058	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (371 aa)
	H355_003297	Uncharacterized protein. (113 aa)
	H355_002123	Uncharacterized protein. (69 aa)
	H355_016454	Uncharacterized protein. (1425 aa)
	H355_000224	DNA_MISMATCH_REPAIR_2 domain-containing protein. (809 aa)
	H355_002124	COS domain-containing protein. (141 aa)
	H355_008881	Rep_fac_C domain-containing protein. (198 aa)
	H355_016430	Exonuclease domain-containing protein. (294 aa)
	H355_005418	F-box domain-containing protein. (918 aa)
	H355_011115	Uncharacterized protein. (461 aa)
	H355_005723	HMG box domain-containing protein. (576 aa)
	H355_011311	PPIase cyclophilin-type domain-containing protein. (101 aa)
	H355_011520	DNA_LIGASE_A3 domain-containing protein; Belongs to the ATP-dependent DNA ligase family. (785 aa)
	H355_003935	DNA_MISMATCH_REPAIR_2 domain-containing protein. (94 aa)
	H355_003937	MutS_I domain-containing protein. (109 aa)
	H355_000407	Uncharacterized protein. (881 aa)
	H355_002998	Replication factor C subunit 1. (1184 aa)
	H355_001971	Mlh1_C domain-containing protein. (423 aa)
	H355_003646	RPA_C domain-containing protein. (292 aa)
	H355_001236	Uncharacterized protein. (96 aa)
	H355_006729	Exonuclease domain-containing protein. (389 aa)
	H355_014855	AAA domain-containing protein. (1724 aa)
	H355_014174	AAA domain-containing protein. (329 aa)
	H355_002587	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
	H355_011289	AAA domain-containing protein. (374 aa)
	H355_007595	Exonuclease domain-containing protein. (356 aa)
	H355_011262	Uncharacterized protein. (129 aa)
	H355_013722	Uncharacterized protein. (799 aa)
	H355_001647	Uncharacterized protein. (355 aa)
	H355_009074	MUTSd domain-containing protein. (510 aa)
	H355_004413	Uncharacterized protein. (540 aa)
	H355_015086	Uncharacterized protein. (404 aa)
	H355_003938	DNA_MISMATCH_REPAIR_2 domain-containing protein. (98 aa)

Your Current Organism:

Colinus virginianus

NCBI taxonomy Id: 9014
Other names: C. virginianus, bobwhite quail, common bobwhite, northern bobwhite

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H355_000076	H355_000224	A0A226P436	A0A226NYW4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.896
H355_000076	H355_000407	A0A226P436	A0A226PTH6	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.965
H355_000076	H355_000717	A0A226P436	A0A226PSR4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	AAA domain-containing protein.	0.999
H355_000076	H355_001236	A0A226P436	A0A226PZH9	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.740
H355_000076	H355_001647	A0A226P436	A0A226PPL8	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.999
H355_000076	H355_001971	A0A226P436	A0A226PUZ7	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Mlh1_C domain-containing protein.	0.977
H355_000076	H355_002998	A0A226P436	A0A226PUJ9	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Replication factor C subunit 1.	0.998
H355_000076	H355_003297	A0A226P436	A0A226P0F2	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.679
H355_000076	H355_003646	A0A226P436	A0A226P5R6	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	RPA_C domain-containing protein.	0.941
H355_000076	H355_003935	A0A226P436	A0A226PT19	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.909
H355_000076	H355_003936	A0A226P436	A0A226PRM5	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	MUTSd domain-containing protein.	0.909
H355_000076	H355_003937	A0A226P436	A0A226PT37	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	MutS_I domain-containing protein.	0.909
H355_000076	H355_003938	A0A226P436	A0A226PRD0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.909
H355_000076	H355_003939	A0A226P436	A0A226PSJ6	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.948
H355_000076	H355_004413	A0A226P436	A0A226PQ61	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.901
H355_000076	H355_005418	A0A226P436	A0A226NRF4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	F-box domain-containing protein.	0.970
H355_000076	H355_005695	A0A226P436	A0A226P1G6	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.999
H355_000076	H355_005723	A0A226P436	A0A226NQV0	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	HMG box domain-containing protein.	0.890
H355_000076	H355_006729	A0A226P436	A0A226P9D4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Exonuclease domain-containing protein.	0.923
H355_000076	H355_007595	A0A226P436	A0A226PH45	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Exonuclease domain-containing protein.	0.923