Amphiregulin.

Betacellulin.

Amphiregulin.

Uncharacterized protein.

Amphiregulin.

Tyrosine-protein kinase CSK; Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C- terminal tails of Src-family kinases (SFKs). Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma mem [...]

Amphiregulin.

Uncharacterized protein.

Amphiregulin.

Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...]

Amphiregulin.

Epigen; Promotes the growth of epithelial cells.

Amphiregulin.

Receptor protein-tyrosine kinase.

Amphiregulin.

Protein kinase domain-containing protein.

Amphiregulin.

Receptor protein-tyrosine kinase.

Amphiregulin.

EGF-like domain-containing protein.

Amphiregulin.

GRB2 associated binding protein 1.

Amphiregulin.

Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.

Amphiregulin.

Proheparin-binding EGF-like growth factor; May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF (By similarity). Plays an important role in the proper development of cranial nerves by inhibiting the migration of the cranial neural crest cells (NCCs) into the odd-numbered neuromeres (r3 and r5) of the hindbrain Plays a role in mediating v-Jun-induced oncogenic tra [...]

Amphiregulin.

Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.

Amphiregulin.

Tyrosine-protein phosphatase non-receptor type 11; This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates (By similarity). May play a positive role during the stages of erythroid cell proliferation.

Amphiregulin.

Endophilin-A3; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity). Implicated in endocytosis of yolk proteins during oogenesis.

Amphiregulin.

Uncharacterized protein.

Amphiregulin.

Uncharacterized protein.

Amphiregulin.

SOS Ras/Rac guanine nucleotide exchange factor 1.

Amphiregulin.

Protein sprouty homolog 2; May play an important role in FGF-mediated patterning of the mid/hindbrain region by acting to modulate the signaling effects of FGF8 through participation in a regulatory negative feedback loop.