(6 nodes) Cytotoxic T-lymphocyte protein 4/CD28, and CD28 dependent Vav1 pathway network (Gallus gallus)

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Your Input:
	CD40LG	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family. (272 aa)
	CTLA4	Cytotoxic T-lymphocyte-associated protein 4. (205 aa)
	CD28	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation. (304 aa)
	CD80	Uncharacterized protein. (316 aa)
	CD86	Uncharacterized protein. (319 aa)
	CD40	Uncharacterized protein. (299 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD28	CD40	ENSGALP00000014099	ENSGALP00000038316	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	Uncharacterized protein.	0.588
CD28	CD40LG	ENSGALP00000014099	ENSGALP00000010340	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	0.851
CD28	CD80	ENSGALP00000014099	ENSGALP00000024911	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	Uncharacterized protein.	0.993
CD28	CD86	ENSGALP00000014099	ENSGALP00000036384	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	Uncharacterized protein.	0.998
CD28	CTLA4	ENSGALP00000014099	ENSGALP00000014096	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	Cytotoxic T-lymphocyte-associated protein 4.	0.755
CD40	CD28	ENSGALP00000038316	ENSGALP00000014099	Uncharacterized protein.	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	0.588
CD40	CD40LG	ENSGALP00000038316	ENSGALP00000010340	Uncharacterized protein.	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	0.999
CD40	CD80	ENSGALP00000038316	ENSGALP00000024911	Uncharacterized protein.	Uncharacterized protein.	0.986
CD40	CD86	ENSGALP00000038316	ENSGALP00000036384	Uncharacterized protein.	Uncharacterized protein.	0.986
CD40	CTLA4	ENSGALP00000038316	ENSGALP00000014096	Uncharacterized protein.	Cytotoxic T-lymphocyte-associated protein 4.	0.775
CD40LG	CD28	ENSGALP00000010340	ENSGALP00000014099	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	0.851
CD40LG	CD40	ENSGALP00000010340	ENSGALP00000038316	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.999
CD40LG	CD80	ENSGALP00000010340	ENSGALP00000024911	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.948
CD40LG	CD86	ENSGALP00000010340	ENSGALP00000036384	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.948
CD40LG	CTLA4	ENSGALP00000010340	ENSGALP00000014096	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	Cytotoxic T-lymphocyte-associated protein 4.	0.854
CD80	CD28	ENSGALP00000024911	ENSGALP00000014099	Uncharacterized protein.	T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation.	0.993
CD80	CD40	ENSGALP00000024911	ENSGALP00000038316	Uncharacterized protein.	Uncharacterized protein.	0.986
CD80	CD40LG	ENSGALP00000024911	ENSGALP00000010340	Uncharacterized protein.	CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Induces the activation of NF-kappa-B (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4 (By similarity). Involved in immunoglobulin class switching (By similarity). Belongs to the tumor necrosis factor family.	0.948
CD80	CD86	ENSGALP00000024911	ENSGALP00000036384	Uncharacterized protein.	Uncharacterized protein.	0.992
CD80	CTLA4	ENSGALP00000024911	ENSGALP00000014096	Uncharacterized protein.	Cytotoxic T-lymphocyte-associated protein 4.	0.999