(18 nodes) Chemokine receptors bind chemokines network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCL20	C-C motif chemokine. (100 aa)
	IL8L1	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
	CCR9	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	CCL26	Chemokine. (94 aa)
	CCR6	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	LOC417536	Chemokine. (91 aa)
	CX3CL1	SCY domain-containing protein. (496 aa)
	IL8L2	Interleukin-8; May be an autocrine factor that promotes the growth of fibroblasts and is involved in the neoplastic transformation of fibroblasts by v-Src. Chemotactic for peripheral blood mononuclear cells as well as for heterophils. (103 aa)
	CCL19-2	SCY domain-containing protein. (99 aa)
	CCR7	C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	CCL5	C-C motif chemokine. (90 aa)
	CCR5	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (355 aa)
	CXCR1	Putative C-X-C chemokine receptor type 1, CXCR1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	CCL19	C-C motif chemokine. (108 aa)
	ACKR4	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (385 aa)
	CCR2	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	CCLL4	C-C motif chemokine. (95 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR4	CCL19	ENSGALP00000070964	ENSGALP00000068348	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.981
ACKR4	CCL19-2	ENSGALP00000070964	ENSGALP00000043299	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.981
ACKR4	CCL26	ENSGALP00000070964	ENSGALP00000023471	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Chemokine.	0.582
ACKR4	CCL5	ENSGALP00000070964	ENSGALP00000049143	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.543
ACKR4	CCLL4	ENSGALP00000070964	ENSGALP00000073663	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.521
ACKR4	CX3CL1	ENSGALP00000070964	ENSGALP00000041151	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.544
ACKR4	LOC417536	ENSGALP00000070964	ENSGALP00000040880	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	Chemokine.	0.582
CCL19	ACKR4	ENSGALP00000068348	ENSGALP00000070964	C-C motif chemokine.	Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.981
CCL19	CCL19-2	ENSGALP00000068348	ENSGALP00000043299	C-C motif chemokine.	SCY domain-containing protein.	0.841
CCL19	CCL20	ENSGALP00000068348	ENSGALP00000004738	C-C motif chemokine.	C-C motif chemokine.	0.901
CCL19	CCL26	ENSGALP00000068348	ENSGALP00000023471	C-C motif chemokine.	Chemokine.	0.867
CCL19	CCL5	ENSGALP00000068348	ENSGALP00000049143	C-C motif chemokine.	C-C motif chemokine.	0.988
CCL19	CCLL4	ENSGALP00000068348	ENSGALP00000073663	C-C motif chemokine.	C-C motif chemokine.	0.971
CCL19	CCR2	ENSGALP00000068348	ENSGALP00000072065	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.872
CCL19	CCR5	ENSGALP00000068348	ENSGALP00000053031	C-C motif chemokine.	Chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.933
CCL19	CCR6	ENSGALP00000068348	ENSGALP00000031194	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.868
CCL19	CCR7	ENSGALP00000068348	ENSGALP00000048400	C-C motif chemokine.	C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.999
CCL19	CCR9	ENSGALP00000068348	ENSGALP00000019246	C-C motif chemokine.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.897
CCL19	CX3CL1	ENSGALP00000068348	ENSGALP00000041151	C-C motif chemokine.	SCY domain-containing protein.	0.716
CCL19	CX3CR1	ENSGALP00000068348	ENSGALP00000057621	C-C motif chemokine.	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.700