STRINGSTRING
GBP1 GBP1 DHX58 DHX58 LOC422993 LOC422993 ZNFX1 ZNFX1 EIF2AK2 EIF2AK2 USP41 USP41 IFI6 IFI6 MX1 MX1 RSAD2 RSAD2 EPSTI1 EPSTI1 OASL OASL IRF7 IRF7 CMPK2 CMPK2 LOC770612 LOC770612 IFIH1 IFIH1 RNASEL RNASEL MAVS MAVS TRIM25 TRIM25 IFIT5 IFIT5 PARP12 PARP12 ENSGALP00000065135 ENSGALP00000065135 IFI27L2 IFI27L2 ISG20 ISG20 IFNA3 IFNA3 IRF1 IRF1 IRF9 IRF9 PARP9 PARP9 UBE2L6 UBE2L6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GBP1GB1/RHD3-type G domain-containing protein. (1020 aa)
DHX58Uncharacterized protein. (674 aa)
LOC422993Interferon-inducible transmembrane protein 1. (113 aa)
ZNFX1Zinc finger NFX1-type containing 1. (2027 aa)
EIF2AK2Uncharacterized protein. (550 aa)
USP41Ubiquitin carboxyl-terminal hydrolase. (424 aa)
IFI6Putative ISG12(2) protein. (107 aa)
MX1Interferon-induced GTP-binding protein Mx; Does not show activity against influenza virus, VSV, Thogoto virus or Sendai virus. (705 aa)
RSAD2Viperin. (354 aa)
EPSTI1Uncharacterized protein. (138 aa)
OASLUncharacterized protein. (484 aa)
IRF7Interferon regulatory factor 3; Key transcriptional regulator of type I interferon (IFN)- dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN- stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. May activate transcription by complex formation with other transcriptional factors, possibly members of the STAT family. Binds specifically to the IFN-stimulated response element (ISRE) but not to the [...] (491 aa)
CMPK2Cytidine/uridine monophosphate kinase 2. (221 aa)
LOC770612Uncharacterized protein. (137 aa)
IFIH1Uncharacterized protein. (1102 aa)
RNASELUncharacterized protein. (686 aa)
MAVSCARD_2 domain-containing protein. (641 aa)
TRIM25Tripartite motif containing 25. (633 aa)
IFIT5Uncharacterized protein. (479 aa)
PARP12Poly(ADP-ribose) polymerase family member 12. (501 aa)
ENSGALP00000065135Uncharacterized protein. (150 aa)
IFI27L2Uncharacterized protein. (157 aa)
ISG20Interferon stimulated exonuclease gene 20. (258 aa)
IFNA3Interferon. (193 aa)
IRF1Interferon regulatory factor 1; Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor (By similarity); Belongs to the IRF family. (414 aa)
IRF9IRF tryptophan pentad repeat domain-containing protein. (472 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (775 aa)
UBE2L6UBIQUITIN_CONJUGAT_2 domain-containing protein. (153 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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