(13 nodes) Misfolded protein binding, and Sarcoplasmic reticulum lumen network (Gallus gallus)

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Your Input:
	HSPA5	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] (652 aa)
	DNAJB11	J domain-containing protein. (373 aa)
	CRELD2	Uncharacterized protein. (363 aa)
	DNAJC10	DnaJ heat shock protein family (Hsp40) member C10. (797 aa)
	PDIA6	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (447 aa)
	DNAJC3	DnaJ homolog subfamily C member 3; May be involved in the unfolded protein response (UPR) during ER stress. (504 aa)
	ENSGALP00000051793	Uncharacterized protein. (360 aa)
	HSP90B1	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Has ATPase activity (By similarity). (795 aa)
	HYOU1	Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family. (1069 aa)
	SDF2L1	Stromal cell derived factor 2 like 1. (192 aa)
	MANF	Mesencephalic astrocyte derived neurotrophic factor. (203 aa)
	DNAJB9	J domain-containing protein. (216 aa)
	SIL1	SIL1 nucleotide exchange factor. (467 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRELD2	DNAJB11	ENSGALP00000013913	ENSGALP00000010583	Uncharacterized protein.	J domain-containing protein.	0.738
CRELD2	DNAJB9	ENSGALP00000013913	ENSGALP00000071753	Uncharacterized protein.	J domain-containing protein.	0.504
CRELD2	DNAJC3	ENSGALP00000013913	ENSGALP00000027249	Uncharacterized protein.	DnaJ homolog subfamily C member 3; May be involved in the unfolded protein response (UPR) during ER stress.	0.590
CRELD2	ENSGALP00000051793	ENSGALP00000013913	ENSGALP00000051793	Uncharacterized protein.	Uncharacterized protein.	0.457
CRELD2	HSP90B1	ENSGALP00000013913	ENSGALP00000054843	Uncharacterized protein.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Has ATPase activity (By similarity).	0.624
CRELD2	HSPA5	ENSGALP00000013913	ENSGALP00000001474	Uncharacterized protein.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.535
CRELD2	HYOU1	ENSGALP00000013913	ENSGALP00000057710	Uncharacterized protein.	Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family.	0.780
CRELD2	MANF	ENSGALP00000013913	ENSGALP00000067347	Uncharacterized protein.	Mesencephalic astrocyte derived neurotrophic factor.	0.869
CRELD2	PDIA6	ENSGALP00000013913	ENSGALP00000026487	Uncharacterized protein.	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.	0.573
CRELD2	SDF2L1	ENSGALP00000013913	ENSGALP00000062678	Uncharacterized protein.	Stromal cell derived factor 2 like 1.	0.839
DNAJB11	CRELD2	ENSGALP00000010583	ENSGALP00000013913	J domain-containing protein.	Uncharacterized protein.	0.738
DNAJB11	DNAJC10	ENSGALP00000010583	ENSGALP00000014379	J domain-containing protein.	DnaJ heat shock protein family (Hsp40) member C10.	0.923
DNAJB11	DNAJC3	ENSGALP00000010583	ENSGALP00000027249	J domain-containing protein.	DnaJ homolog subfamily C member 3; May be involved in the unfolded protein response (UPR) during ER stress.	0.968
DNAJB11	ENSGALP00000051793	ENSGALP00000010583	ENSGALP00000051793	J domain-containing protein.	Uncharacterized protein.	0.928
DNAJB11	HSP90B1	ENSGALP00000010583	ENSGALP00000054843	J domain-containing protein.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). Has ATPase activity (By similarity).	0.966
DNAJB11	HSPA5	ENSGALP00000010583	ENSGALP00000001474	J domain-containing protein.	Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...]	0.935
DNAJB11	HYOU1	ENSGALP00000010583	ENSGALP00000057710	J domain-containing protein.	Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family.	0.743
DNAJB11	MANF	ENSGALP00000010583	ENSGALP00000067347	J domain-containing protein.	Mesencephalic astrocyte derived neurotrophic factor.	0.892
DNAJB11	PDIA6	ENSGALP00000010583	ENSGALP00000026487	J domain-containing protein.	Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.	0.918
DNAJB11	SDF2L1	ENSGALP00000010583	ENSGALP00000062678	J domain-containing protein.	Stromal cell derived factor 2 like 1.	0.806