| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE | AGT | ENSGALP00000039731 | ENSGALP00000018089 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Angiotensinogen; Belongs to the serpin family. | 0.985 |
| ACE | AGTR1 | ENSGALP00000039731 | ENSGALP00000057556 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.939 |
| ACE | AGTR2 | ENSGALP00000039731 | ENSGALP00000067208 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.764 |
| ACE | REN | ENSGALP00000039731 | ENSGALP00000000756 | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | Renin; Belongs to the peptidase A1 family. | 0.981 |
| AGT | ACE | ENSGALP00000018089 | ENSGALP00000039731 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.985 |
| AGT | AGTR1 | ENSGALP00000018089 | ENSGALP00000057556 | Angiotensinogen; Belongs to the serpin family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.999 |
| AGT | AGTR2 | ENSGALP00000018089 | ENSGALP00000067208 | Angiotensinogen; Belongs to the serpin family. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.996 |
| AGT | REN | ENSGALP00000018089 | ENSGALP00000000756 | Angiotensinogen; Belongs to the serpin family. | Renin; Belongs to the peptidase A1 family. | 0.975 |
| AGTR1 | ACE | ENSGALP00000057556 | ENSGALP00000039731 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.939 |
| AGTR1 | AGT | ENSGALP00000057556 | ENSGALP00000018089 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Angiotensinogen; Belongs to the serpin family. | 0.999 |
| AGTR1 | AGTR2 | ENSGALP00000057556 | ENSGALP00000067208 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.946 |
| AGTR1 | REN | ENSGALP00000057556 | ENSGALP00000000756 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | Renin; Belongs to the peptidase A1 family. | 0.846 |
| AGTR2 | ACE | ENSGALP00000067208 | ENSGALP00000039731 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.764 |
| AGTR2 | AGT | ENSGALP00000067208 | ENSGALP00000018089 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Angiotensinogen; Belongs to the serpin family. | 0.996 |
| AGTR2 | AGTR1 | ENSGALP00000067208 | ENSGALP00000057556 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.946 |
| AGTR2 | REN | ENSGALP00000067208 | ENSGALP00000000756 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | Renin; Belongs to the peptidase A1 family. | 0.506 |
| REN | ACE | ENSGALP00000000756 | ENSGALP00000039731 | Renin; Belongs to the peptidase A1 family. | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. | 0.981 |
| REN | AGT | ENSGALP00000000756 | ENSGALP00000018089 | Renin; Belongs to the peptidase A1 family. | Angiotensinogen; Belongs to the serpin family. | 0.975 |
| REN | AGTR1 | ENSGALP00000000756 | ENSGALP00000057556 | Renin; Belongs to the peptidase A1 family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. | 0.846 |
| REN | AGTR2 | ENSGALP00000000756 | ENSGALP00000067208 | Renin; Belongs to the peptidase A1 family. | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. | 0.506 |