10 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNAP25	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (209 aa)
	VAMP3	V-SNARE coiled-coil homology domain-containing protein. (104 aa)
	SYT1	Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. May play a role in dendrite formation by melanocytes; Belongs to the synaptotagmin family. (430 aa)
	CPLX2	Uncharacterized protein. (134 aa)
	STX1A	Syntaxin 1A; Belongs to the syntaxin family. (407 aa)
	STX2	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (288 aa)
	STXBP1	Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxins, components of the synaptic vesicle fusion machinery. May play a role in determining the specificity of intracellular fusion reactions (By similarity). Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
	VAMP2	V-SNARE coiled-coil homology domain-containing protein. (114 aa)
	VAMP1	V-SNARE coiled-coil homology domain-containing protein. (119 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPLX2	SNAP23	ENSGALP00000042773	ENSGALP00000014793	Uncharacterized protein.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.717
CPLX2	SNAP25	ENSGALP00000042773	ENSGALP00000014636	Uncharacterized protein.	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family.	0.943
CPLX2	STX1A	ENSGALP00000042773	ENSGALP00000044709	Uncharacterized protein.	Syntaxin 1A; Belongs to the syntaxin family.	0.790
CPLX2	STX2	ENSGALP00000042773	ENSGALP00000045060	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.790
CPLX2	SYT1	ENSGALP00000042773	ENSGALP00000042075	Uncharacterized protein.	Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. May play a role in dendrite formation by melanocytes; Belongs to the synaptotagmin family.	0.604
CPLX2	VAMP1	ENSGALP00000042773	ENSGALP00000073865	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.828
CPLX2	VAMP2	ENSGALP00000042773	ENSGALP00000053785	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.828
CPLX2	VAMP3	ENSGALP00000042773	ENSGALP00000034600	Uncharacterized protein.	V-SNARE coiled-coil homology domain-containing protein.	0.833
SNAP23	CPLX2	ENSGALP00000014793	ENSGALP00000042773	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Uncharacterized protein.	0.717
SNAP23	SNAP25	ENSGALP00000014793	ENSGALP00000014636	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family.	0.595
SNAP23	STX1A	ENSGALP00000014793	ENSGALP00000044709	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Syntaxin 1A; Belongs to the syntaxin family.	0.968
SNAP23	STX2	ENSGALP00000014793	ENSGALP00000045060	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.973
SNAP23	STXBP1	ENSGALP00000014793	ENSGALP00000052373	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxins, components of the synaptic vesicle fusion machinery. May play a role in determining the specificity of intracellular fusion reactions (By similarity). Belongs to the STXBP/unc-18/SEC1 family.	0.602
SNAP23	SYT1	ENSGALP00000014793	ENSGALP00000042075	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. May play a role in dendrite formation by melanocytes; Belongs to the synaptotagmin family.	0.544
SNAP23	VAMP1	ENSGALP00000014793	ENSGALP00000073865	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	V-SNARE coiled-coil homology domain-containing protein.	0.984
SNAP23	VAMP2	ENSGALP00000014793	ENSGALP00000053785	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	V-SNARE coiled-coil homology domain-containing protein.	0.993
SNAP23	VAMP3	ENSGALP00000014793	ENSGALP00000034600	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	V-SNARE coiled-coil homology domain-containing protein.	0.999
SNAP25	CPLX2	ENSGALP00000014636	ENSGALP00000042773	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family.	Uncharacterized protein.	0.943
SNAP25	SNAP23	ENSGALP00000014636	ENSGALP00000014793	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.595
SNAP25	STX1A	ENSGALP00000014636	ENSGALP00000044709	Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family.	Syntaxin 1A; Belongs to the syntaxin family.	0.997