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| | CHMP7 | Charged multivesicular body protein 7; ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway; Belongs to the SNF7 family. (448 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | CHMP4B | Charged multivesicular body protein 4b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). (227 aa) |
| | FAM168B | Family with sequence similarity 168 member B. (195 aa) |
| | LINGO1 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). (558 aa) |
| | C17orf75 | Chromosome 17 open reading frame 75. (287 aa) |
| | VPS37B | VPS37B subunit of ESCRT-I. (283 aa) |
| | CPD | Carboxypeptidase D. (1360 aa) |
| | CCNDBP1 | Cyclin D1 binding protein 1. (335 aa) |
| | LRP3 | LDL receptor related protein 3. (834 aa) |
| | OMG | Oligodendrocyte myelin glycoprotein. (434 aa) |
| | TSG101 | Uncharacterized protein. (390 aa) |
| | UEVLD | UEV domain-containing protein. (479 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate. (759 aa) |
| | SPG21 | AB hydrolase-1 domain-containing protein. (310 aa) |
| | UBAP1L | Uncharacterized protein. (428 aa) |
| | RTN4R | Reticulon 4 receptor. (483 aa) |
| | ANP32A | LRRcap domain-containing protein. (291 aa) |
| | CTDSPL2 | CTD small phosphatase-like protein 2; Probable phosphatase. (558 aa) |
| | ZFYVE19 | FYVE-type domain-containing protein. (420 aa) |
| | ZCRB1 | Uncharacterized protein. (216 aa) |
| | MFAP3L | Microfibril associated protein 3 like. (380 aa) |
| | SPAST | Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (613 aa) |
| | TECPR2 | Tectonin beta-propeller repeat containing 2. (1463 aa) |
| | RTN1 | Reticulon. (760 aa) |
| | VPS4B | Uncharacterized protein; Belongs to the AAA ATPase family. (438 aa) |
| | CHMP5 | Uncharacterized protein. (219 aa) |
| | TBC1D23 | TBC1 domain family member 23; Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (By similarity). Plays a role in brain development (By similarity). May act as a general inhibitor of innate immunity signaling (By similarity). (679 aa) |
| | CHMP2B | Charged multivesicular body protein 2b; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). (214 aa) |
| | REEP1 | Receptor expression-enhancing protein. (223 aa) |
| | VPS36 | Vacuolar protein sorting 36 homolog. (541 aa) |
| | CHMP1A | Uncharacterized protein. (196 aa) |
| | UBAP1 | Ubiquitin associated protein 1. (515 aa) |
| | SPG11 | SPG11 vesicle trafficking associated, spatacsin. (2425 aa) |
| | KIAA0319L | KIAA0319 like. (1141 aa) |
| | CHMP6 | Charged multivesicular body protein 6; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In the ESCRT-III complex, it probably serves as an accepto [...] (200 aa) |
| | ZFYVE26 | Zinc finger FYVE-type containing 26. (2561 aa) |
| | RLBP1 | CRAL-TRIO domain-containing protein. (321 aa) |
| | PDZD8 | PDZ domain containing 8. (1160 aa) |
| | ARL9 | ADP ribosylation factor like GTPase 9. (144 aa) |
| | STAM | Signal transducing adaptor molecule. (522 aa) |
| | FAM91A1 | Family with sequence similarity 91 member A1. (843 aa) |
| | MVB12A | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity). (267 aa) |
| | VPS25 | Vacuolar protein sorting 25 homolog. (174 aa) |
| | RHPN2 | Uncharacterized protein. (532 aa) |
| | ATL2 | Atlastin GTPase 2. (576 aa) |
| | VPS4A | Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa) |
| | CHMP4C | Uncharacterized protein. (220 aa) |
| | KBTBD2 | Kelch repeat and BTB domain containing 2. (623 aa) |
| | DGKA | Diacylglycerol kinase. (714 aa) |
| | FAM49A | Protein FAM49A; Belongs to the FAM49 family. (356 aa) |
| | CCPG1 | Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family. (801 aa) |
| | CHMP2A | Charged multivesicular body protein 2a; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). (220 aa) |
| | VPS37C | VPS37 C-terminal domain-containing protein. (370 aa) |
| | ENSGALP00000052503 | Uncharacterized protein. (508 aa) |
| | PDCD6IP | BRO1 domain-containing protein. (887 aa) |
| | LNPK | Lunapark, ER junction formation factor. (419 aa) |
| | RTN4 | Reticulon. (1159 aa) |
| | FAM134A | Uncharacterized protein. (559 aa) |
| | TMPRSS9 | Transmembrane serine protease 9; Belongs to the peptidase S1 family. (1127 aa) |
| | CHMP1B | Charged multivesicular body protein 1b; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. (199 aa) |
| | STAM2 | Signal transducing adapter molecule 2; Involved in intracellular signal transduction mediated by EGF. As a protein associated with focal adhesions and actin filaments, it may play a role in EGF receptor-stimulated cytoskeletal reorganization. The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity). (576 aa) |
| | NOLC1 | Nucleolar and coiled-body phosphoprotein 1. (696 aa) |
| | RALGAPA1 | Rap-GAP domain-containing protein. (2219 aa) |
| | ENSGALP00000057424 | GB1/RHD3-type G domain-containing protein. (658 aa) |
| | IST1 | IST1 factor associated with ESCRT-III. (366 aa) |
| | ATL1 | Atlastin GTPase 1. (558 aa) |
| | MIA3 | SH3 domain-containing protein. (1994 aa) |
| | VTA1 | Vesicle trafficking 1. (391 aa) |
| | LRRC57 | Uncharacterized protein. (238 aa) |
| | LOC107052389 | 4F5 domain-containing protein. (62 aa) |
| | PTPN23 | Uncharacterized protein. (64 aa) |
| | REEP4 | Receptor expression-enhancing protein. (179 aa) |
| | AWAT1 | Uncharacterized protein. (382 aa) |
| | RTN3 | Reticulon. (320 aa) |
| | ENSGALP00000067877 | Coiled-coil and C2 domain containing 1A. (519 aa) |
| | ARL16 | ADP ribosylation factor like GTPase 16. (205 aa) |
| | VPS13C | Vacuolar protein sorting 13 homolog C. (3587 aa) |
| | VPS37D | VPS37D subunit of ESCRT-I. (358 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (563 aa) |
| | CHMP3 | Uncharacterized protein. (241 aa) |
| | BROX | BRO1 domain and CAAX motif containing. (411 aa) |
| | SERF2 | 4F5 domain-containing protein. (59 aa) |
| | RETREG1 | Reticulophagy regulator 1. (365 aa) |
| | VPS37A | VPS37A subunit of ESCRT-I. (395 aa) |
| | RTN2 | Reticulon. (316 aa) |
| | MVB12B | Uncharacterized protein. (332 aa) |
| | ATRNL1 | Attractin like 1. (1383 aa) |
| | SPART | Spartin. (631 aa) |
| | USP21 | Ubiquitin specific peptidase 21; Belongs to the peptidase C19 family. (223 aa) |
| | ENSGALP00000074109 | Hr1 domain-containing protein. (124 aa) |
