(12 nodes) Mixed, incl. Reticulon, and Endoplasmic reticulum-autophagosome adaptor activity network (Gallus gallus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (613 aa)
	RTN1	Reticulon. (760 aa)
	REEP1	Receptor expression-enhancing protein. (223 aa)
	ATL2	Atlastin GTPase 2. (576 aa)
	CCPG1	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family. (801 aa)
	FAM134A	Uncharacterized protein. (559 aa)
	IST1	IST1 factor associated with ESCRT-III. (366 aa)
	ATL1	Atlastin GTPase 1. (558 aa)
	RTN3	Reticulon. (320 aa)
	RETREG1	Reticulophagy regulator 1. (365 aa)
	RTN2	Reticulon. (316 aa)
	SPART	Spartin. (631 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATL1	REEP1	ENSGALP00000060356	ENSGALP00000025409	Atlastin GTPase 1.	Receptor expression-enhancing protein.	0.819
ATL1	RETREG1	ENSGALP00000060356	ENSGALP00000072574	Atlastin GTPase 1.	Reticulophagy regulator 1.	0.483
ATL1	RTN1	ENSGALP00000060356	ENSGALP00000019567	Atlastin GTPase 1.	Reticulon.	0.806
ATL1	RTN2	ENSGALP00000060356	ENSGALP00000072720	Atlastin GTPase 1.	Reticulon.	0.812
ATL1	RTN3	ENSGALP00000060356	ENSGALP00000067653	Atlastin GTPase 1.	Reticulon.	0.701
ATL1	SPART	ENSGALP00000060356	ENSGALP00000073570	Atlastin GTPase 1.	Spartin.	0.705
ATL1	SPAST	ENSGALP00000060356	ENSGALP00000017259	Atlastin GTPase 1.	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...]	0.881
ATL2	REEP1	ENSGALP00000044940	ENSGALP00000025409	Atlastin GTPase 2.	Receptor expression-enhancing protein.	0.808
ATL2	RETREG1	ENSGALP00000044940	ENSGALP00000072574	Atlastin GTPase 2.	Reticulophagy regulator 1.	0.445
ATL2	RTN1	ENSGALP00000044940	ENSGALP00000019567	Atlastin GTPase 2.	Reticulon.	0.780
ATL2	RTN2	ENSGALP00000044940	ENSGALP00000072720	Atlastin GTPase 2.	Reticulon.	0.806
ATL2	RTN3	ENSGALP00000044940	ENSGALP00000067653	Atlastin GTPase 2.	Reticulon.	0.701
ATL2	SPART	ENSGALP00000044940	ENSGALP00000073570	Atlastin GTPase 2.	Spartin.	0.695
ATL2	SPAST	ENSGALP00000044940	ENSGALP00000017259	Atlastin GTPase 2.	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...]	0.841
CCPG1	FAM134A	ENSGALP00000049446	ENSGALP00000055184	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family.	Uncharacterized protein.	0.843
CCPG1	RETREG1	ENSGALP00000049446	ENSGALP00000072574	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family.	Reticulophagy regulator 1.	0.855
CCPG1	RTN1	ENSGALP00000049446	ENSGALP00000019567	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family.	Reticulon.	0.714
CCPG1	RTN2	ENSGALP00000049446	ENSGALP00000072720	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family.	Reticulon.	0.714
CCPG1	RTN3	ENSGALP00000049446	ENSGALP00000067653	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family.	Reticulon.	0.791
FAM134A	CCPG1	ENSGALP00000055184	ENSGALP00000049446	Uncharacterized protein.	Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family.	0.843