(13 nodes) Mixed, incl. Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2, and TSC-22 / Dip / Bun network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAP4K4	Mitogen-activated protein kinase kinase kinase kinase 4. (1319 aa)
	NRK	Uncharacterized protein. (1236 aa)
	NRBP1	Protein kinase domain-containing protein. (532 aa)
	TSC22D1-2	TSC22 domain family protein 1; May serve as a transcriptional repressor; Belongs to the TSC-22/Dip/Bun family. (988 aa)
	LANCL3	LanC like 3. (416 aa)
	TMEM130	Transmembrane protein 130. (425 aa)
	TSC22D1	TSC22 domain family protein 1. (193 aa)
	UBE2QL1	Ubiquitin conjugating enzyme E2 Q family like 1. (312 aa)
	MAP4K3	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (837 aa)
	CRISPLD1	Cysteine-rich secretory protein LCCL domain-containing 1. (513 aa)
	C12orf43	Chromosome 12 open reading frame 43. (266 aa)
	MAGI3	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes; Belongs to the MAGUK family. (1466 aa)
	TSC22D2	TSC22 domain family member 2. (831 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf43	LANCL3	ENSGALP00000063402	ENSGALP00000035860	Chromosome 12 open reading frame 43.	LanC like 3.	0.704
C12orf43	MAP4K3	ENSGALP00000063402	ENSGALP00000049086	Chromosome 12 open reading frame 43.	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	0.625
C12orf43	MAP4K4	ENSGALP00000063402	ENSGALP00000008090	Chromosome 12 open reading frame 43.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.422
C12orf43	NRK	ENSGALP00000063402	ENSGALP00000014575	Chromosome 12 open reading frame 43.	Uncharacterized protein.	0.420
C12orf43	TMEM130	ENSGALP00000063402	ENSGALP00000040272	Chromosome 12 open reading frame 43.	Transmembrane protein 130.	0.673
C12orf43	UBE2QL1	ENSGALP00000063402	ENSGALP00000044016	Chromosome 12 open reading frame 43.	Ubiquitin conjugating enzyme E2 Q family like 1.	0.745
CRISPLD1	TSC22D1	ENSGALP00000049718	ENSGALP00000041298	Cysteine-rich secretory protein LCCL domain-containing 1.	TSC22 domain family protein 1.	0.501
CRISPLD1	TSC22D1-2	ENSGALP00000049718	ENSGALP00000035712	Cysteine-rich secretory protein LCCL domain-containing 1.	TSC22 domain family protein 1; May serve as a transcriptional repressor; Belongs to the TSC-22/Dip/Bun family.	0.483
LANCL3	C12orf43	ENSGALP00000035860	ENSGALP00000063402	LanC like 3.	Chromosome 12 open reading frame 43.	0.704
LANCL3	MAP4K3	ENSGALP00000035860	ENSGALP00000049086	LanC like 3.	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	0.534
LANCL3	TMEM130	ENSGALP00000035860	ENSGALP00000040272	LanC like 3.	Transmembrane protein 130.	0.586
LANCL3	UBE2QL1	ENSGALP00000035860	ENSGALP00000044016	LanC like 3.	Ubiquitin conjugating enzyme E2 Q family like 1.	0.703
MAGI3	MAP4K4	ENSGALP00000070097	ENSGALP00000008090	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes; Belongs to the MAGUK family.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.514
MAGI3	NRK	ENSGALP00000070097	ENSGALP00000014575	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes; Belongs to the MAGUK family.	Uncharacterized protein.	0.514
MAP4K3	C12orf43	ENSGALP00000049086	ENSGALP00000063402	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	Chromosome 12 open reading frame 43.	0.625
MAP4K3	LANCL3	ENSGALP00000049086	ENSGALP00000035860	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	LanC like 3.	0.534
MAP4K3	TMEM130	ENSGALP00000049086	ENSGALP00000040272	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	Transmembrane protein 130.	0.499
MAP4K3	UBE2QL1	ENSGALP00000049086	ENSGALP00000044016	Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.	Ubiquitin conjugating enzyme E2 Q family like 1.	0.603
MAP4K4	C12orf43	ENSGALP00000008090	ENSGALP00000063402	Mitogen-activated protein kinase kinase kinase kinase 4.	Chromosome 12 open reading frame 43.	0.422
MAP4K4	MAGI3	ENSGALP00000008090	ENSGALP00000070097	Mitogen-activated protein kinase kinase kinase kinase 4.	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes; Belongs to the MAGUK family.	0.514