STRINGSTRING
GH GH GNRH1 GNRH1 LHCGR LHCGR FSHR FSHR LOC417800 LOC417800 FSHB FSHB PRL PRL GNRHR GNRHR CGNRH-R CGNRH-R GHR GHR LOC112530163 LOC112530163 CGA CGA PRLR PRLR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GHSomatotropin; Growth hormone plays an important role in growth control. (216 aa)
GNRH1GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; Belongs to the GnRH family. (92 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (728 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (704 aa)
LOC417800Uncharacterized protein. (225 aa)
FSHBFollicle stimulating hormone, beta polypeptide. (131 aa)
PRLProlactin. (229 aa)
GNRHRType 1/III gonadotropin-releasing hormone receptor hexahelical variant. (354 aa)
CGNRH-RG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GHRGrowth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway; Belongs to the type I cytokine receptor family. Type 1 subfamily. (646 aa)
LOC112530163SH2 domain-containing protein. (839 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin; Belongs to the type I cytokine receptor family. Type 1 subfamily. (831 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.