STRINGSTRING
ADRA1A ADRA1A ADRA1B ADRA1B RGR RGR GNA11 GNA11 CYSLTR1 CYSLTR1 GNG13 GNG13 ARHGEF12 ARHGEF12 GNAZ GNAZ HTR2B HTR2B ADCY9 ADCY9 DRD2 DRD2 LPAR3 LPAR3 ADRB1 ADRB1 OPN3 OPN3 RRH RRH ADCY2 ADCY2 GNAL GNAL GNA14 GNA14 GNAQ GNAQ GNG10 GNG10 LPAR1 LPAR1 ADCY3 ADCY3 OPN5 OPN5 HTR2A HTR2A ADRB3 ADRB3 ADRA2A ADRA2A GNG5 GNG5 GNG2 GNG2 GNAI1 GNAI1 PLCB1 PLCB1 ADCY6-2 ADCY6-2 GNB5 GNB5 ADRB2 ADRB2 GNB3 GNB3 TACR1 TACR1 LPAR4 LPAR4 PLCB2 PLCB2 GNGT2 GNGT2 RAPGEF4 RAPGEF4 ADCY1 ADCY1 ARHGEF11 ARHGEF11 GNA13 GNA13 ADRA1D ADRA1D LPAR2 LPAR2 GNG4 GNG4 TAC1 TAC1 GNB4 GNB4 GNAS GNAS GCGR GCGR ADCY7 ADCY7 PLCB4 PLCB4 GNA12 GNA12 RAPGEF3 RAPGEF3 HTR2C HTR2C ENSGALP00000069116 ENSGALP00000069116 ENSGALP00000069991 ENSGALP00000069991 LPAR5 LPAR5 CYSLTR2 CYSLTR2 ADCY6 ADCY6 GNAI2 GNAI2 OPN1LW OPN1LW GNG7 GNG7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADRA1AAdrenoceptor alpha 1A. (467 aa)
ADRA1BAdrenoceptor alpha 1B. (507 aa)
RGRG_PROTEIN_RECEP_F1_2 domain-containing protein. (295 aa)
GNA11Guanine nucleotide-binding protein G11 alpha-subunit. (359 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (425 aa)
GNG13G protein gamma domain-containing protein. (67 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
GNAZG protein subunit alpha z. (355 aa)
HTR2BSerotonin receptor subtype 2b. (462 aa)
ADCY9Adenylate cyclase type 9; Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. (1346 aa)
DRD2Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (361 aa)
ADRB1Adrenoceptor beta 1. (477 aa)
OPN3Opsin 3. (395 aa)
RRHG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (334 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1101 aa)
GNALUncharacterized protein. (379 aa)
GNA14Uncharacterized protein. (187 aa)
GNAQUncharacterized protein. (359 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1127 aa)
OPN5G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
HTR2A5-hydroxytryptamine (Serotonin) receptor 2A. (468 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (425 aa)
ADRA2AAdrenoceptor alpha 2A. (444 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GNAI1Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] (354 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
ADCY6-2Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1217 aa)
GNB5WD_REPEATS_REGION domain-containing protein. (353 aa)
ADRB2Adrenoceptor beta 2. (402 aa)
GNB3G protein subunit beta 3. (340 aa)
TACR1Substance P receptor; Belongs to the G-protein coupled receptor 1 family. (411 aa)
LPAR4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4. (1026 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11. (1785 aa)
GNA13G protein subunit alpha 13. (377 aa)
ADRA1DAdrenoceptor alpha 1D. (511 aa)
LPAR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
TAC1Tachykinin precursor 1. (114 aa)
GNB4G protein subunit beta 4. (340 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha XL. (417 aa)
GCGRUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (532 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
GNA12G protein subunit alpha 12. (287 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (1050 aa)
HTR2C5-hydroxytryptamine (Serotonin) receptor 2C. (472 aa)
ENSGALP00000069116Uncharacterized protein. (59 aa)
ENSGALP00000069991Uncharacterized protein. (109 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (370 aa)
CYSLTR2Cysteinyl leukotriene receptor 2. (310 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1132 aa)
GNAI2Guanine nucleotide-binding protein G(i) subunit alpha-2. (460 aa)
OPN1LWRed-sensitive opsin; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (362 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (390 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (30%) [HD]