(5 nodes) D5 dopamine receptor binding, and Regulator of G protein signalling-like domain network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1544 aa)
	ARHGEF11	Rho guanine nucleotide exchange factor 11. (1785 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	GNA12	G protein subunit alpha 12. (287 aa)
	ENSGALP00000069991	Uncharacterized protein. (109 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF11	ARHGEF12	ENSGALP00000054507	ENSGALP00000010766	Rho guanine nucleotide exchange factor 11.	Rho guanine nucleotide exchange factor 12.	0.910
ARHGEF11	ENSGALP00000069991	ENSGALP00000054507	ENSGALP00000069991	Rho guanine nucleotide exchange factor 11.	Uncharacterized protein.	0.556
ARHGEF11	GNA12	ENSGALP00000054507	ENSGALP00000068420	Rho guanine nucleotide exchange factor 11.	G protein subunit alpha 12.	0.953
ARHGEF11	GNA13	ENSGALP00000054507	ENSGALP00000055111	Rho guanine nucleotide exchange factor 11.	G protein subunit alpha 13.	0.963
ARHGEF12	ARHGEF11	ENSGALP00000010766	ENSGALP00000054507	Rho guanine nucleotide exchange factor 12.	Rho guanine nucleotide exchange factor 11.	0.910
ARHGEF12	ENSGALP00000069991	ENSGALP00000010766	ENSGALP00000069991	Rho guanine nucleotide exchange factor 12.	Uncharacterized protein.	0.556
ARHGEF12	GNA12	ENSGALP00000010766	ENSGALP00000068420	Rho guanine nucleotide exchange factor 12.	G protein subunit alpha 12.	0.953
ARHGEF12	GNA13	ENSGALP00000010766	ENSGALP00000055111	Rho guanine nucleotide exchange factor 12.	G protein subunit alpha 13.	0.964
ENSGALP00000069991	ARHGEF11	ENSGALP00000069991	ENSGALP00000054507	Uncharacterized protein.	Rho guanine nucleotide exchange factor 11.	0.556
ENSGALP00000069991	ARHGEF12	ENSGALP00000069991	ENSGALP00000010766	Uncharacterized protein.	Rho guanine nucleotide exchange factor 12.	0.556
ENSGALP00000069991	GNA12	ENSGALP00000069991	ENSGALP00000068420	Uncharacterized protein.	G protein subunit alpha 12.	0.965
ENSGALP00000069991	GNA13	ENSGALP00000069991	ENSGALP00000055111	Uncharacterized protein.	G protein subunit alpha 13.	0.726
GNA12	ARHGEF11	ENSGALP00000068420	ENSGALP00000054507	G protein subunit alpha 12.	Rho guanine nucleotide exchange factor 11.	0.953
GNA12	ARHGEF12	ENSGALP00000068420	ENSGALP00000010766	G protein subunit alpha 12.	Rho guanine nucleotide exchange factor 12.	0.953
GNA12	ENSGALP00000069991	ENSGALP00000068420	ENSGALP00000069991	G protein subunit alpha 12.	Uncharacterized protein.	0.965
GNA12	GNA13	ENSGALP00000068420	ENSGALP00000055111	G protein subunit alpha 12.	G protein subunit alpha 13.	0.939
GNA13	ARHGEF11	ENSGALP00000055111	ENSGALP00000054507	G protein subunit alpha 13.	Rho guanine nucleotide exchange factor 11.	0.963
GNA13	ARHGEF12	ENSGALP00000055111	ENSGALP00000010766	G protein subunit alpha 13.	Rho guanine nucleotide exchange factor 12.	0.964
GNA13	ENSGALP00000069991	ENSGALP00000055111	ENSGALP00000069991	G protein subunit alpha 13.	Uncharacterized protein.	0.726
GNA13	GNA12	ENSGALP00000055111	ENSGALP00000068420	G protein subunit alpha 13.	G protein subunit alpha 12.	0.939