(5 nodes) Citrate synthase, and Malate dehydrogenase, active site network (Gallus gallus)

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Your Input:
	MDH2	Malate dehydrogenase. (337 aa)
	MDH1	Malate dehydrogenase, cytoplasmic. (535 aa)
	CS	Citrate synthase, mitochondrial. (467 aa)
	ACLY	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1101 aa)
	PCK2	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver. (414 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	CS	ENSGALP00000055831	ENSGALP00000053792	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	Citrate synthase, mitochondrial.	0.997
ACLY	MDH1	ENSGALP00000055831	ENSGALP00000014374	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	Malate dehydrogenase, cytoplasmic.	0.972
ACLY	MDH2	ENSGALP00000055831	ENSGALP00000003012	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	Malate dehydrogenase.	0.981
ACLY	PCK2	ENSGALP00000055831	ENSGALP00000071013	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	0.955
CS	ACLY	ENSGALP00000053792	ENSGALP00000055831	Citrate synthase, mitochondrial.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.997
CS	MDH1	ENSGALP00000053792	ENSGALP00000014374	Citrate synthase, mitochondrial.	Malate dehydrogenase, cytoplasmic.	0.989
CS	MDH2	ENSGALP00000053792	ENSGALP00000003012	Citrate synthase, mitochondrial.	Malate dehydrogenase.	0.999
CS	PCK2	ENSGALP00000053792	ENSGALP00000071013	Citrate synthase, mitochondrial.	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	0.964
MDH1	ACLY	ENSGALP00000014374	ENSGALP00000055831	Malate dehydrogenase, cytoplasmic.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.972
MDH1	CS	ENSGALP00000014374	ENSGALP00000053792	Malate dehydrogenase, cytoplasmic.	Citrate synthase, mitochondrial.	0.989
MDH1	MDH2	ENSGALP00000014374	ENSGALP00000003012	Malate dehydrogenase, cytoplasmic.	Malate dehydrogenase.	0.982
MDH1	PCK2	ENSGALP00000014374	ENSGALP00000071013	Malate dehydrogenase, cytoplasmic.	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	0.962
MDH2	ACLY	ENSGALP00000003012	ENSGALP00000055831	Malate dehydrogenase.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.981
MDH2	CS	ENSGALP00000003012	ENSGALP00000053792	Malate dehydrogenase.	Citrate synthase, mitochondrial.	0.999
MDH2	MDH1	ENSGALP00000003012	ENSGALP00000014374	Malate dehydrogenase.	Malate dehydrogenase, cytoplasmic.	0.982
MDH2	PCK2	ENSGALP00000003012	ENSGALP00000071013	Malate dehydrogenase.	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	0.947
PCK2	ACLY	ENSGALP00000071013	ENSGALP00000055831	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.	0.955
PCK2	CS	ENSGALP00000071013	ENSGALP00000053792	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	Citrate synthase, mitochondrial.	0.964
PCK2	MDH1	ENSGALP00000071013	ENSGALP00000014374	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	Malate dehydrogenase, cytoplasmic.	0.962
PCK2	MDH2	ENSGALP00000071013	ENSGALP00000003012	Phosphoenolpyruvate carboxykinase [GTP], mitochondrial; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Facilitates the recycling of lactate carbon in the liver.	Malate dehydrogenase.	0.947