(12 nodes) Propanoate metabolism, and Thiolase, N-terminal domain network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (662 aa)
	ACAA1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (432 aa)
	ALDH6A1	Aldehyde dehydrogenase 6 family member A1. (506 aa)
	ACSS1B	Acetyl-coenzyme A synthetase. (682 aa)
	PCCA	Propionyl-CoA carboxylase subunit alpha. (713 aa)
	ACSS3	Acyl-CoA synthetase short chain family member 3. (668 aa)
	PCCB	Propionyl-CoA carboxylase subunit beta. (529 aa)
	ACAA2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (423 aa)
	ACADS	Uncharacterized protein. (489 aa)
	HADH	Uncharacterized protein. (350 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family. (300 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (726 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACAA2	ENSGALP00000009408	ENSGALP00000053550	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.924
ACAA1	ACADS	ENSGALP00000009408	ENSGALP00000060731	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.983
ACAA1	ACOX1	ENSGALP00000009408	ENSGALP00000003376	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.994
ACAA1	ACSS1B	ENSGALP00000009408	ENSGALP00000016604	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coenzyme A synthetase.	0.894
ACAA1	ACSS3	ENSGALP00000009408	ENSGALP00000037606	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase short chain family member 3.	0.899
ACAA1	ALDH6A1	ENSGALP00000009408	ENSGALP00000016585	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Aldehyde dehydrogenase 6 family member A1.	0.950
ACAA1	ECHDC1	ENSGALP00000009408	ENSGALP00000070409	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family.	0.977
ACAA1	EHHADH	ENSGALP00000009408	ENSGALP00000072226	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.997
ACAA1	HADH	ENSGALP00000009408	ENSGALP00000061622	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.993
ACAA1	PCCA	ENSGALP00000009408	ENSGALP00000027209	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Propionyl-CoA carboxylase subunit alpha.	0.936
ACAA1	PCCB	ENSGALP00000009408	ENSGALP00000045840	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Propionyl-CoA carboxylase subunit beta.	0.947
ACAA2	ACAA1	ENSGALP00000053550	ENSGALP00000009408	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.924
ACAA2	ACADS	ENSGALP00000053550	ENSGALP00000060731	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.982
ACAA2	ACOX1	ENSGALP00000053550	ENSGALP00000003376	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.977
ACAA2	ACSS1B	ENSGALP00000053550	ENSGALP00000016604	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coenzyme A synthetase.	0.915
ACAA2	ACSS3	ENSGALP00000053550	ENSGALP00000037606	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase short chain family member 3.	0.896
ACAA2	ALDH6A1	ENSGALP00000053550	ENSGALP00000016585	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Aldehyde dehydrogenase 6 family member A1.	0.949
ACAA2	ECHDC1	ENSGALP00000053550	ENSGALP00000070409	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family.	0.977
ACAA2	EHHADH	ENSGALP00000053550	ENSGALP00000072226	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.986
ACAA2	HADH	ENSGALP00000053550	ENSGALP00000061622	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.992