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SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa) | ||||
RNF113B | Zinc finger protein 183. (328 aa) | ||||
SF3A2 | Splicing factor 3a subunit 2. (315 aa) | ||||
SYF2 | Uncharacterized protein. (252 aa) | ||||
SF3A3 | Splicing factor 3a subunit 3. (501 aa) | ||||
CWC25 | CWC25 spliceosome associated protein homolog. (416 aa) | ||||
BCAS2 | Uncharacterized protein. (225 aa) | ||||
SNIP1 | Smad nuclear interacting protein 1. (364 aa) | ||||
SF3B3 | Splicing factor 3b subunit 3. (1217 aa) | ||||
SNRPC | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (160 aa) | ||||
PRPF8 | Pre-mRNA processing factor 8. (2335 aa) | ||||
RBM22 | Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Belongs to the SLT11 family. (420 aa) | ||||
BUD31 | BUD31 homolog. (144 aa) | ||||
PPIH | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa) | ||||
ISY1 | Uncharacterized protein. (280 aa) | ||||
PRPF6 | Pre-mRNA processing factor 6. (941 aa) | ||||
SNRPD3 | Small nuclear ribonucleoprotein Sm D3. (126 aa) | ||||
SNRPA1 | LRRcap domain-containing protein. (255 aa) | ||||
SF3A1 | Uncharacterized protein. (790 aa) | ||||
SF3B1 | Splicing factor 3b subunit 1. (1301 aa) | ||||
CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (686 aa) | ||||
PRPF4 | Pre-mRNA processing factor 4. (537 aa) | ||||
CWC22 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. (926 aa) | ||||
TCERG1L | Transcription elongation regulator 1 like. (577 aa) | ||||
SNW1 | SNW domain containing 1. (538 aa) | ||||
PRPF38A | PRP38_assoc domain-containing protein. (312 aa) | ||||
PHF5A | Uncharacterized protein. (110 aa) | ||||
SF3B4 | Splicing factor 3b subunit 4. (418 aa) | ||||
CDC40 | WD_REPEATS_REGION domain-containing protein. (580 aa) | ||||
TXNL4B | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa) | ||||
SF3B6 | Splicing factor 3b subunit 6. (91 aa) | ||||
DHX38 | Uncharacterized protein. (1230 aa) | ||||
PRPF3 | U4/U6 small nuclear ribonucleoprotein Prp3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). (684 aa) | ||||
NWD1 | WD_REPEATS_REGION domain-containing protein. (425 aa) | ||||
MFAP1 | Microfibrillar-associated protein 1; Involved in pre-mRNA splicing as a component of the spliceosome; Belongs to the MFAP1 family. (439 aa) | ||||
SNRPB2 | Small nuclear ribonucleoprotein polypeptide B2. (226 aa) | ||||
YJU2 | YJU2 splicing factor homolog. (421 aa) | ||||
BUD13 | BUD13 homolog. (770 aa) | ||||
SNRPN | Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa) | ||||
SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) | ||||
SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa) | ||||
PRPF18 | SFM domain-containing protein. (351 aa) | ||||
DDX23 | DEAD-box helicase 23. (816 aa) | ||||
SNRNP200 | Helicase_PWI domain-containing protein. (614 aa) | ||||
PPRC1 | PPARG related coactivator 1. (1680 aa) | ||||
ZMAT2 | U1-type domain-containing protein. (199 aa) | ||||
SLU7 | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. (671 aa) | ||||
PLRG1 | Pleiotropic regulator 1. (516 aa) | ||||
CWC15 | Uncharacterized protein. (230 aa) | ||||
SNRPF | Sm domain-containing protein. (86 aa) | ||||
CWC27 | CWC27 spliceosome associated cyclophilin. (477 aa) | ||||
EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). (1222 aa) | ||||
TXNL4A | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) | ||||
CDC5L | Cell division cycle 5 like. (1410 aa) | ||||
LOC107052453 | LRRcap domain-containing protein. (320 aa) | ||||
ENSGALP00000065976 | Cwf21 domain-containing protein. (255 aa) | ||||
ENSGALP00000066377 | Helicase C-terminal domain-containing protein. (528 aa) | ||||
SNRPGP15 | Small nuclear ribonucleoprotein G. (76 aa) | ||||
LRMDA | Leucine rich melanocyte differentiation associated. (168 aa) | ||||
RBMX2 | RRM domain-containing protein. (253 aa) | ||||
LOC112530170 | SEC63 domain-containing protein. (235 aa) | ||||
SNRNP35 | RRM domain-containing protein. (263 aa) | ||||
ENSGALP00000070086 | Uncharacterized protein. (597 aa) | ||||
SNRPD2 | Small nuclear ribonucleoprotein Sm D2. (146 aa) |