STRINGSTRING
SNRPE SNRPE RNF113B RNF113B SF3A2 SF3A2 SYF2 SYF2 SF3A3 SF3A3 CWC25 CWC25 BCAS2 BCAS2 SNIP1 SNIP1 SF3B3 SF3B3 SNRPC SNRPC PRPF8 PRPF8 RBM22 RBM22 BUD31 BUD31 PPIH PPIH ISY1 ISY1 PRPF6 PRPF6 SNRPD3 SNRPD3 SNRPA1 SNRPA1 SF3A1 SF3A1 SF3B1 SF3B1 CRNKL1 CRNKL1 PRPF4 PRPF4 CWC22 CWC22 TCERG1L TCERG1L SNW1 SNW1 PRPF38A PRPF38A PHF5A PHF5A SF3B4 SF3B4 CDC40 CDC40 TXNL4B TXNL4B SF3B6 SF3B6 DHX38 DHX38 PRPF3 PRPF3 NWD1 NWD1 MFAP1 MFAP1 SNRPB2 SNRPB2 YJU2 YJU2 BUD13 BUD13 SNRPN SNRPN SF3B5 SF3B5 SNRPD1 SNRPD1 PRPF18 PRPF18 DDX23 DDX23 SNRNP200 SNRNP200 PPRC1 PPRC1 ZMAT2 ZMAT2 SLU7 SLU7 PLRG1 PLRG1 CWC15 CWC15 SNRPF SNRPF CWC27 CWC27 EFTUD2 EFTUD2 TXNL4A TXNL4A CDC5L CDC5L LOC107052453 LOC107052453 ENSGALP00000065976 ENSGALP00000065976 ENSGALP00000066377 ENSGALP00000066377 SNRPGP15 SNRPGP15 LRMDA LRMDA RBMX2 RBMX2 LOC112530170 LOC112530170 SNRNP35 SNRNP35 ENSGALP00000070086 ENSGALP00000070086 SNRPD2 SNRPD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa)
RNF113BZinc finger protein 183. (328 aa)
SF3A2Splicing factor 3a subunit 2. (315 aa)
SYF2Uncharacterized protein. (252 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
CWC25CWC25 spliceosome associated protein homolog. (416 aa)
BCAS2Uncharacterized protein. (225 aa)
SNIP1Smad nuclear interacting protein 1. (364 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
SNRPCU1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (160 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
RBM22Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Belongs to the SLT11 family. (420 aa)
BUD31BUD31 homolog. (144 aa)
PPIHPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (177 aa)
ISY1Uncharacterized protein. (280 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3. (126 aa)
SNRPA1LRRcap domain-containing protein. (255 aa)
SF3A1Uncharacterized protein. (790 aa)
SF3B1Splicing factor 3b subunit 1. (1301 aa)
CRNKL1Crooked neck pre-mRNA splicing factor 1. (686 aa)
PRPF4Pre-mRNA processing factor 4. (537 aa)
CWC22Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. (926 aa)
TCERG1LTranscription elongation regulator 1 like. (577 aa)
SNW1SNW domain containing 1. (538 aa)
PRPF38APRP38_assoc domain-containing protein. (312 aa)
PHF5AUncharacterized protein. (110 aa)
SF3B4Splicing factor 3b subunit 4. (418 aa)
CDC40WD_REPEATS_REGION domain-containing protein. (580 aa)
TXNL4BThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
SF3B6Splicing factor 3b subunit 6. (91 aa)
DHX38Uncharacterized protein. (1230 aa)
PRPF3U4/U6 small nuclear ribonucleoprotein Prp3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). (684 aa)
NWD1WD_REPEATS_REGION domain-containing protein. (425 aa)
MFAP1Microfibrillar-associated protein 1; Involved in pre-mRNA splicing as a component of the spliceosome; Belongs to the MFAP1 family. (439 aa)
SNRPB2Small nuclear ribonucleoprotein polypeptide B2. (226 aa)
YJU2YJU2 splicing factor homolog. (421 aa)
BUD13BUD13 homolog. (770 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
PRPF18SFM domain-containing protein. (351 aa)
DDX23DEAD-box helicase 23. (816 aa)
SNRNP200Helicase_PWI domain-containing protein. (614 aa)
PPRC1PPARG related coactivator 1. (1680 aa)
ZMAT2U1-type domain-containing protein. (199 aa)
SLU7Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. (671 aa)
PLRG1Pleiotropic regulator 1. (516 aa)
CWC15Uncharacterized protein. (230 aa)
SNRPFSm domain-containing protein. (86 aa)
CWC27CWC27 spliceosome associated cyclophilin. (477 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). (1222 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
CDC5LCell division cycle 5 like. (1410 aa)
LOC107052453LRRcap domain-containing protein. (320 aa)
ENSGALP00000065976Cwf21 domain-containing protein. (255 aa)
ENSGALP00000066377Helicase C-terminal domain-containing protein. (528 aa)
SNRPGP15Small nuclear ribonucleoprotein G. (76 aa)
LRMDALeucine rich melanocyte differentiation associated. (168 aa)
RBMX2RRM domain-containing protein. (253 aa)
LOC112530170SEC63 domain-containing protein. (235 aa)
SNRNP35RRM domain-containing protein. (263 aa)
ENSGALP00000070086Uncharacterized protein. (597 aa)
SNRPD2Small nuclear ribonucleoprotein Sm D2. (146 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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