(11 nodes) Anaphase-promoting complex network (Gallus gallus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC27	Uncharacterized protein. (833 aa)
	CDC23	Cell division cycle 23. (595 aa)
	CDC16	TPR_REGION domain-containing protein. (623 aa)
	ANAPC5	Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). (756 aa)
	ANAPC4	Anaphase promoting complex subunit 4. (838 aa)
	ANAPC13	Uncharacterized protein. (74 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (884 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1948 aa)
	ANAPC10	DOC domain-containing protein. (255 aa)
	ENSGALP00000071775	RING-type domain-containing protein. (343 aa)
	CDC26	Uncharacterized protein. (84 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANAPC1	ANAPC10	ENSGALP00000067663	ENSGALP00000071134	Anaphase promoting complex subunit 1.	DOC domain-containing protein.	0.998
ANAPC1	ANAPC13	ENSGALP00000067663	ENSGALP00000057085	Anaphase promoting complex subunit 1.	Uncharacterized protein.	0.984
ANAPC1	ANAPC2	ENSGALP00000067663	ENSGALP00000061380	Anaphase promoting complex subunit 1.	Anaphase promoting complex subunit 2; Belongs to the cullin family.	0.998
ANAPC1	ANAPC4	ENSGALP00000067663	ENSGALP00000049992	Anaphase promoting complex subunit 1.	Anaphase promoting complex subunit 4.	0.998
ANAPC1	ANAPC5	ENSGALP00000067663	ENSGALP00000038461	Anaphase promoting complex subunit 1.	Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).	0.998
ANAPC1	CDC16	ENSGALP00000067663	ENSGALP00000027097	Anaphase promoting complex subunit 1.	TPR_REGION domain-containing protein.	0.998
ANAPC1	CDC23	ENSGALP00000067663	ENSGALP00000012291	Anaphase promoting complex subunit 1.	Cell division cycle 23.	0.998
ANAPC1	CDC26	ENSGALP00000067663	ENSGALP00000072219	Anaphase promoting complex subunit 1.	Uncharacterized protein.	0.986
ANAPC1	CDC27	ENSGALP00000067663	ENSGALP00000000830	Anaphase promoting complex subunit 1.	Uncharacterized protein.	0.998
ANAPC1	ENSGALP00000071775	ENSGALP00000067663	ENSGALP00000071775	Anaphase promoting complex subunit 1.	RING-type domain-containing protein.	0.998
ANAPC10	ANAPC1	ENSGALP00000071134	ENSGALP00000067663	DOC domain-containing protein.	Anaphase promoting complex subunit 1.	0.998
ANAPC10	ANAPC13	ENSGALP00000071134	ENSGALP00000057085	DOC domain-containing protein.	Uncharacterized protein.	0.998
ANAPC10	ANAPC2	ENSGALP00000071134	ENSGALP00000061380	DOC domain-containing protein.	Anaphase promoting complex subunit 2; Belongs to the cullin family.	0.999
ANAPC10	ANAPC4	ENSGALP00000071134	ENSGALP00000049992	DOC domain-containing protein.	Anaphase promoting complex subunit 4.	0.998
ANAPC10	ANAPC5	ENSGALP00000071134	ENSGALP00000038461	DOC domain-containing protein.	Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).	0.998
ANAPC10	CDC16	ENSGALP00000071134	ENSGALP00000027097	DOC domain-containing protein.	TPR_REGION domain-containing protein.	0.998
ANAPC10	CDC23	ENSGALP00000071134	ENSGALP00000012291	DOC domain-containing protein.	Cell division cycle 23.	0.998
ANAPC10	CDC26	ENSGALP00000071134	ENSGALP00000072219	DOC domain-containing protein.	Uncharacterized protein.	0.998
ANAPC10	CDC27	ENSGALP00000071134	ENSGALP00000000830	DOC domain-containing protein.	Uncharacterized protein.	0.998
ANAPC10	ENSGALP00000071775	ENSGALP00000071134	ENSGALP00000071775	DOC domain-containing protein.	RING-type domain-containing protein.	0.998