(5 nodes) Protein deneddylation network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COPS2	PCI domain-containing protein. (443 aa)
	COPS4	PCI domain-containing protein. (411 aa)
	COPS5	MPN domain-containing protein. (337 aa)
	COPS8	PCI domain-containing protein. (230 aa)
	COPS3	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity). (423 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPS2	COPS3	ENSGALP00000000549	ENSGALP00000064004	PCI domain-containing protein.	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	0.999
COPS2	COPS4	ENSGALP00000000549	ENSGALP00000018122	PCI domain-containing protein.	PCI domain-containing protein.	0.999
COPS2	COPS5	ENSGALP00000000549	ENSGALP00000043615	PCI domain-containing protein.	MPN domain-containing protein.	0.999
COPS2	COPS8	ENSGALP00000000549	ENSGALP00000048257	PCI domain-containing protein.	PCI domain-containing protein.	0.999
COPS3	COPS2	ENSGALP00000064004	ENSGALP00000000549	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	PCI domain-containing protein.	0.999
COPS3	COPS4	ENSGALP00000064004	ENSGALP00000018122	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	PCI domain-containing protein.	0.999
COPS3	COPS5	ENSGALP00000064004	ENSGALP00000043615	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	MPN domain-containing protein.	0.999
COPS3	COPS8	ENSGALP00000064004	ENSGALP00000048257	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	PCI domain-containing protein.	0.999
COPS4	COPS2	ENSGALP00000018122	ENSGALP00000000549	PCI domain-containing protein.	PCI domain-containing protein.	0.999
COPS4	COPS3	ENSGALP00000018122	ENSGALP00000064004	PCI domain-containing protein.	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	0.999
COPS4	COPS5	ENSGALP00000018122	ENSGALP00000043615	PCI domain-containing protein.	MPN domain-containing protein.	0.999
COPS4	COPS8	ENSGALP00000018122	ENSGALP00000048257	PCI domain-containing protein.	PCI domain-containing protein.	0.999
COPS5	COPS2	ENSGALP00000043615	ENSGALP00000000549	MPN domain-containing protein.	PCI domain-containing protein.	0.999
COPS5	COPS3	ENSGALP00000043615	ENSGALP00000064004	MPN domain-containing protein.	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	0.999
COPS5	COPS4	ENSGALP00000043615	ENSGALP00000018122	MPN domain-containing protein.	PCI domain-containing protein.	0.999
COPS5	COPS8	ENSGALP00000043615	ENSGALP00000048257	MPN domain-containing protein.	PCI domain-containing protein.	0.998
COPS8	COPS2	ENSGALP00000048257	ENSGALP00000000549	PCI domain-containing protein.	PCI domain-containing protein.	0.999
COPS8	COPS3	ENSGALP00000048257	ENSGALP00000064004	PCI domain-containing protein.	COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity).	0.999
COPS8	COPS4	ENSGALP00000048257	ENSGALP00000018122	PCI domain-containing protein.	PCI domain-containing protein.	0.999
COPS8	COPS5	ENSGALP00000048257	ENSGALP00000043615	PCI domain-containing protein.	MPN domain-containing protein.	0.998