STRINGSTRING
PANX2 PANX2 PPFIA4 PPFIA4 KCNC4 KCNC4 KCNA10 KCNA10 SLC1A6 SLC1A6 GJC3 GJC3 NSF NSF KCNJ1 KCNJ1 KCNJ5 KCNJ5 HCN2 HCN2 KCND3 KCND3 GABRB2 GABRB2 GABRA6 GABRA6 GABRA1 GABRA1 GRIK3 GRIK3 UNC13B UNC13B KCNN2 KCNN2 CHRNA3 CHRNA3 HOMER3-2 HOMER3-2 KCNS1 KCNS1 SLC6A4 SLC6A4 KCNJ16 KCNJ16 KCNJ12 KCNJ12 LOC107057078 LOC107057078 SLC6A11 SLC6A11 GNG13 GNG13 CAMK2A CAMK2A CHRNA4 CHRNA4 HOMER2 HOMER2 ABCC8 ABCC8 KCNC1 KCNC1 PRKAR2A PRKAR2A RPS6KA6 RPS6KA6 SLITRK4 SLITRK4 GABRA3 GABRA3 GRIN2A GRIN2A KCNG1 KCNG1 PRKAR2B PRKAR2B GNAT3 GNAT3 AP2M1 AP2M1 CREB1 CREB1 CACNB2 CACNB2 IL1RAPL2 IL1RAPL2 SNAP25 SNAP25 KCND2 KCND2 SLITRK2 SLITRK2 KCNK18 KCNK18 SLC18A2 SLC18A2 GLRB GLRB KCNK2 KCNK2 SLC38A1 SLC38A1 GJD2 GJD2 KCNG3 KCNG3 KCNMB4 KCNMB4 LRFN2 LRFN2 KCNK16 KCNK16 KCNK17 KCNK17 KCNV2 KCNV2 SLC1A1 SLC1A1 KCNK10 KCNK10 LIN7A LIN7A KCNK1 KCNK1 KCNH8 KCNH8 SLC22A2 SLC22A2 GRIN2B GRIN2B KCNH5 KCNH5 KCNJ4 KCNJ4 GRM1 GRM1 SLC6A12 SLC6A12 SLC6A13 SLC6A13 ADCY2 ADCY2 GNAL GNAL GABRA4 GABRA4 GABRA2 GABRA2 CHRNA9 CHRNA9 HCN1 HCN1 CPLX1 CPLX1 GRIK2 GRIK2 GRIN3A GRIN3A GJA10 GJA10 GNG10 GNG10 GABRR2 GABRR2 GABRR1 GABRR1 KCNJ15 KCNJ15 MAOA MAOA TSPAN7 TSPAN7 IL1RAPL1 IL1RAPL1 KCNF1 KCNF1 KCNS3 KCNS3 GLRA2 GLRA2 ADCY3 ADCY3 GABRA5 GABRA5 SLC5A7 SLC5A7 SLITRK1 SLITRK1 GRM5 GRM5 KCNJ11 KCNJ11 CAMK2G CAMK2G KCNG4 KCNG4 KCNB1 KCNB1 GLRA1 GLRA1 PRKAR1A PRKAR1A NAAA NAAA GRIA2 GRIA2 LIN7C LIN7C GRIN1 GRIN1 GNB1 GNB1 KCNA2 KCNA2 GRIN2C GRIN2C PRKCA PRKCA NLGN3 NLGN3 PRKACB PRKACB SYT1 SYT1 KCNJ8 KCNJ8 GNG5 GNG5 GNG2 GNG2 CACNG4 CACNG4 PPFIBP2 PPFIBP2 AP2A2 AP2A2 STX1A STX1A RPS6KA3 RPS6KA3 KCNMB2 KCNMB2 SLC18A3 SLC18A3 PLCB1 PLCB1 KCNAB2 KCNAB2 PANX1 PANX1 ADCY6-2 ADCY6-2 PPFIA1 PPFIA1 GABBR2 GABBR2 KCNH1 KCNH1 NLGN1 NLGN1 DLG1 DLG1 KCNK13 KCNK13 CACNA1E CACNA1E DLGAP4 DLGAP4 SLC6A1 SLC6A1 PICK1 PICK1 SLC1A7 SLC1A7 KCNH7 KCNH7 GNB5 GNB5 CASK CASK KCNQ5 KCNQ5 AP2B1 AP2B1 GNB3 GNB3 RAB3A RAB3A KCNV1 KCNV1 NTRK3 NTRK3 DLGAP1 DLGAP1 GABRB3 GABRB3 LRTOMT LRTOMT GRIP2 GRIP2 LRRC7 LRRC7 RPS6KA1 RPS6KA1 SHANK2 SHANK2 KCNS2 KCNS2 PRKAR1B PRKAR1B PPFIA2 PPFIA2 KCNN3 KCNN3 KCNK9 KCNK9 CACNA2D2 CACNA2D2 PLCB2 PLCB2 CACNB4 CACNB4 CAMK2B CAMK2B GLRA3 GLRA3 KCNA4 KCNA4 DLGAP3 DLGAP3 PTPRD PTPRD ALDH5A1 ALDH5A1 GRIK1 GRIK1 KCNA3 KCNA3 KCNB2 KCNB2 GNG12 GNG12 GRIA1 GRIA1 ENSGALP00000052914 ENSGALP00000052914 GRIA3 GRIA3 GRIA4 GRIA4 GAD1 GAD1 SLITRK3 SLITRK3 GABRG2 GABRG2 GNGT2 GNGT2 KCNQ4 KCNQ4 ADCY1 ADCY1 ADCY8 ADCY8 GLS2 GLS2 ACTN2 ACTN2 SLC32A1 SLC32A1 KCNA6 KCNA6 GAD2 GAD2 SLC1A2 SLC1A2 DLGAP2 DLGAP2 HOMER1 HOMER1 PRKCB PRKCB KCNK3 KCNK3 KCNG2 KCNG2 PTPRF PTPRF GABRG3 GABRG3 HCN3 HCN3 GABRQ GABRQ KCNC2 KCNC2 GNG4 GNG4 KCNAB1 KCNAB1 SLITRK6 SLITRK6 NEFL NEFL GNAI3 GNAI3 KCNMA1 KCNMA1 KCNA5 KCNA5 ARHGEF9 ARHGEF9 GNB4 GNB4 CACNB1 CACNB1 KCNC3 KCNC3 EPB41L1 EPB41L1 SH3GLB2 SH3GLB2 AP2S1 AP2S1 EPB41L3 EPB41L3 NLGN2 NLGN2 KCNJ6 KCNJ6 CACNA2D3 CACNA2D3 APBA1 APBA1 ADCY7 ADCY7 ABAT ABAT KCNMB1 KCNMB1 GRIP1 GRIP1 CACNB3 CACNB3 BCHE BCHE DLG3 DLG3 ABCC9 ABCC9 NLGN4Y NLGN4Y LOC415787 LOC415787 PPFIBP1 PPFIBP1 COMT COMT KCNH2 KCNH2 ENSGALP00000070753 ENSGALP00000070753 KCNH4 KCNH4 TSPOAP1 TSPOAP1 RPS6KA2 RPS6KA2 KCNQ1 KCNQ1 LRFN1 LRFN1 KCNQ2 KCNQ2 ADCY6 ADCY6 FLOT1 FLOT1 KCNN1 KCNN1 IL1RAP IL1RAP EPB41L5 EPB41L5 SLC1A3 SLC1A3 KCNQ3 KCNQ3 GNG7 GNG7
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PANX2Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (678 aa)
PPFIA4PTPRF interacting protein alpha 4. (1205 aa)
KCNC4Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (611 aa)
KCNA10Potassium voltage-gated channel subfamily A member 10; Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP (By similarity). (516 aa)
SLC1A6Amino acid transporter. (546 aa)
GJC3Gap junction gamma-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Gamma-type subfamily. (394 aa)
NSFUncharacterized protein. (740 aa)
KCNJ1Potassium voltage-gated channel subfamily J member 1. (388 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (442 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (906 aa)
KCND3BTB domain-containing protein; Belongs to the potassium channel family. (658 aa)
GABRB2Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (491 aa)
GABRA6Gamma-aminobutyric acid receptor subunit alpha-6; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. (465 aa)
GABRA1Gamma-aminobutyric acid receptor subunit alpha-1; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) s [...] (455 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (919 aa)
UNC13BUnc-13 homolog B. (1574 aa)
KCNN2CaMBD domain-containing protein. (776 aa)
CHRNA3Neuronal acetylcholine receptor subunit alpha-3; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (496 aa)
HOMER3-2WH1 domain-containing protein. (353 aa)
KCNS1Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (469 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (670 aa)
KCNJ16Potassium voltage-gated channel subfamily J member 16. (429 aa)
KCNJ12ATP-sensitive inward rectifier potassium channel 12; Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. The inward rectification is probably due to the blockage of outward current by cytoplasmic polyamines and/or magnesium ions. (429 aa)
LOC107057078Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (519 aa)
SLC6A11Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
GNG13G protein gamma domain-containing protein. (67 aa)
CAMK2AProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (489 aa)
CHRNA4Neuronal acetylcholine receptor subunit alpha-4; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub- subfamily. (622 aa)
HOMER2Homer scaffold protein 2. (356 aa)
ABCC8ATP binding cassette subfamily C member 8. (1595 aa)
KCNC1Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (552 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (400 aa)
RPS6KA6Ribosomal protein S6 kinase. (746 aa)
SLITRK4SLIT and NTRK like family member 4. (870 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1458 aa)
KCNG1Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family. (511 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (415 aa)
GNAT3Uncharacterized protein. (354 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositide- containing lipids (By similarity). (489 aa)
CREB1cAMP response element-binding protein. (327 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (647 aa)
IL1RAPL2Interleukin 1 receptor accessory protein like 2. (494 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa)
KCND2BTB domain-containing protein; Belongs to the potassium channel family. (632 aa)
SLITRK2SLIT and NTRK like family member 2. (857 aa)
KCNK18Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (385 aa)
SLC18A2Solute carrier family 18 member A2. (633 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (411 aa)
SLC38A1Aa_trans domain-containing protein. (490 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
KCNG3Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (435 aa)
KCNMB4Uncharacterized protein. (211 aa)
LRFN2Leucine rich repeat and fibronectin type III domain containing 2. (763 aa)
KCNK16Potassium channel subfamily K member. (307 aa)
KCNK17Potassium channel subfamily K member. (380 aa)
KCNV2Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (519 aa)
SLC1A1Amino acid transporter. (527 aa)
KCNK10Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (537 aa)
LIN7ALin-7 homolog A, crumbs cell polarity complex component. (306 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
KCNH8Potassium voltage-gated channel subfamily H member 8. (1108 aa)
SLC22A2MFS domain-containing protein. (589 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1504 aa)
KCNH5Potassium voltage-gated channel subfamily H member 5. (989 aa)
KCNJ4Potassium voltage-gated channel subfamily J member 4. (455 aa)
GRM1Glutamate metabotropic receptor 1. (1152 aa)
SLC6A12Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (607 aa)
SLC6A13Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (603 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1101 aa)
GNALUncharacterized protein. (379 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (499 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
CHRNA9Neuronal acetylcholine receptor subunit alpha-9; Ionotropic receptor that may play a role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. (484 aa)
HCN1Hyperpolarization activated cyclic nucleotide gated potassium channel 1. (846 aa)
CPLX1Complexin 1. (134 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (917 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1126 aa)
GJA10Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (531 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (488 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (439 aa)
KCNJ15Potassium voltage-gated channel subfamily J member 15. (403 aa)
MAOAAmine oxidase. (532 aa)
TSPAN7Tetraspanin. (249 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (622 aa)
KCNF1Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (487 aa)
KCNS3Potassium voltage-gated channel modifier subfamily S member 3; Belongs to the potassium channel family. (494 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (363 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1127 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (373 aa)
SLC5A7Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (578 aa)
SLITRK1SLIT and NTRK like family member 1. (692 aa)
GRM5G_PROTEIN_RECEP_F3_4 domain-containing protein. (1242 aa)
KCNJ11Potassium voltage-gated channel subfamily J member 11. (397 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (477 aa)
KCNG4Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (511 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (863 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)
NAAAN-acylethanolamine acid amidase; Belongs to the acid ceramidase family. (358 aa)
GRIA2Uncharacterized protein. (883 aa)
LIN7CProtein lin-7 homolog C; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains (By similarity); Belongs to the lin-7 family. (197 aa)
GRIN1N-methyl-D-aspartate receptor type 1 subunit. (965 aa)
GNB1WD_REPEATS_REGION domain-containing protein. (340 aa)
KCNA2Shaker subfamily potassium channel Kv1.2 alpha subunit; Belongs to the potassium channel family. (499 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C. (1301 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (682 aa)
NLGN3Neuroligin 3 isoform A1A2. (853 aa)
PRKACBUncharacterized protein; Belongs to the protein kinase superfamily. (398 aa)
SYT1Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. May play a role in dendrite formation by melanocytes; Belongs to the synaptotagmin family. (430 aa)
KCNJ8Uncharacterized protein. (421 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
PPFIBP2PPFIA binding protein 2. (997 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (407 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (266 aa)
SLC18A3MFS domain-containing protein. (522 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (423 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (433 aa)
ADCY6-2Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1217 aa)
PPFIA1PTPRF interacting protein alpha 1. (1232 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (936 aa)
KCNH1Uncharacterized protein. (957 aa)
NLGN1Neuroligin 1 isoform A1A2B. (863 aa)
DLG1Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (929 aa)
KCNK13Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (407 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2425 aa)
DLGAP4DLG associated protein 4. (985 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (598 aa)
PICK1Protein interacting with PRKCA 1. (408 aa)
SLC1A7Amino acid transporter. (560 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1117 aa)
GNB5WD_REPEATS_REGION domain-containing protein. (353 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (944 aa)
KCNQ5Potassium voltage-gated channel subfamily Q member 5; Belongs to the potassium channel family. (912 aa)
AP2B1AP complex subunit beta. (951 aa)
GNB3G protein subunit beta 3. (340 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
KCNV1Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (506 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (By similarity). The KT and KD isoforms fail to stimulate transformation, process outgrowth or survival. Isoform KI25 exhibits tyrosine phosphorylation in the absence of ligand and is unable to mediate survival of neuronal cells. Belongs to the [...] (852 aa)
DLGAP1DLG associated protein 1. (975 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA- gated ion channel (By similarity). (476 aa)
LRTOMTUncharacterized protein. (259 aa)
GRIP2Glutamate receptor interacting protein 2. (1104 aa)
LRRC7Leucine rich repeat containing 7. (1504 aa)
RPS6KA1Ribosomal protein S6 kinase 2 alpha; Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of transcription. (760 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1462 aa)
KCNS2Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (477 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (422 aa)
PPFIA2PTPRF interacting protein alpha 2. (1283 aa)
KCNN3Potassium calcium-activated channel subfamily N member 3. (684 aa)
KCNK9Potassium two pore domain channel subfamily K member 9; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (468 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1123 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1211 aa)
CACNB4SH3 domain-containing protein. (480 aa)
CAMK2BProtein kinase domain-containing protein. (1043 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
KCNA4Potassium channel Shaker cKv1.4; Belongs to the potassium channel family. (662 aa)
DLGAP3DLG associated protein 3. (960 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1963 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (548 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (926 aa)
KCNA3BTB domain-containing protein; Belongs to the potassium channel family. (580 aa)
KCNB2Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (913 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GRIA1Uncharacterized protein. (902 aa)
ENSGALP00000052914Uncharacterized protein. (420 aa)
GRIA3Uncharacterized protein. (888 aa)
GRIA4Uncharacterized protein. (943 aa)
GAD1Glutamate decarboxylase 67. (590 aa)
SLITRK3SLIT and NTRK like family member 3. (886 aa)
GABRG2Gamma-aminobutyric acid receptor subunit gamma-2; Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity). Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) s [...] (474 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
KCNQ4Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (667 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1098 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
GLS2ANK_REP_REGION domain-containing protein. (667 aa)
ACTN2Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity). (923 aa)
SLC32A1Solute carrier family 32 member 1. (521 aa)
KCNA6BTB domain-containing protein; Belongs to the potassium channel family. (613 aa)
GAD2Glutamate decarboxylase 2. (807 aa)
SLC1A2Amino acid transporter. (554 aa)
DLGAP2DLG associated protein 2. (1031 aa)
HOMER1Homer scaffold protein 1. (358 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
KCNK3Potassium channel subfamily K member. (384 aa)
KCNG2Potassium voltage-gated channel subfamily G member 2; Potassium channel subunit. Modulates channel activity (By similarity); Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.2/KCNG2 sub-subfamily. (518 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1936 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
HCN3Cyclic nucleotide-binding domain-containing protein. (821 aa)
GABRQGamma-aminobutyric acid receptor subunit beta-4; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB4 sub- subfamily. (488 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (614 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (88 aa)
KCNAB1Voltage-gated potassium channel subunit beta-1; Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (By similarity). Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity). Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity). Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members (B [...] (401 aa)
SLITRK6SLIT and NTRK like family member 6. (840 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (373 aa)
GNAI3G protein alpha subunit. (354 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...] (1247 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (631 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (1300 aa)
GNB4G protein subunit beta 4. (340 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (564 aa)
KCNC3Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (641 aa)
EPB41L1Erythrocyte membrane protein band 4.1 like 1. (1828 aa)
SH3GLB2Endophilin-B2; Belongs to the endophilin family. (408 aa)
AP2S1Adaptor related protein complex 2 subunit sigma 1. (279 aa)
EPB41L3Erythrocyte membrane protein band 4.1 like 3. (1367 aa)
NLGN2Neuroligin 2. (599 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (423 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1076 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (824 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
KCNMB1Putative calcium-activated potassium channel regulatory subunit. (200 aa)
GRIP1Glutamate receptor interacting protein 1. (1169 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (479 aa)
BCHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (603 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (885 aa)
ABCC9ATP binding cassette subfamily C member 9. (1558 aa)
NLGN4YNeuroligin 4 isoform A2. (836 aa)
LOC415787Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (461 aa)
PPFIBP1Uncharacterized protein. (1039 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (262 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1234 aa)
ENSGALP00000070753ANF_receptor domain-containing protein. (1472 aa)
KCNH4Potassium voltage-gated channel subfamily H member 4. (1052 aa)
TSPOAP1Uncharacterized protein. (2150 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (863 aa)
LRFN1Leucine rich repeat and fibronectin type III domain containing 1. (631 aa)
KCNQ2Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (961 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1132 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (876 aa)
KCNN1Potassium calcium-activated channel subfamily N member 1. (592 aa)
IL1RAPInterleukin 1 receptor accessory protein. (795 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (766 aa)
SLC1A3Amino acid transporter. (543 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (869 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (390 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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