32 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYP2W1-2	Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
	CYP3A4	Uncharacterized protein; Belongs to the cytochrome P450 family. (540 aa)
	CYP3A5	Uncharacterized protein. (508 aa)
	CYP2R1	Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (646 aa)
	CYP4B7	Uncharacterized protein; Belongs to the cytochrome P450 family. (504 aa)
	CYP4A22	Uncharacterized protein. (507 aa)
	CYP46A1	Uncharacterized protein; Belongs to the cytochrome P450 family. (499 aa)
	NR1H4	Farnesoid X receptor. (473 aa)
	CYP2D6	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. (502 aa)
	CYP4V2	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
	CYP2U1	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (524 aa)
	CYP21A1	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (478 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (487 aa)
	RXRA	Retinoid X receptor alpha. (467 aa)
	AHR	Uncharacterized protein. (877 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
	NCOA1	Nuclear receptor coactivator. (1510 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (508 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (723 aa)
	NCOA2	Nuclear receptor coactivator. (1463 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa)
	LOC101749846	Uncharacterized protein; Belongs to the cytochrome P450 family. (668 aa)
	CYP26C1	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (510 aa)
	CYP2J23	Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
	CYP51A1	Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
	CYP39A1	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (466 aa)
	LOC112530469	Uncharacterized protein. (846 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (519 aa)
	TBXAS1	Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (535 aa)
	ARNT	Uncharacterized protein. (936 aa)
	AHRR	Aryl hydrocarbon receptor repressor. (756 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	AHRR	ENSGALP00000047347	ENSGALP00000073536	Uncharacterized protein.	Aryl hydrocarbon receptor repressor.	0.540
AHR	ARNT	ENSGALP00000047347	ENSGALP00000071342	Uncharacterized protein.	Uncharacterized protein.	0.916
AHR	ARNT2	ENSGALP00000047347	ENSGALP00000052707	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.916
AHR	CYP1B1	ENSGALP00000047347	ENSGALP00000048510	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.636
AHRR	AHR	ENSGALP00000073536	ENSGALP00000047347	Aryl hydrocarbon receptor repressor.	Uncharacterized protein.	0.540
AHRR	ARNT	ENSGALP00000073536	ENSGALP00000071342	Aryl hydrocarbon receptor repressor.	Uncharacterized protein.	0.869
AHRR	ARNT2	ENSGALP00000073536	ENSGALP00000052707	Aryl hydrocarbon receptor repressor.	Aryl hydrocarbon receptor nuclear translocator 2.	0.837
AHRR	CYP1B1	ENSGALP00000073536	ENSGALP00000048510	Aryl hydrocarbon receptor repressor.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.680
AHRR	NCOA2	ENSGALP00000073536	ENSGALP00000053171	Aryl hydrocarbon receptor repressor.	Nuclear receptor coactivator.	0.458
ARNT	AHR	ENSGALP00000071342	ENSGALP00000047347	Uncharacterized protein.	Uncharacterized protein.	0.916
ARNT	AHRR	ENSGALP00000071342	ENSGALP00000073536	Uncharacterized protein.	Aryl hydrocarbon receptor repressor.	0.869
ARNT	ARNT2	ENSGALP00000071342	ENSGALP00000052707	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.730
ARNT	CYP1B1	ENSGALP00000071342	ENSGALP00000048510	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.729
ARNT2	AHR	ENSGALP00000052707	ENSGALP00000047347	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.916
ARNT2	AHRR	ENSGALP00000052707	ENSGALP00000073536	Aryl hydrocarbon receptor nuclear translocator 2.	Aryl hydrocarbon receptor repressor.	0.837
ARNT2	ARNT	ENSGALP00000052707	ENSGALP00000071342	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.730
CYP11A1	CYP1B1	ENSGALP00000050999	ENSGALP00000048510	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.412
CYP11A1	CYP21A1	ENSGALP00000050999	ENSGALP00000044393	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family.	0.957
CYP11A1	CYP26B1	ENSGALP00000050999	ENSGALP00000025896	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family.	0.529
CYP11A1	CYP46A1	ENSGALP00000050999	ENSGALP00000018174	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.402