58 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYB5B	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (144 aa)
	ACSS2	Acyl-CoA synthetase short chain family member 2. (696 aa)
	PAOX	Amino_oxidase domain-containing protein. (499 aa)
	CYP2W1-2	Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
	CYP3A4	Uncharacterized protein; Belongs to the cytochrome P450 family. (540 aa)
	CYP3A5	Uncharacterized protein. (508 aa)
	LOC107057078	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (519 aa)
	ALDH3A2	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (490 aa)
	CYP2R1	Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (646 aa)
	ACSS1	Acetyl-coenzyme A synthetase. (665 aa)
	MARC1	MOSC domain-containing protein. (335 aa)
	EPHX1L	EHN domain-containing protein. (486 aa)
	AADAC	Arylacetamide deacetylase. (403 aa)
	CYP4B7	Uncharacterized protein; Belongs to the cytochrome P450 family. (504 aa)
	CYP4A22	Uncharacterized protein. (507 aa)
	CYP46A1	Uncharacterized protein; Belongs to the cytochrome P450 family. (499 aa)
	NR1H4	Farnesoid X receptor. (473 aa)
	CYP2D6	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. (502 aa)
	ADH4	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
	CMBL	DLH domain-containing protein. (245 aa)
	CYP4V2	Uncharacterized protein; Belongs to the cytochrome P450 family. (530 aa)
	SMOX	Spermine oxidase. (535 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
	MAOA	Amine oxidase. (532 aa)
	CYP2U1	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (524 aa)
	NQO2	N-ribosyldihydronicotinamide:quinone reductase 2. (230 aa)
	CYP21A1	Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (478 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (487 aa)
	RXRA	Retinoid X receptor alpha. (467 aa)
	AHR	Uncharacterized protein. (877 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
	NCOA1	Nuclear receptor coactivator. (1510 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (508 aa)
	AOC1	Amine oxidase. (841 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (723 aa)
	FMO3	Dimethylaniline monooxygenase [N-oxide-forming]. (530 aa)
	NCOA2	Nuclear receptor coactivator. (1463 aa)
	PTGS1	Prostaglandin-endoperoxide synthase 1. (607 aa)
	LOC769704	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (557 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa)
	AIP	Aryl-hydrocarbon receptor-interacting protein. (327 aa)
	LOC101749846	Uncharacterized protein; Belongs to the cytochrome P450 family. (668 aa)
	AOC3	Amine oxidase. (761 aa)
	CYP26C1	Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (510 aa)
	BPHL	Biphenyl hydrolase like. (285 aa)
	AOC3-2	Amine oxidase. (762 aa)
	CYP2J23	Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
	CYP51A1	Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
	CYB5R1	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (370 aa)
	CBR3	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (276 aa)
	CYP39A1	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (466 aa)
	LOC112530469	Uncharacterized protein. (846 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (519 aa)
	LOC100857280	PKS_ER domain-containing protein. (404 aa)
	TBXAS1	Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (535 aa)
	LOC415787	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (461 aa)
	ARNT	Uncharacterized protein. (936 aa)
	AHRR	Aryl hydrocarbon receptor repressor. (756 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAC	ACSS2	ENSGALP00000016865	ENSGALP00000005308	Arylacetamide deacetylase.	Acyl-CoA synthetase short chain family member 2.	0.400
AADAC	CYP4V2	ENSGALP00000016865	ENSGALP00000022001	Arylacetamide deacetylase.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.667
ACSS1	ACSS2	ENSGALP00000014052	ENSGALP00000005308	Acetyl-coenzyme A synthetase.	Acyl-CoA synthetase short chain family member 2.	0.908
ACSS1	ALDH3A2	ENSGALP00000014052	ENSGALP00000007586	Acetyl-coenzyme A synthetase.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.961
ACSS1	LOC107057078	ENSGALP00000014052	ENSGALP00000007511	Acetyl-coenzyme A synthetase.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.443
ACSS2	AADAC	ENSGALP00000005308	ENSGALP00000016865	Acyl-CoA synthetase short chain family member 2.	Arylacetamide deacetylase.	0.400
ACSS2	ACSS1	ENSGALP00000005308	ENSGALP00000014052	Acyl-CoA synthetase short chain family member 2.	Acetyl-coenzyme A synthetase.	0.908
ACSS2	ALDH3A2	ENSGALP00000005308	ENSGALP00000007586	Acyl-CoA synthetase short chain family member 2.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.943
ACSS2	CYP4V2	ENSGALP00000005308	ENSGALP00000022001	Acyl-CoA synthetase short chain family member 2.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.426
ACSS2	LOC107057078	ENSGALP00000005308	ENSGALP00000007511	Acyl-CoA synthetase short chain family member 2.	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	0.443
ADH4	ALDH3A2	ENSGALP00000019967	ENSGALP00000007586	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.966
ADH4	CYP4V2	ENSGALP00000019967	ENSGALP00000022001	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.407
ADH4	LOC100857280	ENSGALP00000019967	ENSGALP00000068935	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	PKS_ER domain-containing protein.	0.508
ADH4	MAOA	ENSGALP00000019967	ENSGALP00000026110	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Amine oxidase.	0.914
AHR	AHRR	ENSGALP00000047347	ENSGALP00000073536	Uncharacterized protein.	Aryl hydrocarbon receptor repressor.	0.540
AHR	AIP	ENSGALP00000047347	ENSGALP00000055298	Uncharacterized protein.	Aryl-hydrocarbon receptor-interacting protein.	0.901
AHR	ARNT	ENSGALP00000047347	ENSGALP00000071342	Uncharacterized protein.	Uncharacterized protein.	0.916
AHR	ARNT2	ENSGALP00000047347	ENSGALP00000052707	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.916
AHR	CYP1B1	ENSGALP00000047347	ENSGALP00000048510	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.636
AHRR	AHR	ENSGALP00000073536	ENSGALP00000047347	Aryl hydrocarbon receptor repressor.	Uncharacterized protein.	0.540