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| | TAT | Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (455 aa) |
| | ACAD8 | Uncharacterized protein. (472 aa) |
| | AANAT | Serotonin N-acetyltransferase; Catalyzes the N-acetylation of serotonin into N- acetylserotonin; Belongs to the acetyltransferase family. AANAT subfamily. (205 aa) |
| | CDO1 | Cysteine dioxygenase. (204 aa) |
| | MAT1A | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (396 aa) |
| | MCCC2 | Methylcrotonoyl-CoA carboxylase 2. (560 aa) |
| | TSHB-2 | Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism. (134 aa) |
| | CPS1 | Uncharacterized protein. (1446 aa) |
| | SRM | Spermidine synthase; Belongs to the spermidine/spermine synthase family. (394 aa) |
| | HYKK | APH domain-containing protein. (377 aa) |
| | SRR | Serine racemase. (235 aa) |
| | SLC45A2 | Uncharacterized protein. (543 aa) |
| | ALDH9A1 | Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (579 aa) |
| | PAOX | Amino_oxidase domain-containing protein. (499 aa) |
| | AZIN2 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (520 aa) |
| | DHTKD1 | Dehydrogenase E1 and transketolase domain containing 1. (875 aa) |
| | SERINC3 | Uncharacterized protein. (472 aa) |
| | HPD | 4-hydroxyphenylpyruvate dioxygenase. (393 aa) |
| | DMGDH | Dimethylglycine dehydrogenase. (868 aa) |
| | BHMT2 | Hcy-binding domain-containing protein; Involved in the regulation of homocysteine metabolism. (405 aa) |
| | CCBL1 | Aminotran_1_2 domain-containing protein. (426 aa) |
| | ASPA | Aspartoacylase. (361 aa) |
| | CHDH | Choline dehydrogenase. (716 aa) |
| | GRHPR | Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (326 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (150 aa) |
| | HOGA1 | 4-hydroxy-2-oxoglutarate aldolase 1; Belongs to the DapA family. (326 aa) |
| | UROC1 | Urocanate hydratase 1. (555 aa) |
| | FAH | Fumarylacetoacetase. (419 aa) |
| | KMO | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (486 aa) |
| | PRODH | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (602 aa) |
| | DLAT | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (632 aa) |
| | MTAP | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (280 aa) |
| | ALDH7A1 | Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (536 aa) |
| | HAO1 | FMN hydroxy acid dehydrogenase domain-containing protein. (369 aa) |
| | ARG2 | Arginase. (356 aa) |
| | AADAT | Aminoadipate aminotransferase. (428 aa) |
| | HAAO | 3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa) |
| | ALDH6A1 | Aldehyde dehydrogenase 6 family member A1. (506 aa) |
| | GSTZ1 | Uncharacterized protein; Belongs to the GST superfamily. (266 aa) |
| | MTR | Uncharacterized protein. (1362 aa) |
| | CTH | Cystathionine gamma-lyase. (399 aa) |
| | AMDHD1 | Amidohydrolase domain containing 1. (435 aa) |
| | GADL1 | Glutamate decarboxylase like 1. (511 aa) |
| | IYD | Iodotyrosine deiodinase. (277 aa) |
| | KYNU | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (530 aa) |
| | PAH | Phenylalanine hydroxylase. (446 aa) |
| | DDC | Dopa decarboxylase. (485 aa) |
| | PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (429 aa) |
| | SERINC1 | Uncharacterized protein. (461 aa) |
| | HGD | Homogentisate 1,2-dioxygenase. (439 aa) |
| | DDO | D-aspartate oxidase. (342 aa) |
| | PSAT1 | Phosphoserine aminotransferase. (370 aa) |
| | SLC44A1 | Solute carrier family 44 member 1; Belongs to the CTL (choline transporter-like) family. (666 aa) |
| | SMOX | Spermine oxidase. (535 aa) |
| | TPO | Thyroid peroxidase. (863 aa) |
| | OCA2 | OCA2 melanosomal transmembrane protein. (726 aa) |
| | LIPT1 | BPL/LPL catalytic domain-containing protein. (373 aa) |
| | SLC25A15 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa) |
| | ACAT1 | Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa) |
| | SLC36A4 | Solute carrier family 36 member 4. (466 aa) |
| | NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2. (740 aa) |
| | CARNMT1 | Carnosine N-methyltransferase; N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His). (449 aa) |
| | MCCC1 | Uncharacterized protein. (758 aa) |
| | AGXT | Alanine--glyoxylate and serine--pyruvate aminotransferase. (473 aa) |
| | SERINC2 | Uncharacterized protein. (514 aa) |
| | SMS | PABS domain-containing protein. (367 aa) |
| | SAT1 | Diamine acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)- acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells (By similarity); Belongs to the acetyltransferase family. (171 aa) |
| | TPH2 | Neuronal tryptophan hydroxylase. (489 aa) |
| | HDC | Uncharacterized protein. (664 aa) |
| | IDO2 | Uncharacterized protein. (383 aa) |
| | PIPOX | Pipecolic acid and sarcosine oxidase. (504 aa) |
| | ADI1 | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (180 aa) |
| | SCLY | Aminotran_5 domain-containing protein. (423 aa) |
| | PSPH | Uncharacterized protein. (226 aa) |
| | BCKDHA | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (448 aa) |
| | PYCR3 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (271 aa) |
| | AHCY | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. (444 aa) |
| | PYCR1 | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. (372 aa) |
| | TDO2 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (478 aa) |
| | PDHB | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa) |
| | CKB | Creatine kinase B-type; Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa; Belongs to the ATP:guanido phosphotransferase family. (376 aa) |
| | DLD | Dihydrolipoyl dehydrogenase. (508 aa) |
| | SHMT1 | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa) |
| | DBH | Dopamine beta-hydroxylase. (584 aa) |
| | IVD | Uncharacterized protein. (422 aa) |
| | ACADSB | Uncharacterized protein. (433 aa) |
| | GCSH | Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family. (164 aa) |
| | BCKDHB | Transket_pyr domain-containing protein. (390 aa) |
| | SERINC4 | Serine incorporator 4. (493 aa) |
| | TH | Tyrosine hydroxylase. (491 aa) |
| | PDHA2 | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (404 aa) |
| | HIBADH | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (335 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (418 aa) |
| | AZIN1 | Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (450 aa) |
| | DUOX2 | Dual oxidase 2. (1533 aa) |
| | OAT | Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa) |
| | ALDH18A1 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. (802 aa) |
| | MRI1 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (347 aa) |
| | GPT2 | Glutamic--pyruvic transaminase 2. (544 aa) |
| | ENOPH1 | Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (437 aa) |
| | GLS2 | ANK_REP_REGION domain-containing protein. (667 aa) |
| | SLC25A12 | Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (675 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (693 aa) |
| | AASS | Aminoadipate-semialdehyde synthase. (928 aa) |
| | DLST | Lipoyl-binding domain-containing protein. (474 aa) |
| | OAZ1 | Ornithine decarboxylase antizyme 1; Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin- independent proteolytic destruction by the 26S proteasome. (216 aa) |
| | SLC25A13 | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (682 aa) |
| | OAZ2 | Uncharacterized protein. (178 aa) |
| | SARDH | Sarcosine dehydrogenase. (463 aa) |
| | PDHX | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (502 aa) |
| | QDPR | Uncharacterized protein. (238 aa) |
| | DBT | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa) |
| | TXN2 | Thioredoxin domain-containing protein. (150 aa) |
| | ALDH4A1 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (551 aa) |
| | TXNRD1 | Uncharacterized protein. (530 aa) |
| | DAO | D-amino acid oxidase. (348 aa) |
| | AMD1 | S-adenosylmethionine decarboxylase proenzyme. (341 aa) |
| | ASL2 | Argininosuccinate lyase; Delta crystallin, the principal crystallin in embryonic lens, is found only in birds and reptiles. This protein may also function as an enzymatically active argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. (572 aa) |
| | FOLH1 | Folate hydrolase 1. (751 aa) |
| | BBOX1 | Gamma-butyrobetaine hydroxylase 1. (431 aa) |
| | ASPG | Asparaginase. (602 aa) |
| | MPST | Uncharacterized protein. (297 aa) |
| | SLC25A21 | Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa) |
| | CRYM | Crystallin mu. (252 aa) |
| | LIPT2 | Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family. (230 aa) |
| | RIMKLB | Ribosomal modification protein rimK like family member B. (386 aa) |
| | BCAT1 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (397 aa) |
| | GCDH | Glutaryl-CoA dehydrogenase. (476 aa) |
| | ASRGL1 | Asparaginase and isoaspartyl peptidase 1. (316 aa) |
| | PPM1K | Protein phosphatase, Mg2+/Mn2+ dependent 1K. (372 aa) |
| | AUH | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (350 aa) |
| | PNMT | Phenylethanolamine N-methyltransferase. (265 aa) |
| | SDSL | Uncharacterized protein. (514 aa) |
| | ENSGALP00000069840 | Phosphagen kinase C-terminal domain-containing protein; Belongs to the ATP:guanido phosphotransferase family. (843 aa) |
| | OGDH | Transket_pyr domain-containing protein. (1506 aa) |
| | NAT8L | N-acetyltransferase 8 like. (176 aa) |
| | AGXT2 | Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (471 aa) |
| | SLC25A10 | Solute carrier family 25 member 10; Belongs to the mitochondrial carrier (TC 2.A.29) family. (528 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | CGA | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa) |
| | HAL | Histidine ammonia-lyase; Belongs to the PAL/histidase family. (660 aa) |
| | SERINC5 | Serine incorporator 5. (462 aa) |
| | TMLHE | Trimethyllysine dioxygenase, mitochondrial; Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML). (418 aa) |
| | CBSL | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (577 aa) |
| | GAMT | RMT2 domain-containing protein. (876 aa) |
| | SLC5A5 | Solute carrier family 5 member 5. (805 aa) |
| | RIDA | Reactive intermediate imine deaminase A homolog. (286 aa) |
