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| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa) |
| | SRSF3 | RRM domain-containing protein. (164 aa) |
| | POLR2C | RPOLD domain-containing protein. (275 aa) |
| | POLR2D | RPOL4c domain-containing protein. (142 aa) |
| | NCBP1 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U sn [...] (793 aa) |
| | SF3B3 | Splicing factor 3b subunit 3. (1217 aa) |
| | POLR2E | RNA polymerase II subunit E. (210 aa) |
| | NUP35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (325 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | NUP155 | Nucleoporin 155. (1388 aa) |
| | SRSF10 | RRM domain-containing protein. (262 aa) |
| | CPSF4 | Uncharacterized protein. (243 aa) |
| | GLE1 | GLE1 RNA export mediator. (726 aa) |
| | NUP62 | Nucleoporin 62. (574 aa) |
| | NUP210 | Nucleoporin 210. (1937 aa) |
| | RNPC3 | RNA binding region (RNP1, RRM) containing 3. (550 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (941 aa) |
| | TRA2B | Transformer-2 beta. (289 aa) |
| | SNRPD3 | Small nuclear ribonucleoprotein Sm D3. (126 aa) |
| | NCBP2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (159 aa) |
| | ALYREF | RRM domain-containing protein. (255 aa) |
| | CLP1 | Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phospho [...] (425 aa) |
| | CSTF1 | Cleavage stimulation factor subunit 1. (537 aa) |
| | NUP85 | Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (843 aa) |
| | SF3B1 | Splicing factor 3b subunit 1. (1301 aa) |
| | ZMAT5 | C3H1-type domain-containing protein. (170 aa) |
| | NXT2 | NTF2-related export protein 2; Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export (By similarity). (141 aa) |
| | RNPS1 | RNA binding protein with serine rich domain 1. (284 aa) |
| | SRSF5 | Uncharacterized protein. (264 aa) |
| | ZCRB1 | Uncharacterized protein. (216 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (818 aa) |
| | CPSF2 | Cleavage and polyadenylation specificity factor subunit 2. (782 aa) |
| | NUP133 | Nucleoporin 133. (1181 aa) |
| | SRSF11 | RRM domain-containing protein. (541 aa) |
| | NUP54 | Nucleoporin 54. (557 aa) |
| | CSTF3 | Suf domain-containing protein. (718 aa) |
| | POLDIP3 | RRM domain-containing protein. (418 aa) |
| | METTL14 | N6-adenosine-methyltransferase non-catalytic subunit; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. (459 aa) |
| | POLR2F | RNA polymerase common subunit RPB6. (127 aa) |
| | NUP43 | Nucleoporin 43. (374 aa) |
| | HNRNPK | Heterogeneous nuclear ribonucleoprotein K. (427 aa) |
| | NUP37 | WD_REPEATS_REGION domain-containing protein. (326 aa) |
| | SF3B4 | Splicing factor 3b subunit 4. (418 aa) |
| | FIP1L1 | Fip1 domain-containing protein. (545 aa) |
| | NUP50 | RanBD1 domain-containing protein. (468 aa) |
| | CDC40 | WD_REPEATS_REGION domain-containing protein. (580 aa) |
| | SLBP | Histone stem-loop binding protein. (274 aa) |
| | CPSF3 | Cleavage and polyadenylation specific factor 3. (691 aa) |
| | ZRSR2 | Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (333 aa) |
| | GTF2F2 | General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (262 aa) |
| | NUP58 | Uncharacterized protein. (601 aa) |
| | PCF11 | PCF11 cleavage and polyadenylation factor subunit. (1690 aa) |
| | PDCD7 | Programmed cell death 7. (434 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | DHX38 | Uncharacterized protein. (1230 aa) |
| | EIF4A3 | Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the [...] (412 aa) |
| | POLR2L | Uncharacterized protein. (67 aa) |
| | UPF3B | Smg4_UPF3 domain-containing protein. (478 aa) |
| | NWD1 | WD_REPEATS_REGION domain-containing protein. (425 aa) |
| | SNRNP25 | Small nuclear ribonucleoprotein U11/U12 subunit 25. (129 aa) |
| | POLR2J | RNA polymerase II subunit J. (117 aa) |
| | SNRNP48 | Small nuclear ribonucleoprotein U11/U12 subunit 48. (306 aa) |
| | SARNP | SAP domain-containing protein. (210 aa) |
| | HNRNPH2 | Heterogeneous nuclear ribonucleoprotein H1-like protein. (519 aa) |
| | RAE1 | WD_REPEATS_REGION domain-containing protein. (460 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (419 aa) |
| | SNRPN | Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa) |
| | SRSF5A | Uncharacterized protein. (278 aa) |
| | HNRNPA1 | Uncharacterized protein. (373 aa) |
| | PAPOLB | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (737 aa) |
| | POLR2K | RNA polymerase II subunit K. (134 aa) |
| | SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) |
| | NXF1 | Uncharacterized protein. (615 aa) |
| | HNRNPR | Uncharacterized protein. (661 aa) |
| | NDC1 | NDC1 transmembrane nucleoporin. (779 aa) |
| | NUP98 | Nucleoporin 98. (1772 aa) |
| | PCBP2 | Poly(rC) binding protein 2. (366 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa) |
| | NUP205 | Nucleoporin 205. (2043 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa) |
| | NUP214 | Nucleoporin 214. (1985 aa) |
| | CASC3 | CASC3 exon junction complex subunit. (657 aa) |
| | TPR | Translocated promoter region, nuclear basket protein. (2472 aa) |
| | CPSF7 | Cleavage and polyadenylation specific factor 7. (533 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (163 aa) |
| | THOC2 | THO complex 2. (1505 aa) |
| | NUP88 | Nucleoporin 88. (694 aa) |
| | DDX23 | DEAD-box helicase 23. (816 aa) |
| | SRSF2 | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. (221 aa) |
| | HNRNPA2B1 | Uncharacterized protein. (374 aa) |
| | SRSF7L | Uncharacterized protein. (250 aa) |
| | HNRNPA3 | Heterogeneous nuclear ribonucleoprotein A3. (386 aa) |
| | NUP153 | Nucleoporin 153. (1455 aa) |
| | NUP188 | Uncharacterized protein. (2005 aa) |
| | THOC3 | WD_REPEATS_REGION domain-containing protein. (381 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (548 aa) |
| | FYTTD1 | UAP56-interacting factor; Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore (By similarity). (307 aa) |
| | THOC1 | Death domain-containing protein. (671 aa) |
| | SEC13 | WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (579 aa) |
| | THOC7 | Uncharacterized protein. (323 aa) |
| | AAAS | Aladin WD repeat nucleoporin. (797 aa) |
| | SNRPF | Sm domain-containing protein. (86 aa) |
| | WTAP | WT1 associated protein. (396 aa) |
| | EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). (1222 aa) |
| | TXNL4A | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | PTBP1 | Uncharacterized protein. (556 aa) |
| | LOC776067-2 | Uncharacterized protein. (1667 aa) |
| | LOC101749377 | Uncharacterized protein. (519 aa) |
| | EIF4E | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (221 aa) |
| | POLR2H | Uncharacterized protein. (172 aa) |
| | SNRPGP15 | Small nuclear ribonucleoprotein G. (76 aa) |
| | SNRNP35 | RRM domain-containing protein. (263 aa) |
| | FUS | RRM domain-containing protein. (571 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2. (146 aa) |
| | U2AF2 | U2 small nuclear RNA auxiliary factor 2. (699 aa) |
| | HNRNPD | Uncharacterized protein. (324 aa) |
| | NUP107 | Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (917 aa) |
| | CSTF2 | RRM domain-containing protein. (573 aa) |
| | NUDT21 | Nudix hydrolase domain-containing protein. (473 aa) |
| | PABPN1 | RRM domain-containing protein. (474 aa) |
| | POM121C | Uncharacterized protein. (877 aa) |
