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SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa) | ||||
SRSF3 | RRM domain-containing protein. (164 aa) | ||||
NCBP1 | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U sn [...] (793 aa) | ||||
LSM10 | LSM10, U7 small nuclear RNA associated. (123 aa) | ||||
CPSF4 | Uncharacterized protein. (243 aa) | ||||
SNRPD3 | Small nuclear ribonucleoprotein Sm D3. (126 aa) | ||||
NCBP2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (159 aa) | ||||
ALYREF | RRM domain-containing protein. (255 aa) | ||||
CLP1 | Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phospho [...] (425 aa) | ||||
CSTF1 | Cleavage stimulation factor subunit 1. (537 aa) | ||||
RNPS1 | RNA binding protein with serine rich domain 1. (284 aa) | ||||
SRSF5 | Uncharacterized protein. (264 aa) | ||||
CPSF2 | Cleavage and polyadenylation specificity factor subunit 2. (782 aa) | ||||
SRSF11 | RRM domain-containing protein. (541 aa) | ||||
CSTF3 | Suf domain-containing protein. (718 aa) | ||||
POLDIP3 | RRM domain-containing protein. (418 aa) | ||||
FIP1L1 | Fip1 domain-containing protein. (545 aa) | ||||
CDC40 | WD_REPEATS_REGION domain-containing protein. (580 aa) | ||||
SLBP | Histone stem-loop binding protein. (274 aa) | ||||
CPSF3 | Cleavage and polyadenylation specific factor 3. (691 aa) | ||||
PCF11 | PCF11 cleavage and polyadenylation factor subunit. (1690 aa) | ||||
DHX38 | Uncharacterized protein. (1230 aa) | ||||
EIF4A3 | Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the [...] (412 aa) | ||||
UPF3B | Smg4_UPF3 domain-containing protein. (478 aa) | ||||
SARNP | SAP domain-containing protein. (210 aa) | ||||
LSM11 | LSM11, U7 small nuclear RNA associated. (361 aa) | ||||
SNRPN | Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa) | ||||
SRSF5A | Uncharacterized protein. (278 aa) | ||||
PAPOLB | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (737 aa) | ||||
CASC3 | CASC3 exon junction complex subunit. (657 aa) | ||||
CPSF7 | Cleavage and polyadenylation specific factor 7. (533 aa) | ||||
RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (163 aa) | ||||
THOC2 | THO complex 2. (1505 aa) | ||||
SRSF2 | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. (221 aa) | ||||
SRSF7L | Uncharacterized protein. (250 aa) | ||||
THOC3 | WD_REPEATS_REGION domain-containing protein. (381 aa) | ||||
FYTTD1 | UAP56-interacting factor; Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore (By similarity). (307 aa) | ||||
THOC1 | Death domain-containing protein. (671 aa) | ||||
THOC7 | Uncharacterized protein. (323 aa) | ||||
SNRPF | Sm domain-containing protein. (86 aa) | ||||
SNRPGP15 | Small nuclear ribonucleoprotein G. (76 aa) | ||||
U2AF2 | U2 small nuclear RNA auxiliary factor 2. (699 aa) | ||||
CSTF2 | RRM domain-containing protein. (573 aa) | ||||
NUDT21 | Nudix hydrolase domain-containing protein. (473 aa) | ||||
PABPN1 | RRM domain-containing protein. (474 aa) |