Your Input: | |
| | COPS2 | PCI domain-containing protein. (443 aa) |
| | DCAF7 | WD_REPEATS_REGION domain-containing protein. (460 aa) |
| | RBBP5 | WD_REPEATS_REGION domain-containing protein. (539 aa) |
| | FBXW2 | Uncharacterized protein. (454 aa) |
| | COMMD4 | COMM domain-containing protein. (199 aa) |
| | FBXL20 | F-box and leucine rich repeat protein 20. (436 aa) |
| | VCP | Valosin containing protein. (806 aa) |
| | SPSB3 | SplA/ryanodine receptor domain and SOCS box containing 3. (389 aa) |
| | COMMD10 | COMM domain-containing protein. (203 aa) |
| | FBXL16 | Uncharacterized protein. (503 aa) |
| | KCTD7 | BTB/POZ domain-containing protein KCTD7; May be involved in the control of excitability of cortical neurons. (289 aa) |
| | WDR5B | WD_REPEATS_REGION domain-containing protein. (334 aa) |
| | GPS1 | PCI domain-containing protein. (487 aa) |
| | FBXL8 | F-box domain-containing protein. (379 aa) |
| | KLHL11 | Kelch like family member 11. (689 aa) |
| | SKP2 | F-box domain-containing protein. (520 aa) |
| | ASB1 | Ankyrin repeat and SOCS box containing 1. (309 aa) |
| | FBXL18 | F-box domain-containing protein. (711 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (768 aa) |
| | DCAF10 | DDB1 and CUL4 associated factor 10. (390 aa) |
| | WSB1 | SOCS box-containing WD protein SWiP-1. (421 aa) |
| | FBXL15 | F-box and leucine rich repeat protein 15. (299 aa) |
| | BTBD1 | BTB domain-containing protein. (376 aa) |
| | KLHL22 | BTB domain-containing protein. (638 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity). (163 aa) |
| | COMMD7 | COMM domain-containing protein. (201 aa) |
| | KLHL25 | Kelch like family member 25. (589 aa) |
| | NEURL2 | Neuralized E3 ubiquitin protein ligase 2. (265 aa) |
| | KCTD6 | Potassium channel tetramerization domain containing 6. (237 aa) |
| | KBTBD13 | Kelch repeat and BTB domain containing 13. (452 aa) |
| | COPS7B | COP9 signalosome subunit 7B. (400 aa) |
| | COMMD3 | COMM domain containing 3. (192 aa) |
| | FBXO21 | F-box protein 21. (610 aa) |
| | FEM1C | Fem-1 homolog C. (617 aa) |
| | DDB2 | DNA damage-binding protein 2; Required for DNA repair. Binds to DDB1 to form the UV-damaged DNA-binding protein complex (the UV-DDB complex). The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair. Also appears to function as the substrate recognition module for the DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB1- CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1). The DDB1- CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV [...] (507 aa) |
| | ASB13 | Uncharacterized protein. (278 aa) |
| | DCUN1D1 | DCN1-like protein 1; Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. (259 aa) |
| | COMMD5 | COMM domain-containing protein. (226 aa) |
| | COMMD1 | Copper metabolism domain containing 1. (215 aa) |
| | FBXO11 | F-box protein 11. (886 aa) |
| | DCAF4L2 | WD_REPEATS_REGION domain-containing protein. (501 aa) |
| | DCAF5 | DDB1 and CUL4 associated factor 5. (959 aa) |
| | KLHL2 | BTB domain-containing protein. (599 aa) |
| | DTL | Denticleless protein homolog; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. [...] (720 aa) |
| | CAND1 | Cullin associated and neddylation dissociated 1. (1230 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | LRRC41 | Leucine rich repeat containing 41. (791 aa) |
| | ASB5 | Ankyrin repeat and SOCS box containing 5. (329 aa) |
| | ASB2 | Ankyrin repeat and SOCS box containing 2. (645 aa) |
| | COPS4 | PCI domain-containing protein. (411 aa) |
| | RBX1 | RING-type domain-containing protein. (108 aa) |
| | FBXO7 | F-box domain-containing protein. (526 aa) |
| | GAN | Gigaxonin. (590 aa) |
| | COPS7A | PCI domain-containing protein. (275 aa) |
| | FBXL5 | F-box and leucine rich repeat protein 5. (837 aa) |
| | FBXO9 | F-box domain-containing protein. (435 aa) |
| | ASB11 | Ankyrin repeat and SOCS box containing 11. (322 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (767 aa) |
| | LMO7 | LIM domain 7. (1608 aa) |
| | DCUN1D5 | DCN1-like protein. (236 aa) |
| | KLHL42 | Kelch like family member 42. (503 aa) |
| | RNF7 | RING-type domain-containing protein. (114 aa) |
| | UBE2D1 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | UFD1L | Ubiquitin fusion-degradation 1-like protein. (307 aa) |
| | SOCS6 | Suppressor of cytokine signaling 6. (534 aa) |
| | FEM1A | Fem-1 homolog A. (765 aa) |
| | ANKRD9 | Ankyrin repeat domain 9. (292 aa) |
| | COMMD8 | COMM domain-containing protein. (176 aa) |
| | SENP8 | ULP_PROTEASE domain-containing protein. (224 aa) |
| | VHL | Uncharacterized protein. (161 aa) |
| | COPS5 | MPN domain-containing protein. (337 aa) |
| | FBXO15 | F-box protein 15. (473 aa) |
| | FBXO30 | F-box protein 30. (873 aa) |
| | BTBD6 | BTB domain containing 6. (530 aa) |
| | SPSB4 | SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa) |
| | FBXL4 | F-box and leucine rich repeat protein 4. (620 aa) |
| | DCUN1D3 | Defective in cullin neddylation 1 domain containing 3. (303 aa) |
| | FBXW5 | Uncharacterized protein. (588 aa) |
| | FBXW11 | Uncharacterized protein. (531 aa) |
| | ASB9 | Uncharacterized protein. (294 aa) |
| | CUL5 | Cullin 5; Belongs to the cullin family. (662 aa) |
| | ASB8 | Uncharacterized protein. (284 aa) |
| | KLHL41 | Kelch like family member 41. (606 aa) |
| | FBXO32 | Uncharacterized protein. (355 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | COPS8 | PCI domain-containing protein. (230 aa) |
| | KLHL3 | Kelch like family member 3. (593 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (883 aa) |
| | DCAF17 | DDB1 and CUL4 associated factor 17. (544 aa) |
| | COMMD9 | COMM domain containing 9. (199 aa) |
| | RPS27A | Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (156 aa) |
| | CCNF | Cyclin F; Belongs to the cyclin family. (750 aa) |
| | CUL2 | CULLIN_2 domain-containing protein; Belongs to the cullin family. (774 aa) |
| | UBE2D3 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | KLHL5 | Kelch like family member 5. (508 aa) |
| | UBA3 | Ubiquitin like modifier activating enzyme 3. (442 aa) |
| | FBXL7 | F-box and leucine rich repeat protein 7. (491 aa) |
| | LOC101747587 | Polyubiquitin-B; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; L [...] (305 aa) |
| | KLHL21 | Kelch like family member 21. (600 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (252 aa) |
| | UBE2D2 | Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (238 aa) |
| | FBXO22 | FIST_C domain-containing protein. (393 aa) |
| | FBXO2 | F-box protein 2. (247 aa) |
| | TCEB1 | Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa) |
| | FBXO4 | F-box protein 4. (354 aa) |
| | COMMD2 | COMM domain containing 2. (249 aa) |
| | NEDD8 | NEDD8 ubiquitin like modifier. (85 aa) |
| | TULP4 | TUB like protein 4. (1535 aa) |
| | FBXO44 | Uncharacterized protein. (304 aa) |
| | KBTBD8 | Kelch repeat and BTB domain containing 8. (601 aa) |
| | UBE2M | Ubiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa) |
| | EPAS1 | Endothelial PAS domain protein 1. (867 aa) |
| | FBXL21 | F-box domain-containing protein. (437 aa) |
| | NPLOC4 | NPL4 homolog, ubiquitin recognition factor. (609 aa) |
| | FBXL13 | Uncharacterized protein. (439 aa) |
| | UCHL3 | Ubiquitin carboxyl-terminal hydrolase. (230 aa) |
| | COPS3 | COP9 signalosome complex subunit 3; Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes (By similarity). The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of E3 ligase complexes, leading to modify the Ubl ligase activity (By similarity). (423 aa) |
| | RP11-385D13.1 | WD_REPEATS_REGION domain-containing protein. (866 aa) |
| | UBE2F | NEDD8-conjugating enzyme UBE2F; Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5; Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily. (272 aa) |
| | LRR1 | Leucine rich repeat protein 1. (449 aa) |
| | SOCS2 | Uncharacterized protein. (227 aa) |
| | UBXN7 | UBX domain protein 7. (623 aa) |
| | HIF3A | Hypoxia inducible factor 3 subunit alpha. (458 aa) |
| | FBXL3 | F-box and leucine rich repeat protein 3. (433 aa) |
| | SPSB1 | SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa) |
| | FBXO31 | F-box protein 31. (573 aa) |
| | DCUN1D4 | DCN1-like protein. (302 aa) |
| | DCAF6 | WD_REPEATS_REGION domain-containing protein. (486 aa) |
| | KLHL9 | Kelch-like protein 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis (By similarity). (655 aa) |
| | ASB12 | ANK_REP_REGION domain-containing protein. (327 aa) |
| | COMMD6 | COMM domain containing 6. (207 aa) |
| | FBXO40 | F-box protein 40. (707 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (697 aa) |
| | COP1 | COP1 E3 ubiquitin ligase. (723 aa) |
| | ASB6 | Uncharacterized protein. (475 aa) |
| | FBXO41 | F-box protein 41. (795 aa) |
| | WSB2 | WD repeat and SOCS box containing 2. (471 aa) |
| | DCAF8 | Uncharacterized protein. (444 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (399 aa) |
| | ASB7 | ANK_REP_REGION domain-containing protein. (324 aa) |
| | NFE2L2 | BZIP domain-containing protein. (593 aa) |
| | DCUN1D2 | DCN1-like protein. (259 aa) |
