12 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HSD11B1b	Uncharacterized protein. (301 aa)
	UGT1A1	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (532 aa)
	CYP3A4	Uncharacterized protein; Belongs to the cytochrome P450 family. (540 aa)
	CYP3A5	Uncharacterized protein. (508 aa)
	SPIA3	SERPIN domain-containing protein; Belongs to the serpin family. (419 aa)
	SPIA5	SERPIN domain-containing protein; Belongs to the serpin family. (423 aa)
	SPIA4	SERPIN domain-containing protein; Belongs to the serpin family. (425 aa)
	UGT2A1	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
	SPIA1	SERPIN domain-containing protein; Belongs to the serpin family. (425 aa)
	ABCB1-2	Multidrug resistance protein 1. (1288 aa)
	HSD11B2	Hydroxysteroid 11-beta dehydrogenase 2. (349 aa)
	SPIA9	SERPIN domain-containing protein; Belongs to the serpin family. (432 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB1-2	CYP3A4	ENSGALP00000037427	ENSGALP00000007048	Multidrug resistance protein 1.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.657
ABCB1-2	CYP3A5	ENSGALP00000037427	ENSGALP00000007068	Multidrug resistance protein 1.	Uncharacterized protein.	0.611
CYP3A4	ABCB1-2	ENSGALP00000007048	ENSGALP00000037427	Uncharacterized protein; Belongs to the cytochrome P450 family.	Multidrug resistance protein 1.	0.657
CYP3A4	CYP3A5	ENSGALP00000007048	ENSGALP00000007068	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.929
CYP3A4	UGT1A1	ENSGALP00000007048	ENSGALP00000006662	Uncharacterized protein; Belongs to the cytochrome P450 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.965
CYP3A4	UGT2A1	ENSGALP00000007048	ENSGALP00000019241	Uncharacterized protein; Belongs to the cytochrome P450 family.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.975
CYP3A5	ABCB1-2	ENSGALP00000007068	ENSGALP00000037427	Uncharacterized protein.	Multidrug resistance protein 1.	0.611
CYP3A5	CYP3A4	ENSGALP00000007068	ENSGALP00000007048	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.929
CYP3A5	HSD11B1b	ENSGALP00000007068	ENSGALP00000002086	Uncharacterized protein.	Uncharacterized protein.	0.477
CYP3A5	UGT1A1	ENSGALP00000007068	ENSGALP00000006662	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.971
CYP3A5	UGT2A1	ENSGALP00000007068	ENSGALP00000019241	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.982
HSD11B1b	CYP3A5	ENSGALP00000002086	ENSGALP00000007068	Uncharacterized protein.	Uncharacterized protein.	0.477
HSD11B1b	HSD11B2	ENSGALP00000002086	ENSGALP00000042090	Uncharacterized protein.	Hydroxysteroid 11-beta dehydrogenase 2.	0.878
HSD11B1b	UGT1A1	ENSGALP00000002086	ENSGALP00000006662	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.909
HSD11B1b	UGT2A1	ENSGALP00000002086	ENSGALP00000019241	Uncharacterized protein.	UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.	0.925
HSD11B2	HSD11B1b	ENSGALP00000042090	ENSGALP00000002086	Hydroxysteroid 11-beta dehydrogenase 2.	Uncharacterized protein.	0.878
SPIA1	SPIA3	ENSGALP00000036785	ENSGALP00000017841	SERPIN domain-containing protein; Belongs to the serpin family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.634
SPIA1	SPIA4	ENSGALP00000036785	ENSGALP00000017850	SERPIN domain-containing protein; Belongs to the serpin family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.713
SPIA1	SPIA5	ENSGALP00000036785	ENSGALP00000017843	SERPIN domain-containing protein; Belongs to the serpin family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.654
SPIA1	SPIA9	ENSGALP00000036785	ENSGALP00000061495	SERPIN domain-containing protein; Belongs to the serpin family.	SERPIN domain-containing protein; Belongs to the serpin family.	0.418