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| | BUD13 | BUD13 homolog. (770 aa) |
| | DDX41 | Uncharacterized protein. (617 aa) |
| | SNRPN | Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa) |
| | ENSGALP00000046940 | Uncharacterized protein. (164 aa) |
| | DHX8 | DEAH-box helicase 8. (1163 aa) |
| | SRSF5A | Uncharacterized protein. (278 aa) |
| | HNRNPA1 | Uncharacterized protein. (373 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (826 aa) |
| | LUC7L3 | Uncharacterized protein. (469 aa) |
| | SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) |
| | PUF60 | Uncharacterized protein. (364 aa) |
| | SRSF6 | Uncharacterized protein. (351 aa) |
| | GEMIN8 | Gem nuclear organelle associated protein 8. (241 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (943 aa) |
| | LSM3 | Uncharacterized protein. (102 aa) |
| | DDX17 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. (655 aa) |
| | PPIE | Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (321 aa) |
| | DNAJC17 | J domain-containing protein. (311 aa) |
| | YTHDC1 | YTH domain-containing protein. (752 aa) |
| | GPKOW | G-patch domain-containing protein. (244 aa) |
| | CHUK | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. (724 aa) |
| | SRPK1 | SRSF protein kinase 1. (748 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa) |
| | DCPS | Decapping enzyme, scavenger. (230 aa) |
| | RBM14 | RNA binding motif protein 14. (750 aa) |
| | CELF6 | Uncharacterized protein. (465 aa) |
| | SFSWAP | Splicing factor SWAP. (1001 aa) |
| | RSRC1 | Arginine and serine rich coiled-coil 1. (306 aa) |
| | IK | Uncharacterized protein. (553 aa) |
| | CASC3 | CASC3 exon junction complex subunit. (657 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (163 aa) |
| | RBM10 | Uncharacterized protein. (911 aa) |
| | ENSGALP00000055342 | RRM domain-containing protein. (175 aa) |
| | ESRP2 | Epithelial splicing regulatory protein 2; mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity); Belongs to the ESRP family. (728 aa) |
| | PRPF18 | SFM domain-containing protein. (351 aa) |
| | DBR1 | Lariat debranching enzyme; Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis (By similarity); Belongs to the lariat debranching enzyme family. (486 aa) |
| | SRPK2 | SRSF protein kinase 2. (690 aa) |
| | SNRNP200 | Helicase_PWI domain-containing protein. (614 aa) |
| | SRSF2 | Serine/arginine-rich splicing factor 2; Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. (221 aa) |
| | ZMAT2 | U1-type domain-containing protein. (199 aa) |
| | UBL5 | Ubiquitin like 5. (73 aa) |
| | SRSF7L | Uncharacterized protein. (250 aa) |
| | SLU7 | Pre-mRNA-splicing factor SLU7; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. (671 aa) |
| | HNRNPA3 | Heterogeneous nuclear ribonucleoprotein A3. (386 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | LENG8 | Leukocyte receptor cluster member 8. (801 aa) |
| | YJU2 | YJU2 splicing factor homolog. (421 aa) |
| | SRSF7 | Uncharacterized protein. (238 aa) |
| | ENSGALP00000044204 | RRM domain-containing protein. (127 aa) |
| | LUC7L2 | Uncharacterized protein. (398 aa) |
| | SMN | Survival motor neuron protein. (264 aa) |
| | WDR25 | WD repeat domain 25. (523 aa) |
| | CELF5 | CUGBP Elav-like family member 5. (611 aa) |
| | CELF3 | CUGBP Elav-like family member 3. (447 aa) |
| | SNRNP25 | Small nuclear ribonucleoprotein U11/U12 subunit 25. (129 aa) |
| | SNRPB2 | Small nuclear ribonucleoprotein polypeptide B2. (226 aa) |
| | MFAP1 | Microfibrillar-associated protein 1; Involved in pre-mRNA splicing as a component of the spliceosome; Belongs to the MFAP1 family. (439 aa) |
| | NOVA1 | Uncharacterized protein. (507 aa) |
| | CACTIN | Cactin, spliceosome C complex subunit. (731 aa) |
| | PRPF3 | U4/U6 small nuclear ribonucleoprotein Prp3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). (684 aa) |
| | DDX20 | DEAD-box helicase 20; Belongs to the DEAD box helicase family. (767 aa) |
| | GLOD4 | Uncharacterized protein. (1072 aa) |
| | SRSF1 | Serine/arginine-rich splicing factor 1; May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. (248 aa) |
| | EIF4A3 | Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the [...] (412 aa) |
| | DHX38 | Uncharacterized protein. (1230 aa) |
| | PSIP1 | Lens epithelium-derived growth factor; Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis (By similarity); Belongs to the HDGF family. (579 aa) |
| | CWF19L2 | CWF19 like cell cycle control factor 2. (852 aa) |
| | WBP4 | WW domain-binding protein 4; Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex. (398 aa) |
| | C3H2ORF3 | GCFC domain-containing protein. (945 aa) |
| | ZRSR2 | Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (333 aa) |
| | SF3B6 | Splicing factor 3b subunit 6. (91 aa) |
| | U2AF1 | U2snRNP auxiliary factor small subunit. (237 aa) |
| | TXNL4B | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa) |
| | CDC40 | WD_REPEATS_REGION domain-containing protein. (580 aa) |
| | KIAA0907 | KH homology domain-containing protein 4; RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches. (619 aa) |
| | SF3B4 | Splicing factor 3b subunit 4. (418 aa) |
| | STRAP | Serine-threonine kinase receptor-associated protein; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. ST [...] (350 aa) |
| | PRPF4B | Pre-mRNA processing factor 4B. (1105 aa) |
| | PRPF40A | Pre-mRNA processing factor 40 homolog A. (853 aa) |
| | METTL14 | N6-adenosine-methyltransferase non-catalytic subunit; The METTL3-METTL14 heterodimer forms a N6-methyltransferase complex that methylates adenosine residues at the N(6) position of some mRNAs and regulates the circadian clock, differentiation of embryonic stem cells and cortical neurogenesis. In the heterodimer formed with METTL3, METTL14 constitutes the RNA-binding scaffold that recognizes the substrate rather than the catalytic core. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in mRNA stability and processing. (459 aa) |
| | PHF5A | Uncharacterized protein. (110 aa) |
| | SNU13 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | WBP11 | Uncharacterized protein. (648 aa) |
| | TRA2A | RRM domain-containing protein. (277 aa) |
| | PRPF38A | PRP38_assoc domain-containing protein. (312 aa) |
| | SNW1 | SNW domain containing 1. (538 aa) |
| | GEMIN2 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (263 aa) |
| | AQR | Aquarius intron-binding spliceosomal factor. (1513 aa) |
| | ZCRB1 | Uncharacterized protein. (216 aa) |
| | SRSF5 | Uncharacterized protein. (264 aa) |
| | RNPS1 | RNA binding protein with serine rich domain 1. (284 aa) |
| | LSM8 | U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa) |
| | CWC22 | Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. (926 aa) |
| | PRPF4 | Pre-mRNA processing factor 4. (537 aa) |
| | CLNS1A | Chloride nucleotide-sensitive channel 1A. (238 aa) |
| | CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (686 aa) |
| | SF3B1 | Splicing factor 3b subunit 1. (1301 aa) |
| | SF3A1 | Uncharacterized protein. (790 aa) |
| | SNRPA1 | LRRcap domain-containing protein. (255 aa) |
| | NCBP2 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (159 aa) |
| | SNRPD3 | Small nuclear ribonucleoprotein Sm D3. (126 aa) |
| | E1BWT0_CHICK | Protein kinase domain-containing protein. (188 aa) |
| | TRA2B | Transformer-2 beta. (289 aa) |
| | HTATSF1 | HIV-1 Tat specific factor 1. (450 aa) |
| | DDX46 | DEAD-box helicase 46. (1043 aa) |
| | RBM17 | RNA binding motif protein 17. (401 aa) |
| | HNRNPA0 | Heterogeneous nuclear ribonucleoprotein A0. (307 aa) |
| | C5H11orf58 | Small acidic protein; Belongs to the SMAP family. (172 aa) |
| | PRPF6 | Pre-mRNA processing factor 6. (941 aa) |
| | LOC422214 | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (168 aa) |
| | TFIP11 | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. (827 aa) |
| | RNPC3 | RNA binding region (RNP1, RRM) containing 3. (550 aa) |
| | ISY1 | Uncharacterized protein. (280 aa) |
| | RBM41 | RNA binding motif protein 41. (398 aa) |
| | BUD31 | BUD31 homolog. (144 aa) |
| | RBM22 | Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle. Belongs to the SLT11 family. (420 aa) |
| | C9orf78 | Chromosome 9 open reading frame 78. (289 aa) |
| | SRSF10 | RRM domain-containing protein. (262 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1528 aa) |
| | RBM44 | RRM domain-containing protein. (470 aa) |
| | SETX | Senataxin. (2801 aa) |
| | DDX5 | Uncharacterized protein; Belongs to the DEAD box helicase family. (603 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (138 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | TARDBP | TAR DNA-binding protein 43; Probably involved in transcriptional repression (By similarity). May play a role in the maintenance of the circadian clock periodicity (By similarity). (414 aa) |
| | SNRPC | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (160 aa) |
| | SF3B3 | Splicing factor 3b subunit 3. (1217 aa) |
| | CELF4-2 | Uncharacterized protein. (114 aa) |
| | SMU1 | WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family. (513 aa) |
| | SNIP1 | Smad nuclear interacting protein 1. (364 aa) |
| | ENSGALP00000074305 | Uncharacterized protein. (126 aa) |
| | SRSF4 | Serine and arginine rich splicing factor 4. (475 aa) |
| | USP49 | Ubiquitin carboxyl-terminal hydrolase. (715 aa) |
| | LUC7L | LUC7 like. (332 aa) |
| | ENSGALP00000073832 | Uncharacterized protein. (112 aa) |
| | ENSGALP00000073813 | Uncharacterized protein. (107 aa) |
| | PTBP2 | Polypyrimidine tract binding protein 2. (675 aa) |
| | ENSGALP00000073643 | Uncharacterized protein. (124 aa) |
| | ENSGALP00000073639 | Uncharacterized protein. (118 aa) |
| | ENSGALP00000073529 | GCFC domain-containing protein. (175 aa) |
| | SCNM1 | Sodium channel modifier 1. (200 aa) |
| | ENSGALP00000072315 | Uncharacterized protein. (94 aa) |
| | ENSGALP00000072093 | GCFC domain-containing protein. (94 aa) |
| | ENSGALP00000071632 | GCFC domain-containing protein. (128 aa) |
| | PRMT7 | Protein arginine N-methyltransferase 7; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being [...] (689 aa) |
| | ENSGALP00000070935 | Uncharacterized protein. (468 aa) |
| | ENSGALP00000070600 | Protein kinase domain-containing protein. (154 aa) |
| | U2AF2 | U2 small nuclear RNA auxiliary factor 2. (699 aa) |
| | ENSGALP00000070321 | GCFC domain-containing protein. (146 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2. (146 aa) |
| | PRPF39 | Pre-mRNA processing factor 39. (680 aa) |
| | ENSGALP00000070086 | Uncharacterized protein. (597 aa) |
| | ENSGALP00000069837 | Uncharacterized protein. (124 aa) |
| | SNRNP35 | RRM domain-containing protein. (263 aa) |
| | ENSGALP00000069569 | GCFC domain-containing protein. (175 aa) |
| | LOC112530170 | SEC63 domain-containing protein. (235 aa) |
| | ENSGALP00000068982 | Uncharacterized protein. (103 aa) |
| | ENSGALP00000068951 | Uncharacterized protein. (107 aa) |
| | ENSGALP00000068729 | GCFC domain-containing protein. (144 aa) |
| | ENSGALP00000068602 | Uncharacterized protein. (107 aa) |
| | RBMX2 | RRM domain-containing protein. (253 aa) |
| | ENSGALP00000068544 | Uncharacterized protein. (132 aa) |
| | LOC100859276 | RNA binding motif protein 4. (368 aa) |
| | PPIL1 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (298 aa) |
| | ENSGALP00000068167 | GCFC domain-containing protein. (156 aa) |
| | ENSGALP00000068114 | GCFC domain-containing protein. (116 aa) |
| | ENSGALP00000067656 | Uncharacterized protein. (174 aa) |
| | ENSGALP00000067595 | Uncharacterized protein. (538 aa) |
| | ENSGALP00000067396 | Uncharacterized protein. (109 aa) |
| | DNAJC8 | DnaJ heat shock protein family (Hsp40) member C8. (259 aa) |
| | SNRPGP15 | Small nuclear ribonucleoprotein G. (76 aa) |
| | CELF2 | CUGBP Elav-like family member 2; RNA-binding protein implicated in the regulation of several post-transcriptional events. May be involved in mRNA translation repression and stability. Mediates exon inclusion in TNNT2 pre-mRNA. (532 aa) |
| | ENSGALP00000066481 | Uncharacterized protein. (107 aa) |
| | ENSGALP00000066472 | GCFC domain-containing protein. (128 aa) |
| | ENSGALP00000066377 | Helicase C-terminal domain-containing protein. (528 aa) |
| | CCDC130 | Coiled-coil domain containing 130. (337 aa) |
| | CELF1 | CUGBP Elav-like family member 1; RNA-binding protein that may be involved in pre-mRNA alternative splicing, mRNA translation activation and stability. Belongs to the CELF/BRUNOL family. (512 aa) |
| | ENSGALP00000065976 | Cwf21 domain-containing protein. (255 aa) |
| | LOC107052453 | LRRcap domain-containing protein. (320 aa) |
| | CDC5L | Cell division cycle 5 like. (1410 aa) |
| | CELF4 | RRM domain-containing protein. (173 aa) |
| | ENSGALP00000065498 | Uncharacterized protein. (107 aa) |
| | RBM6 | RanBP2-type domain-containing protein. (1181 aa) |
| | ENSGALP00000065158 | GCFC domain-containing protein. (157 aa) |
| | ENSGALP00000064960 | GCFC domain-containing protein. (146 aa) |
| | TXNL4A | Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa) |
| | EFTUD2 | 116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). (1222 aa) |
| | ENSGALP00000063391 | GCFC domain-containing protein. (155 aa) |
| | LSM6 | Sm domain-containing protein. (80 aa) |
| | ENSGALP00000062793 | GCFC domain-containing protein. (135 aa) |
| | SNRPF | Sm domain-containing protein. (86 aa) |
| | CWC15 | Uncharacterized protein. (230 aa) |
| | MTHFSD | Methenyltetrahydrofolate synthetase domain containing. (321 aa) |
| | RBM19 | Uncharacterized protein. (980 aa) |
| | PLRG1 | Pleiotropic regulator 1. (516 aa) |
| | ENSGALP00000059703 | GCFC domain-containing protein. (96 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (548 aa) |
| | PRPF19 | Pre-mRNA-processing factor 19; Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity; Belongs to the WD repeat PRP19 family. (504 aa) |
| | PAXBP1 | PAX3 and PAX7 binding protein 1. (914 aa) |
| | SCAF11 | RING-type domain-containing protein. (1361 aa) |
| | BCAS2 | Uncharacterized protein. (225 aa) |
| | SRRM3 | Serine/arginine repetitive matrix 3. (445 aa) |
| | CWC25 | CWC25 spliceosome associated protein homolog. (416 aa) |
| | SF3A3 | Splicing factor 3a subunit 3. (501 aa) |
| | SYF2 | Uncharacterized protein. (252 aa) |
| | SF3A2 | Splicing factor 3a subunit 2. (315 aa) |
| | RNF113B | Zinc finger protein 183. (328 aa) |
| | SRSF3 | RRM domain-containing protein. (164 aa) |
| | HNRNPM | Uncharacterized protein. (709 aa) |
| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa) |
