107 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LEO1	Uncharacterized protein. (657 aa)
	CDK7	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	TAF4B	TATA-box binding protein associated factor 4b. (832 aa)
	URB1	URB1 ribosome biogenesis homolog. (2274 aa)
	RSAD2	Viperin. (354 aa)
	EXOSC8	Exosome component 8. (283 aa)
	GAR1	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (219 aa)
	PSPC1	Paraspeckle component 1; Together with NONO, required for the formation of nuclear paraspeckles. Acts as a coactivator during transcriptional activation. Binds to RNA. May act as a regulator the circadian clock (By similarity); Belongs to the PSPC family. (523 aa)
	NUFIP1	C2H2-type domain-containing protein. (527 aa)
	OTP	Orthopedia homeobox. (325 aa)
	CHCHD1	Coiled-coil-helix-coiled-coil-helix domain containing 1. (124 aa)
	RERG	RAS like estrogen regulated growth inhibitor. (199 aa)
	TAF1C	TATA-box binding protein associated factor, RNA polymerase I subunit C. (878 aa)
	TOP1	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (747 aa)
	EN2	Homeobox protein engrailed-2. (289 aa)
	HEATR1	BP28CT domain-containing protein. (328 aa)
	NFIC	Nuclear factor 1 C-type; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (549 aa)
	ENSGALP00000046146	Uncharacterized protein. (576 aa)
	MALT1	MALT1 paracaspase. (816 aa)
	DSN1	Dsn1 protein. (349 aa)
	WDR43	WD_REPEATS_REGION domain-containing protein. (661 aa)
	HOXB5	Homeobox protein Hox-B5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (264 aa)
	WDR33	WD_REPEATS_REGION domain-containing protein. (331 aa)
	ORC6	Uncharacterized protein. (402 aa)
	KIT	Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. Activated KIT also transmits signals via [...] (960 aa)
	JAZF1	Uncharacterized protein. (243 aa)
	PAK6	Protein kinase domain-containing protein. (114 aa)
	NUAK1	NUAK family kinase 1. (675 aa)
	ZNRF2	Zinc and ring finger 2. (232 aa)
	DCAF1	DDB1 and CUL4 associated factor 1. (1505 aa)
	MRI1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (347 aa)
	SMAD7	Mothers against decapentaplegic homolog. (388 aa)
	USO1	Uncharacterized protein. (963 aa)
	ENSGALP00000056134	Uncharacterized protein. (348 aa)
	NEDD1	WD_REPEATS_REGION domain-containing protein. (671 aa)
	DEAF1	DEAF1. (546 aa)
	NOLC1	Nucleolar and coiled-body phosphoprotein 1. (696 aa)
	SMAD7B	Mothers against decapentaplegic homolog. (388 aa)
	NOP53	NOP53 ribosome biogenesis factor. (598 aa)
	PCASP2	Uncharacterized protein. (741 aa)
	POLR1B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1117 aa)
	AFF4	AF4/FMR2 family member 4. (1152 aa)
	UTP4	UTP4 small subunit processome component. (912 aa)
	PLRG1	Pleiotropic regulator 1. (516 aa)
	ENSGALP00000060450	Uncharacterized protein. (131 aa)
	POLR1E	RNA polymerase I subunit E. (445 aa)
	POLR1C	RPOLD domain-containing protein. (346 aa)
	NOP56	Nop domain-containing protein. (700 aa)
	ENSGALP00000061835	Uncharacterized protein. (181 aa)
	CAMK4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (366 aa)
	ENSGALP00000064543	Uncharacterized protein. (163 aa)
	RGS22	Uncharacterized protein. (571 aa)
	ENSGALP00000065247	Uncharacterized protein. (165 aa)
	ENSGALP00000065439	Uncharacterized protein. (163 aa)
	ENSGALP00000065576	Uncharacterized protein. (262 aa)
	ENSGALP00000066296	Uncharacterized protein. (471 aa)
	ENSGALP00000066313	Uncharacterized protein. (182 aa)
	ENSGALP00000067205	Uncharacterized protein. (262 aa)
	ENSGALP00000067308	Uncharacterized protein. (221 aa)
	ENSGALP00000067494	Rho-GAP domain-containing protein. (75 aa)
	ENSGALP00000067535	Uncharacterized protein. (273 aa)
	ENSGALP00000067646	Uncharacterized protein. (218 aa)
	ENSGALP00000067965	Uncharacterized protein. (223 aa)
	ENSGALP00000068003	Uncharacterized protein. (126 aa)
	ENSGALP00000068048	Uncharacterized protein. (264 aa)
	ENSGALP00000068076	Uncharacterized protein. (90 aa)
	ENSGALP00000068584	Uncharacterized protein. (262 aa)
	ENSGALP00000069323	annotation not available (90 aa)
	AKNA	Uncharacterized protein. (1246 aa)
	RPP38	Ribosomal_L7Ae domain-containing protein. (332 aa)
	NFKBIE	NFKB inhibitor epsilon. (363 aa)
	ENSGALP00000070306	Protein kinase domain-containing protein. (116 aa)
	ENSGALP00000070424	Uncharacterized protein. (262 aa)
	ENSGALP00000070492	Rho-GAP domain-containing protein. (85 aa)
	ENSGALP00000070564	Uncharacterized protein. (223 aa)
	ENSGALP00000070755	Uncharacterized protein. (223 aa)
	ENSGALP00000070882	Uncharacterized protein. (126 aa)
	ENSGALP00000071074	Uncharacterized protein. (127 aa)
	SMUG1	Single-strand-selective monofunctional uracil-DNA glycosylase 1. (332 aa)
	ENSGALP00000071551	Uncharacterized protein. (270 aa)
	ENSGALP00000071763	Rho-GAP domain-containing protein. (218 aa)
	ENSGALP00000071802	Uncharacterized protein. (157 aa)
	ENSGALP00000072042	Uncharacterized protein. (270 aa)
	PTPN20	Protein tyrosine phosphatase non-receptor type 20. (351 aa)
	CAMK4L	Protein kinase domain-containing protein. (190 aa)
	ENSGALP00000072341	Uncharacterized protein. (223 aa)
	DAB2	DAB adaptor protein 2. (715 aa)
	ENSGALP00000072659	Uncharacterized protein. (223 aa)
	MAP3K14	Protein kinase domain-containing protein. (941 aa)
	ENSGALP00000072811	Rho-GAP domain-containing protein. (169 aa)
	ENSGALP00000072994	Uncharacterized protein. (120 aa)
	ENSGALP00000073375	Uncharacterized protein. (223 aa)
	NRIP1	Nuclear receptor interacting protein 1. (1155 aa)
	ENSGALP00000074195	Uncharacterized protein. (224 aa)
	RPAIN	RPA interacting protein. (218 aa)
	RAI14	Retinoic acid induced 14. (974 aa)
	FBLIM1	Filamin binding LIM protein 1. (338 aa)
	TRAF4	TNF receptor-associated factor. (470 aa)
	CCDC137	Coiled-coil domain containing 137. (322 aa)
	TCOF1	LisH domain-containing protein. (974 aa)
	IP6K2	Kinase; Belongs to the inositol phosphokinase (IPK) family. (424 aa)
	SMARCB1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Involved in chromatin-remodeling. Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity). (386 aa)
	DDX46	DEAD-box helicase 46. (1043 aa)
	MRPL23	Uncharacterized protein. (215 aa)
	FHIT	Bis(5'-adenosyl)-triphosphatase. (148 aa)
	NOP58	NOP58 ribonucleoprotein. (527 aa)
	PTPN13	Protein tyrosine phosphatase non-receptor type 13. (2515 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFF4	LEO1	ENSGALP00000057578	ENSGALP00000052226	AF4/FMR2 family member 4.	Uncharacterized protein.	0.704
AFF4	WDR33	ENSGALP00000057578	ENSGALP00000049419	AF4/FMR2 family member 4.	WD_REPEATS_REGION domain-containing protein.	0.459
CAMK4	CAMK4L	ENSGALP00000063204	ENSGALP00000072270	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.900
CAMK4L	CAMK4	ENSGALP00000072270	ENSGALP00000063204	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.900
CDK7	POLR1B	ENSGALP00000023830	ENSGALP00000057133	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.650
CDK7	POLR1C	ENSGALP00000023830	ENSGALP00000061621	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	RPOLD domain-containing protein.	0.743
CDK7	POLR1E	ENSGALP00000023830	ENSGALP00000061339	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	RNA polymerase I subunit E.	0.519
CDK7	TAF1C	ENSGALP00000023830	ENSGALP00000042211	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	TATA-box binding protein associated factor, RNA polymerase I subunit C.	0.580
CDK7	TAF4B	ENSGALP00000023830	ENSGALP00000024358	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	TATA-box binding protein associated factor 4b.	0.646
CHCHD1	MRPL23	ENSGALP00000041397	ENSGALP00000010578	Coiled-coil-helix-coiled-coil-helix domain containing 1.	Uncharacterized protein.	0.865
DDX46	NOP58	ENSGALP00000010325	ENSGALP00000013761	DEAD-box helicase 46.	NOP58 ribonucleoprotein.	0.523
ENSGALP00000046146	RGS22	ENSGALP00000046146	ENSGALP00000064966	Uncharacterized protein.	Uncharacterized protein.	0.930
ENSGALP00000056134	ENSGALP00000066296	ENSGALP00000056134	ENSGALP00000066296	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSGALP00000056134	WDR33	ENSGALP00000056134	ENSGALP00000049419	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.952
ENSGALP00000060450	ENSGALP00000067205	ENSGALP00000060450	ENSGALP00000067205	Uncharacterized protein.	Uncharacterized protein.	0.418
ENSGALP00000060450	ENSGALP00000067308	ENSGALP00000060450	ENSGALP00000067308	Uncharacterized protein.	Uncharacterized protein.	0.425
ENSGALP00000060450	ENSGALP00000067646	ENSGALP00000060450	ENSGALP00000067646	Uncharacterized protein.	Uncharacterized protein.	0.450
ENSGALP00000060450	ENSGALP00000067965	ENSGALP00000060450	ENSGALP00000067965	Uncharacterized protein.	Uncharacterized protein.	0.453
ENSGALP00000060450	ENSGALP00000068048	ENSGALP00000060450	ENSGALP00000068048	Uncharacterized protein.	Uncharacterized protein.	0.412
ENSGALP00000060450	ENSGALP00000068076	ENSGALP00000060450	ENSGALP00000068076	Uncharacterized protein.	Uncharacterized protein.	0.458