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| | KDM6A | Uncharacterized protein. (1484 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa) |
| | RIPPLY2 | Ripply transcriptional repressor 2. (131 aa) |
| | POGLUT1 | CAP10 domain-containing protein. (392 aa) |
| | ARL13B | ADP ribosylation factor like GTPase 13B. (425 aa) |
| | IFT57 | Intraflagellar transport 57. (532 aa) |
| | PCSK5 | Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1864 aa) |
| | MSX1 | Homeobox protein GHOX-7; Probably plays a role in patterning events during embryonic limb development. May also be involved in programmed cell death. (288 aa) |
| | MIB1 | Mindbomb E3 ubiquitin protein ligase 1. (1167 aa) |
| | TBC1D32 | TBC1 domain family member 32. (1301 aa) |
| | E1C1Y1_CHICK | Uncharacterized protein. (351 aa) |
| | AHI1 | Abelson helper integration site 1. (1242 aa) |
| | CITED2 | Cited2/melanocyte specific gene-related gene 1 MRG1. (236 aa) |
| | EDN1 | Endothelin 1. (194 aa) |
| | CFC1 | Cryptic protein; May play a role in mesoderm and/or neural patterning during gastrulation. (193 aa) |
| | BMP4 | Bone morphogenetic protein 4; Negatively regulates the structure and function of the limb apical ectodermal ridge. (404 aa) |
| | TDRD7 | Tudor domain-containing protein 7; Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of specific genes in the developing lens. Also required during spermatogenesis. (1095 aa) |
| | EP300 | E1A binding protein p300. (2450 aa) |
| | TBXT | T-box transcription factor T; Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. (433 aa) |
| | WLS | Protein wntless homolog; May play an essential role in Wnt signaling pathway. May be required for Wnt-dependent patterning processes (By similarity). Belongs to the wntless family. (541 aa) |
| | HOXA9 | Homeobox protein Hox-A9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (260 aa) |
| | HOXA10 | Homeobox domain-containing protein. (364 aa) |
| | LRP2 | LDL receptor related protein 2. (3187 aa) |
| | MEOX2 | Homeobox domain-containing protein. (302 aa) |
| | GNOT2 | Homeobox domain-containing protein. (167 aa) |
| | INTU | Uncharacterized protein. (322 aa) |
| | DMRT3 | Doublesex and mab-3 related transcription factor 3. (466 aa) |
| | FRS2 | IRS-type PTB domain-containing protein. (508 aa) |
| | IFT140 | WD_REPEATS_REGION domain-containing protein. (1453 aa) |
| | FEZF1 | FEZ family zinc finger 1. (438 aa) |
| | NEUROD1 | Neurogenic differentiation factor 1; Acts as a transcriptional activator. Mediates transcriptional activation by binding to E box-containing promoter. Acts as a differentiation factor during neurogenesis. Induces photoreceptor cell overproduction in vivo and de novo generation in vitro. May play a role in photoreceptor cell production. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. (357 aa) |
| | ABI1 | Uncharacterized protein. (507 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (709 aa) |
| | LHX5 | LIM homeobox protein 5. (402 aa) |
| | MESP2 | BHLH domain-containing protein. (323 aa) |
| | RELN | Reelin; Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity); Belongs to the reel [...] (3462 aa) |
| | SUFU | Suppressor of fused homolog. (484 aa) |
| | DPCD | Uncharacterized protein. (209 aa) |
| | CDX4 | Homeobox protein CHOX-CAD2; Belongs to the Caudal homeobox family. (263 aa) |
| | TRA2B | Transformer-2 beta. (289 aa) |
| | ENSGALP00000073802 | Uncharacterized protein. (524 aa) |
| | MYF6 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. (341 aa) |
| | FAM76A | Protein FAM76A; Belongs to the FAM76 family. (402 aa) |
| | BHLHE41 | Basic helix-loop-helix family member e41. (440 aa) |
| | TMED2 | GOLD domain-containing protein. (208 aa) |
| | HEYL | Hes related family bHLH transcription factor with YRPW motif like. (319 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) |
| | RPGRIP1L | RPGRIP1 like. (1273 aa) |
| | HELT | Helt bHLH transcription factor. (240 aa) |
| | RNF2 | Ring finger protein 2. (336 aa) |
| | HEY1 | Hes related family bHLH transcription factor with YRPW motif 1. (488 aa) |
| | ACVRL1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (796 aa) |
| | DISP1 | Dispatched RND transporter family member 1. (1640 aa) |
| | TDRD1 | Tudor domain containing 1. (1035 aa) |
| | HES6 | Hes family bHLH transcription factor 6. (242 aa) |
| | EMX2 | Empty spiracles homeobox 2. (336 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (893 aa) |
| | ETS2 | Protein C-ets-2; Probable transcription factor; Belongs to the ETS family. (479 aa) |
| | SEMA3C | Semaphorin-3C; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (751 aa) |
| | SETDB2 | SET domain bifurcated histone lysine methyltransferase 2. (795 aa) |
| | HES2 | Hes family bHLH transcription factor 2. (99 aa) |
| | TSHZ1 | Teashirt zinc finger homeobox 1. (1076 aa) |
| | EPB41L5 | Erythrocyte membrane protein band 4.1 like 5. (766 aa) |
| | LEF1 | HMG box domain-containing protein. (412 aa) |
| | AXIN1 | Axin-1; Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. (841 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa) |
| | WNT1 | Protein Wnt-1; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation. Developmental protein that promotes cell proliferation in the developing spinal cord. Has a role in osteoblast function, bone development and bone homeostasis (By similarity). (550 aa) |
| | TMEM107 | Uncharacterized protein. (159 aa) |
| | CTNNBIP1 | ICAT domain-containing protein. (81 aa) |
| | OTX1 | Orthodenticle homeobox 1. (335 aa) |
| | BTG2 | BTG anti-proliferation factor 2. (164 aa) |
| | HOXB4 | Homeobox protein Hox-B4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. Deformed subfamily. (245 aa) |
| | HOXC11 | Homeobox C11. (193 aa) |
| | PLD6 | Phospholipase D family member 6. (218 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (193 aa) |
| | TSKU | Tsukushin; Dorsalizing factor involved in the induction of Hensen node. Functions as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation. (369 aa) |
| | WNT11 | Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters. (354 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | HES5 | Hairy and enhancer of split 5. (157 aa) |
| | MEOX1 | Homeobox domain-containing protein. (240 aa) |
| | HOXB9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (273 aa) |
| | LHX3 | LIM/homeobox protein Lhx3; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with LIM-1, ISL-1 and ISL-2. (395 aa) |
| | NKX2-5 | Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Binds to the core DNA motif of promoter. Belongs to the NK-2 homeobox family. (294 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling. Controls somitogenesis by sequestering the BMP-4 activity which in turn differentiates distinct subtypes of the mesoderm along the mediolateral axis. (387 aa) |
| | ZFR2 | DZF domain-containing protein. (1067 aa) |
| | DNAAF1 | Dynein assembly factor 1, axonemal. (516 aa) |
| | FN1 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). (2526 aa) |
| | DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (240 aa) |
| | LEUTX | Homeobox domain-containing protein. (403 aa) |
| | DLX1 | Homeodomain transcription factor DLX1. (255 aa) |
| | NLE1 | Notchless homolog 1. (482 aa) |
| | C1QA | Complement C1q A chain. (243 aa) |
| | FOXN4 | Forkhead box N4. (513 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | EPHA4 | Ephrin type-A receptor 4; Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI- anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. U [...] (986 aa) |
| | LHX1 | LIM/homeobox protein Lhx1; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with ISL-2. (406 aa) |
| | CER1 | Cerberus; Cytokine that acts as a regulator of the activity of Nodal/BMP pathways during the establishment of bilateral asymmetry in the head and trunk of the embryo; Belongs to the DAN family. (272 aa) |
| | HNF1B | HNF1 homeobox B. (531 aa) |
| | CDX1 | Homeobox protein CDX-1; Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1. Binds to the PRKD1 promoter. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA. Belongs to the Caudal homeobox family. (260 aa) |
| | FBXL15 | F-box and leucine rich repeat protein 15. (299 aa) |
| | PALB2 | Partner and localizer of BRCA2. (1341 aa) |
| | SHH | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (425 aa) |
| | RFX4 | Regulatory factor X4. (743 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (686 aa) |
| | HOXD8 | Homeobox protein Hox-D8. (268 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (124 aa) |
| | HOXA5 | Homeobox protein Hox-A5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' (By similarity); Belongs to the Antp homeobox family. (318 aa) |
| | ENSGALP00000062625 | Uncharacterized protein. (251 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | ENSGALP00000061859 | Uncharacterized protein. (275 aa) |
| | TLL1 | Tolloid-like protein 1; Protease which processes procollagen C-propeptides, such as chordin, probiglycan and prolysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis (By similarity). (1040 aa) |
| | HOXA7 | Homeobox protein Hox-A7; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (219 aa) |
| | TDRD6 | Tudor domain containing 6. (1604 aa) |
| | MTHFSD | Methenyltetrahydrofolate synthetase domain containing. (321 aa) |
| | HES4 | Transcription factor HES-1; Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). (290 aa) |
| | GSC | Homeobox protein goosecoid; Involved in the development of the organizer region in the gastrula (Hensen node in chicken). (346 aa) |
| | HOXC5 | Homeobox domain-containing protein. (222 aa) |
| | WDR19 | WD_REPEATS_REGION domain-containing protein. (470 aa) |
| | LHX4 | LIM homeobox 4. (533 aa) |
| | HOXB6 | Homeobox protein Hox-B6; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (222 aa) |
| | TDRD5 | Tudor domain containing 5. (742 aa) |
| | ENSGALP00000058348 | Uncharacterized protein. (692 aa) |
| | SIX3 | Homeobox protein SIX3; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon. Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression. In addition, Six3 activity is re [...] (314 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa) |
| | CYP26C1 | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (510 aa) |
| | TBX2 | T-box transcription factor 2. (693 aa) |
| | WNT3A | Protein Wnt-3a; [Isoform 1]: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family. Regulates chick apical ectodermal ridge formation. Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). ECO:0000250|UniProtKB:P56704. (376 aa) |
| | HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (335 aa) |
| | DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4301 aa) |
| | CLUAP1 | Uncharacterized protein. (412 aa) |
| | NOTO | Gnot1 homeodomain protein. (171 aa) |
| | IRX1 | Homeobox domain-containing protein. (467 aa) |
| | TCTN1 | Tectonic family member 1. (565 aa) |
| | HOXC9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (262 aa) |
| | NKX2-2 | Homeobox domain-containing protein. (272 aa) |
| | AXIN2 | Uncharacterized protein. (837 aa) |
| | HOXC10 | Homeobox domain-containing protein. (354 aa) |
| | FOXG1 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. (451 aa) |
| | SRF | Serum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | HOXD13 | Homeobox protein Hox-D13; Sequence-specific transcription factor that binds gene promoters and activates their transcription (By similarity). Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (303 aa) |
| | LDB1 | LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. (416 aa) |
| | LOC427010 | DZF domain-containing protein. (1096 aa) |
| | GRSF1 | G-rich RNA sequence binding factor 1. (467 aa) |
| | LRP4 | LDL receptor related protein 4. (1911 aa) |
| | LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1580 aa) |
| | EN1 | Homeobox protein engrailed-1. (334 aa) |
| | MDFI | MyoD family inhibitor. (161 aa) |
| | HSPB11 | F5/8 type C domain-containing protein. (141 aa) |
| | EMX1 | Empty spiracles homeobox 1. (235 aa) |
| | DLX2 | Distal-less homeobox 2. (253 aa) |
| | TBX20 | T-box transcription factor TBX20; Acts as a transcriptional regulator involved in heart developmental processes. (440 aa) |
| | GBX2 | Homeobox protein GBX-2; May act as a transcription factor for cell pluripotency and differentiation in the embryo. (339 aa) |
| | HOXB7 | Homeobox B7. (217 aa) |
| | HHIP | Hedgehog interacting protein. (697 aa) |
| | PGAP1 | Post-GPI attachment to proteins 1. (866 aa) |
| | HOXC8 | Homeobox protein Hox-C8; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (242 aa) |
| | HOXB3 | Homeobox protein Hox-B3; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (399 aa) |
| | CHRD | Uncharacterized protein. (1208 aa) |
| | SOX1 | Transcription factor SOX-1; Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural protein and suppresses neuronal differentiation. (373 aa) |
| | PTN | Pleiotrophin; Secreted growth factor that mediates its signal through cell- surface proteoglycan and non-proteoglycan receptors (By similarity). Binds cell-surface proteoglycan receptor via their chondroitin sulfate (CS) groups (By similarity). Thereby regulates many processes like cell proliferation, cell survival, cell growth, cell differentiation and cell migration (By similarity); Belongs to the pleiotrophin family. (165 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog 6; Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling, preventing NF-kappa-B activation, and BMP-SMAD1 signaling pathway. Binds to regulatory elements in target promoter regions (By similarity). (431 aa) |
| | COBL | Cordon-bleu WH2 repeat protein. (1412 aa) |
| | GSX2 | GS homeobox 2. (263 aa) |
| | ADGRG1 | Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (695 aa) |
| | SMO | Smoothened homolog; G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). (816 aa) |
| | HOXB5 | Homeobox protein Hox-B5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (264 aa) |
| | ZBTB32 | Uncharacterized protein. (665 aa) |
| | GLI3 | Transcriptional repressor GLI3R; Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. (1576 aa) |
| | DDIT3 | C/EBP-like protein. (155 aa) |
| | TLL2 | Metalloendopeptidase. (978 aa) |
| | TBR1 | T-box brain transcription factor 1. (677 aa) |
| | TDRKH | Tudor and KH domain containing. (559 aa) |
| | HOXC4 | Homeobox C4. (379 aa) |
| | IRX3 | Iroquois homeobox 3. (445 aa) |
| | HOXC6 | Homeobox C6. (271 aa) |
| | HOXC13 | Homeobox C13. (295 aa) |
| | LOC420748 | Uncharacterized protein. (792 aa) |
| | ACVR1 | Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin (By similarity). (524 aa) |
| | PITX2 | Pituitary homeobox 2; May play an important role in development and maintenance of anterior structures. May play a role in determining left-right asymmetry and in vasculogenesis during avian embryogenesis. (333 aa) |
| | NOG2 | Noggin; Belongs to the noggin family. (207 aa) |
| | HOXA11 | Homeobox protein Hox-A11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (297 aa) |
| | HAND2 | Heart- and neural crest derivatives-expressed protein 2; Essential for cardiac morphogenesis. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity). Plays an important role in limb development, particularly in the establishment of anterior-posterior polarization of the limb bud. (216 aa) |
| | CTNNB1 | Uncharacterized protein. (781 aa) |
| | SOX2 | Transcription factor SOX-2; Transcriptional activator. Binds to the consensus DNA sequence 5'-TCATTGTTGTTG-3'. In cooperation with other transcription factors, binds to the promoter sequence of the crystallin gene to activate transcription in the lens. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. May function as a switch in neuronal development. (312 aa) |
| | OTX2 | Homeodomain transcription factor. (289 aa) |
| | NRP2 | Uncharacterized protein. (969 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Essential mediator of somite segmentation and patterning. (363 aa) |
| | SEMA3F | Sema domain-containing protein; Belongs to the semaphorin family. (838 aa) |
| | TBX3 | T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. (732 aa) |
| | PCSK6 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (1024 aa) |
| | CHTOP | Mothers against decapentaplegic homolog. (445 aa) |
| | BPTF | Uncharacterized protein. (744 aa) |
| | TASOR | Transcription activation suppressor. (1709 aa) |
| | IFT52 | Uncharacterized protein. (489 aa) |
| | OTX5 | Orthodenticle-related homeobox 5. (287 aa) |
| | MYF5 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). (258 aa) |
| | ISL1 | Insulin gene enhancer protein ISL-1; Acts as a transcriptional regulator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA- 3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to insulin gene enhancer sequences (By similarity). Defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with LHX1, LHX3 and ISL2. Binds to insulin gene enhancer sequences (By similarity). Essential for heart d [...] (349 aa) |
| | HES6-2 | Uncharacterized protein. (227 aa) |
| | HES1 | Transcription factor HES-1. (257 aa) |
| | HOXA6 | Homeobox protein Hox-A6; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (231 aa) |
| | LOC107057363 | Uncharacterized protein. (197 aa) |
| | HOXA3 | Homeobox protein Hox-A3; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (413 aa) |
| | EOMES | T-box_assoc domain-containing protein. (661 aa) |
| | XRCC2 | X-ray repair cross complementing 2. (279 aa) |
| | DZIP1L | DAZ interacting zinc finger protein 1 like. (470 aa) |
| | HOXCDX1L | Homeobox domain-containing protein. (270 aa) |
| | POFUT1 | Uncharacterized protein POFUT1. (380 aa) |
| | CRB2 | Uncharacterized protein. (1469 aa) |
| | HOXD3 | Homeobox D3. (413 aa) |
| | HOXD4 | Homeobox protein Hox-D4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'; Belongs to the Antp homeobox family. Deformed subfamily. (237 aa) |
| | HOXD10 | Homeobox protein Hox-D10; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (339 aa) |
| | AIDA | Uncharacterized protein. (306 aa) |
| | TTC21B | Tetratricopeptide repeat domain 21B. (1411 aa) |
| | LOC430303 | Uncharacterized protein. (2034 aa) |
| | GREM1 | Gremlin-1; Cytokine that may play a role in the development of the medial pallium and during optic nerve and pecten development by modulating BMP signaling. (184 aa) |
| | BMPR1B | Bone morphogenetic protein receptor type-1B; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptiona (By similarity). Positively regulates chondrocyte differentiation. (502 aa) |
| | LOC419390 | Uncharacterized protein. (161 aa) |
| | FGF8 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Involved in initiation, outgrowth and patterning of the limbs; Belongs to the heparin-binding growth factors family. (214 aa) |
| | RNF220 | RING-type domain-containing protein. (305 aa) |
| | TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (412 aa) |
| | HOXD9 | Homeobox protein Hox-D9; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (302 aa) |
| | HOXA4 | Homeobox protein Hox-A4; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds to sites in the 5'-flanking sequence of its coding region with various affinities. The consensus sequences of the high and low affinity binding sites are 5'-TAATGA[CG]-3' and 5'-CTAATTTT-3'. (457 aa) |
| | GAS1 | Growth arrest specific 1. (159 aa) |
| | FAM76B | Family with sequence similarity 76 member B. (341 aa) |
| | ATM | Non-specific serine/threonine protein kinase. (3050 aa) |
| | C1H2ORF49 | Ashwin; Belongs to the ashwin family. (241 aa) |
| | IFT172 | Intraflagellar transport 172. (1749 aa) |
| | TDRD15 | Tudor domain containing 15. (1994 aa) |
