(19 nodes) Positive regulation of vascular endothelial growth factor production network (Gallus gallus)

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Predicted Interactions

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Your Input:
	IL6	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa)
	BSG	Basigin; Plays an important role in targeting monocarboxylate transporters to the plasma membrane (By similarity). Probable receptor involved in cell surface recognition at the blood-brain barrier. Involved in neuronal-glial interactions in retinal development. (388 aa)
	BRCA1	Uncharacterized protein. (1749 aa)
	SULF2	Extracellular sulfatase. (873 aa)
	FLT4	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1378 aa)
	C3AR1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (461 aa)
	IL6ST	Glycoprotein 130. (918 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (1085 aa)
	ADORA2B	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (340 aa)
	ATF4	ATF4. (354 aa)
	ISL1	Insulin gene enhancer protein ISL-1; Acts as a transcriptional regulator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA- 3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to insulin gene enhancer sequences (By similarity). Defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with LHX1, LHX3 and ISL2. Binds to insulin gene enhancer sequences (By similarity). Essential for heart d [...] (349 aa)
	CCBE1	Collagen and calcium binding EGF domains 1. (329 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
	IL1B	Interleukin-1; Belongs to the IL-1 family. (267 aa)
	C5	Complement C5. (1758 aa)
	SULF1	Sulfatase 1. (862 aa)
	CYP1C1	Uncharacterized protein; Belongs to the cytochrome P450 family. (516 aa)
	C5AR1	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	ENSGALP00000072609	Uncharacterized protein. (215 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	EIF2AK3	ENSGALP00000037099	ENSGALP00000025668	ATF4.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.961
BRCA1	IL1B	ENSGALP00000004383	ENSGALP00000050171	Uncharacterized protein.	Interleukin-1; Belongs to the IL-1 family.	0.533
C3AR1	C5	ENSGALP00000021561	ENSGALP00000050353	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Complement C5.	0.752
C3AR1	C5AR1	ENSGALP00000021561	ENSGALP00000066054	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.541
C5	C3AR1	ENSGALP00000050353	ENSGALP00000021561	Complement C5.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.752
C5	C5AR1	ENSGALP00000050353	ENSGALP00000066054	Complement C5.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.978
C5AR1	C3AR1	ENSGALP00000066054	ENSGALP00000021561	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.541
C5AR1	C5	ENSGALP00000066054	ENSGALP00000050353	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Complement C5.	0.978
CCBE1	FLT4	ENSGALP00000043340	ENSGALP00000009174	Collagen and calcium binding EGF domains 1.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.774
EIF2AK3	ATF4	ENSGALP00000025668	ENSGALP00000037099	Eukaryotic translation initiation factor 2 alpha kinase 3.	ATF4.	0.961
ENSGALP00000072609	SULF1	ENSGALP00000072609	ENSGALP00000054958	Uncharacterized protein.	Sulfatase 1.	0.899
FLT4	CCBE1	ENSGALP00000009174	ENSGALP00000043340	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Collagen and calcium binding EGF domains 1.	0.774
IL1B	BRCA1	ENSGALP00000050171	ENSGALP00000004383	Interleukin-1; Belongs to the IL-1 family.	Uncharacterized protein.	0.533
IL1B	IL6	ENSGALP00000050171	ENSGALP00000068117	Interleukin-1; Belongs to the IL-1 family.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.991
IL6	IL1B	ENSGALP00000068117	ENSGALP00000050171	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	Interleukin-1; Belongs to the IL-1 family.	0.991
IL6	IL6ST	ENSGALP00000068117	ENSGALP00000023682	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	Glycoprotein 130.	0.997
IL6ST	IL6	ENSGALP00000023682	ENSGALP00000068117	Glycoprotein 130.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.997
SULF1	ENSGALP00000072609	ENSGALP00000054958	ENSGALP00000072609	Sulfatase 1.	Uncharacterized protein.	0.899