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| | SIRT6 | Deacetylase sirtuin-type domain-containing protein. (378 aa) |
| | GNRH1 | GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; Belongs to the GnRH family. (92 aa) |
| | CRHR1 | Corticotropin-releasing factor receptor 1; G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. (420 aa) |
| | EDN2 | Endothelin-2. (179 aa) |
| | NR0B2 | NR LBD domain-containing protein. (262 aa) |
| | SNX19 | Sorting nexin 19. (981 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | C1QTNF12 | C1q and TNF related 12. (320 aa) |
| | AANAT | Serotonin N-acetyltransferase; Catalyzes the N-acetylation of serotonin into N- acetylserotonin; Belongs to the acetyltransferase family. AANAT subfamily. (205 aa) |
| | DGKQ | Diacylglycerol kinase. (904 aa) |
| | HSD17B4 | 17-beta-hydroxysteroid dehydrogenase type IV. (735 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (790 aa) |
| | C26H6ORF125 | Uncharacterized protein. (125 aa) |
| | AACS | Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity). (743 aa) |
| | PRLHRL | Prolactin-releasing peptide receptor-like protein. (344 aa) |
| | GALR1L | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | LOC425137 | Aldo_ket_red domain-containing protein. (316 aa) |
| | GHRH | GHRH/PACAP-like. (172 aa) |
| | PRMT3 | Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (526 aa) |
| | GPER1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | GPR119 | G protein-coupled receptor 119. (320 aa) |
| | DHCR7 | Uncharacterized protein. (474 aa) |
| | ADAM10 | Uncharacterized protein. (749 aa) |
| | PSMD9 | PDZ domain-containing protein. (207 aa) |
| | CHST8 | Carbohydrate sulfotransferase. (430 aa) |
| | NDST2 | Uncharacterized protein. (879 aa) |
| | AQP1 | Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa) |
| | GHRHR | G protein-coupled pituitary GHRH receptor; Belongs to the G-protein coupled receptor 2 family. (419 aa) |
| | CACNA1H | Calcium voltage-gated channel subunit alpha1 H. (1435 aa) |
| | SOX8 | Transcription factor SOX-8; May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'. (470 aa) |
| | SYT9 | Synaptotagmin 9. (528 aa) |
| | DHRS11 | Dehydrogenase/reductase SDR family member 11; Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta- hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones. (255 aa) |
| | BCO1 | Beta,beta-carotene 15,15'-dioxygenase; Symmetrically cleaves beta-carotene into two molecules of retinal using a dioxygenase mechanism; Belongs to the carotenoid oxygenase family. (526 aa) |
| | HSD17B2 | Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (384 aa) |
| | HNF1B | HNF1 homeobox B. (531 aa) |
| | TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1508 aa) |
| | PASK | PAS domain containing serine/threonine kinase. (1348 aa) |
| | ABCC8 | ATP binding cassette subfamily C member 8. (1595 aa) |
| | SCNN1B | Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (667 aa) |
| | RBP4A | Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. Belongs to the calycin superfamily. Lipocalin family. (196 aa) |
| | FAM3D | Family with sequence similarity 3 member D. (226 aa) |
| | EGR1 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (510 aa) |
| | SLC16A2 | Uncharacterized protein. (538 aa) |
| | DRD2 | Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa) |
| | ACSL4 | Acyl-CoA synthetase long chain family member 4. (670 aa) |
| | FURIN | Trans Golgi network protease furin; Belongs to the peptidase S8 family. (789 aa) |
| | GHRL | Preproghrelin. (116 aa) |
| | TRH | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. (260 aa) |
| | CREB1 | cAMP response element-binding protein. (327 aa) |
| | KLF7 | Uncharacterized protein. (296 aa) |
| | LOC101747844 | Carbohydrate sulfotransferase. (316 aa) |
| | NEUROD1 | Neurogenic differentiation factor 1; Acts as a transcriptional activator. Mediates transcriptional activation by binding to E box-containing promoter. Acts as a differentiation factor during neurogenesis. Induces photoreceptor cell overproduction in vivo and de novo generation in vitro. May play a role in photoreceptor cell production. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. (357 aa) |
| | CCDC186 | Coiled-coil domain containing 186. (919 aa) |
| | SRI | Uncharacterized protein. (297 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (728 aa) |
| | SNAP23 | Synaptosomal-associated protein; Belongs to the SNAP-25 family. (209 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (704 aa) |
| | FGG | Fibrinogen C-terminal domain-containing protein. (438 aa) |
| | RAB11FIP2 | RAB11 family interacting protein 2. (510 aa) |
| | RDH11 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa) |
| | SCG5 | Uncharacterized protein. (208 aa) |
| | SELENOT | Thioredoxin reductase-like selenoprotein T; Selenoprotein with thioredoxin reductase-like oxidoreductase activity; Belongs to the SelWTH family. Selenoprotein T subfamily. (199 aa) |
| | AIMP1 | Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (317 aa) |
| | SRD5A2 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (255 aa) |
| | DIO1 | Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). (229 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa) |
| | CYP46A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (499 aa) |
| | RPE65 | Retinoid isomerohydrolase; Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore. Essential for the production of 11-cis retinal for both rod and cone photoreceptors (By similarity). Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye- specific carotenoid. The soluble form binds v [...] (530 aa) |
| | CYP27C1 | Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (416 aa) |
| | NR1H4 | Farnesoid X receptor. (473 aa) |
| | SULT1B | Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa) |
| | SULT1B1 | Sulfotransferase family cytosolic 1B member 1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates thyroid hormones including 3,3'-diiodothyronine, catechols such as 4-nitrocatechol and 4-isopropylcatechol and phenols such as 2-bromophenol. (296 aa) |
| | SULT1E1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (294 aa) |
| | DHRS7 | Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa) |
| | SNX4 | Sorting nexin 4. (435 aa) |
| | PLA2G6 | Uncharacterized protein. (796 aa) |
| | IYD | Iodotyrosine deiodinase. (277 aa) |
| | BMP4 | Bone morphogenetic protein 4; Negatively regulates the structure and function of the limb apical ectodermal ridge. (404 aa) |
| | PRL | Prolactin. (229 aa) |
| | EDN1 | Endothelin 1. (194 aa) |
| | IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex fo [...] (153 aa) |
| | BMP6 | Bone morphogenetic protein 6. (434 aa) |
| | AKR1D1 | Aldo_ket_red domain-containing protein. (448 aa) |
| | SRD5A1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (266 aa) |
| | AKR1B1 | Aldo_ket_red domain-containing protein. (331 aa) |
| | LOC418170 | Aldo_ket_red domain-containing protein. (314 aa) |
| | AKR1B10 | Aldo-keto reductase. (317 aa) |
| | TMF1 | TATA element modulatory factor 1. (1105 aa) |
| | VIP | Intestinal peptide PHI-27-like; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder; Belongs to the glucagon family. (200 aa) |
| | ALDH8A1 | Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa) |
| | CORIN | Corin, serine peptidase. (1130 aa) |
| | PNPLA2 | PNPLA2/ATGL. (483 aa) |
| | PCSK1 | Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (748 aa) |
| | RFX6 | Regulatory factor X6. (916 aa) |
| | GCNT4 | Glucosaminyl (N-acetyl) transferase 4. (455 aa) |
| | CRHBP | Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (345 aa) |
| | DDO | D-aspartate oxidase. (342 aa) |
| | TTR | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (168 aa) |
| | ALDH1A1 | Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo (By similarity). (509 aa) |
| | PCSK5 | Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1864 aa) |
| | MPC2 | Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (133 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa) |
| | TPO | Thyroid peroxidase. (863 aa) |
| | PNPLA4 | PNPLA domain-containing protein. (350 aa) |
| | BLK | Tyrosine-protein kinase. (526 aa) |
| | ASMT | Acetylserotonin O-methyltransferase; Catalyzes the transfer of a methyl group onto N- acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. (346 aa) |
| | MTNR1B | Melatonin receptor type 1B; High affinity receptor for melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibits adenylate cyclase activity (By similarity). (361 aa) |
| | FZD4 | Frizzled-4; Receptor for Wnt proteins (By similarity). Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 ki [...] (525 aa) |
| | RDH14 | Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (326 aa) |
| | KCNJ11 | Potassium voltage-gated channel subfamily J member 11. (397 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) |
| | PRLHR | G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa) |
| | GCG | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. (206 aa) |
| | CYP17A1 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. (527 aa) |
| | KCNB1 | Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (863 aa) |
| | CRABP1 | Cellular retinoic acid-binding protein 1; Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors. (137 aa) |
| | EDNRB | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (560 aa) |
| | ERD2L | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa) |
| | NPVF | Gonadotropin-inhibitory hormone. (173 aa) |
| | BIRC5 | Uncharacterized protein. (142 aa) |
| | PIM3 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (323 aa) |
| | NIBAN2 | Niban apoptosis regulator 2. (898 aa) |
| | ACE | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. (1281 aa) |
| | STC2 | Stanniocalcin 2. (306 aa) |
| | GHSR | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (561 aa) |
| | TNFSF11 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (400 aa) |
| | AKR1E2 | Aldo_ket_red domain-containing protein. (316 aa) |
| | GALR1 | Galanin receptor; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | NDUFAF2 | Uncharacterized protein. (171 aa) |
| | CPLX3 | Uncharacterized protein. (157 aa) |
| | FGF23 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (254 aa) |
| | INHBB | Inhibin beta B chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. (392 aa) |
| | FFAR4 | Free fatty acid receptor 4. (349 aa) |
| | CRABP2 | Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | MAFA | Transcription factor MafA; Transcription factor involved in transcription regulation during lens development, including that of crystallin and filensin/BFSP1 genes. Binds to CRE-type MARE 5'- TGCTGACGTCAGCA-3' and TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequences ; Belongs to the bZIP family. Maf subfamily. (286 aa) |
| | GLUD2 | Glutamate dehydrogenase 1, mitochondrial; Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (By similarity). (553 aa) |
| | ECE1 | Endothelin converting enzyme-1. (752 aa) |
| | ENSGALP00000044025 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (617 aa) |
| | CEL | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (555 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | INHBA | Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. Induces somatostatin in the ciliary ganglion neurons and may [...] (424 aa) |
| | CYP21A1 | Steroid 21-hydroxylase; Belongs to the cytochrome P450 family. (478 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (662 aa) |
| | CHTOP | Mothers against decapentaplegic homolog. (445 aa) |
| | PCSK6 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (1024 aa) |
| | TBX3 | T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. (732 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (384 aa) |
| | LOC768589 | Uncharacterized protein. (173 aa) |
| | CYP26A1 | Cytochrome P450 26A1; A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomer [...] (492 aa) |
| | RDH8 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | MYRIP | Rab_eff_C domain-containing protein. (666 aa) |
| | GHR | Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway; Belongs to the type I cytokine receptor family. Type 1 subfamily. (646 aa) |
| | WNT4 | Protein Wnt-4; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development (By similarity). (351 aa) |
| | ENSGALP00000046712 | Uncharacterized protein. (1194 aa) |
| | CCN3 | CCN family member 3; Immediate-early protein likely to play a role in cell growth regulation. Its overexpression is associated with tumorigenesis and expression of a N-terminal-truncated version of CCN3 gene in chicken embryonic fibroblasts (CEF) is sufficient to induce the transformation of CEF in vitro. (351 aa) |
| | LYN | Tyrosine-protein kinase. (491 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2820 aa) |
| | IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (964 aa) |
| | PICK1 | Protein interacting with PRKCA 1. (408 aa) |
| | DUOXA2 | Uncharacterized protein. (495 aa) |
| | RDH16 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (419 aa) |
| | ENSGALP00000048186 | Uncharacterized protein. (528 aa) |
| | LOC107056277 | Uncharacterized protein. (491 aa) |
| | RBP1 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | ENSGALP00000048351 | Uncharacterized protein. (111 aa) |
| | MEP1A | Meprin A subunit. (711 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa) |
| | ECE2 | Uncharacterized protein. (814 aa) |
| | PARK7 | Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...] (189 aa) |
| | RETSAT | Uncharacterized protein. (611 aa) |
| | CCL5 | C-C motif chemokine. (90 aa) |
| | SEC11A | Signal peptidase complex catalytic subunit SEC11. (179 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa) |
| | IL1B | Interleukin-1; Belongs to the IL-1 family. (267 aa) |
| | CRH | Corticotropin releasing hormone. (167 aa) |
| | DUOXA1L | Uncharacterized protein. (322 aa) |
| | CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (508 aa) |
| | GLP1R | Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (459 aa) |
| | ENSGALP00000052517 | Zf-piccolo domain-containing protein. (470 aa) |
| | HSD17B10 | Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (418 aa) |
| | ENSA | Alpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). (117 aa) |
| | DUOX2 | Dual oxidase 2. (1533 aa) |
| | C2CD2L | SMP_C2CD2L domain-containing protein. (707 aa) |
| | SLC7A5 | Large neutral amino acids transporter small subunit 1. (526 aa) |
| | TGFB1 | Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (392 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (401 aa) |
| | RAPGEF4 | Rap guanine nucleotide exchange factor 4. (1026 aa) |
| | ADH1C | Alcohol dehydrogenase 1. (376 aa) |
| | PDX1 | Homeobox domain-containing protein. (259 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa) |
| | CYP1C1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (516 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | SEC11C | Signal peptidase complex catalytic subunit SEC11. (177 aa) |
| | SYT7 | Synaptotagmin 7. (403 aa) |
| | CHD7 | Chromodomain-helicase-DNA-binding protein 7; Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production (By similarity). (3009 aa) |
| | CAPN10 | Calpain 10; Belongs to the peptidase C2 family. (672 aa) |
| | HSD17B7 | Uncharacterized protein. (332 aa) |
| | TBX2 | T-box transcription factor 2. (693 aa) |
| | CYP26C1 | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (510 aa) |
| | NR3C2 | Mineralocorticoid receptor; Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels (By similarity). (993 aa) |
| | BFSP2 | IF rod domain-containing protein; Belongs to the intermediate filament family. (450 aa) |
| | NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. NO may serve as both a paracrine and autocrine signal for modulating osteoclast bone resorption. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2 (By similarity); Belongs to the NOS family. (1136 aa) |
| | CDV3 | Protein CDV3 homolog. (204 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa) |
| | DHRS3 | Uncharacterized protein. (302 aa) |
| | ALDH1A2 | Retinal dehydrogenase 2; Converts retinaldehyde to retinoic acid. Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal. Displays complete lack of activity with citral. (499 aa) |
| | HNF1A | Hepatocyte nuclear factor 1-alpha; Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. May participate in the control of the hormone-dependent expression of the lysozyme gene in the oviduct and liver. In liver it could repress the gene while in oviduct it may act as an activator. Belongs to the HNF1 homeobox family. (634 aa) |
| | HADH | Uncharacterized protein. (350 aa) |
| | ENSGALP00000062532 | Aldo_ket_red domain-containing protein. (143 aa) |
| | ADCYAP1 | Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family. (172 aa) |
| | POMC | Uncharacterized protein. (251 aa) |
| | LOC112531842 | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa) |
| | CRYM | Crystallin mu. (252 aa) |
| | HMGN2P46 | High mobility group nucleosome-binding domain-containing protein 3. (140 aa) |
| | STXBP3 | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (601 aa) |
| | MIDN | Midnolin. (444 aa) |
| | SLC16A10 | MFS domain-containing protein. (505 aa) |
| | ENSGALP00000065650 | Uncharacterized protein. (124 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (495 aa) |
| | GIP | GLUCAGON domain-containing protein. (139 aa) |
| | SELENOM | Sep15_SelM domain-containing protein. (152 aa) |
| | IL11 | Interleukin 11. (195 aa) |
| | ENSGALP00000066347 | COesterase domain-containing protein. (363 aa) |
| | REST | Uncharacterized protein. (339 aa) |
| | PCSK4 | Proprotein convertase subtilisin/kexin type 4. (791 aa) |
| | STXBP4 | Syntaxin binding protein 4. (736 aa) |
| | CYB5R4 | Cytochrome b5 reductase 4. (523 aa) |
| | PCSK2 | Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (644 aa) |
| | ENSGALP00000067845 | Uncharacterized protein. (285 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa) |
| | FFAR2L | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | DISP1 | Dispatched RND transporter family member 1. (1640 aa) |
| | HTR2C | 5-hydroxytryptamine (Serotonin) receptor 2C. (472 aa) |
| | DIO2 | Type II iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development. (279 aa) |
| | LIPE | HSL_N domain-containing protein. (491 aa) |
| | CRHR2 | Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (427 aa) |
| | GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) |
| | PNPLA3 | Patatin like phospholipase domain containing 3. (543 aa) |
| | LOC772005 | Uncharacterized protein. (348 aa) |
| | RAB11FIP3 | RAB11 family interacting protein 3. (689 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (678 aa) |
| | LOC107050658 | Free fatty acid receptor 2-like. (367 aa) |
| | ENSGALP00000069955 | Uncharacterized protein. (496 aa) |
| | HSD3B1 | 3Beta_HSD domain-containing protein. (484 aa) |
| | GRP | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (Probable). Stimulates pancreatic protein and fluid secretion, and increases acid secretion from the avian proventriculus. Belongs to the bombesin/neuromedin-B/ranatensin family. (164 aa) |
| | CPQ | Peptidase_M28 domain-containing protein. (469 aa) |
| | STARD3 | StAR related lipid transfer domain containing 3. (473 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (563 aa) |
| | ENSGALP00000070598 | Uncharacterized protein. (146 aa) |
| | RAB11FIP1 | RAB11 family interacting protein 1. (1259 aa) |
| | SGPL1 | Uncharacterized protein. (574 aa) |
| | TSSC1 | WD_REPEATS_REGION domain-containing protein. (395 aa) |
| | KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (863 aa) |
| | LOC107050371 | Uncharacterized protein. (1015 aa) |
| | UCN | Urocortin. (100 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (488 aa) |
| | RDH10 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (446 aa) |
| | SIRT4 | Sirtuin 4. (332 aa) |
| | EDNRB2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (479 aa) |
| | RAB44 | Uncharacterized protein. (1276 aa) |
| | DHRS13 | Dehydrogenase/reductase 13. (485 aa) |
| | DAB2 | DAB adaptor protein 2. (715 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (856 aa) |
| | DHRS12 | Uncharacterized protein. (192 aa) |
| | RETSATL | Uncharacterized protein. (342 aa) |
| | RAB11FIP5 | Uncharacterized protein. (1661 aa) |
| | RDH5 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (467 aa) |
| | SYTL4 | Synaptotagmin like 4. (690 aa) |
| | RPH3AL | Uncharacterized protein. (295 aa) |
| | GJA1 | Gap junction alpha-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Plays an essential role in gap junction communication in the ventricles. Belongs to the connexin family. Alpha-type (group II) subfamily. (381 aa) |
| | SDR16C5 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (476 aa) |
