STRINGSTRING
ZNF804A ZNF804A THY1 THY1 SNAPIN SNAPIN SEMA4G SEMA4G CX3CL1 CX3CL1 METRNL METRNL ARF6 ARF6 SEMA3A SEMA3A ZFYVE27 ZFYVE27 ISLR2 ISLR2 CNTF CNTF ANKRD27 ANKRD27 LOC425795 LOC425795 TWF1 TWF1 ENSGALP00000044407 ENSGALP00000044407 NTNG1 NTNG1 GOLGA4 GOLGA4 CRMP1 CRMP1 SEMA3F SEMA3F NGEF NGEF SLIT2 SLIT2 YTHDF1 YTHDF1 TIAM1 TIAM1 BAIAP2 BAIAP2 FBXO38 FBXO38 LYN LYN LZTS3 LZTS3 HECW1 HECW1 ITM2C ITM2C CDH15 CDH15 TBR1 TBR1 ARHGAP35 ARHGAP35 KDM1A KDM1A ULK4 ULK4 DISC1 DISC1 NTRK3 NTRK3 ALKAL2 ALKAL2 COBL COBL LOC423605 LOC423605 RAPGEF2 RAPGEF2 SEMA3E SEMA3E NELL1 NELL1 PTPRD PTPRD ULK1 ULK1 ID1 ID1 DHX36 DHX36 TWF2 TWF2 ARSJ ARSJ LRRK2 LRRK2 ABL2 ABL2 FAT3 FAT3 SDC2 SDC2 IGF2BP1 IGF2BP1 NDEL1 NDEL1 RGMA RGMA BCL11A BCL11A TIAM2 TIAM2 SRF SRF ENSGALP00000054621 ENSGALP00000054621 SEMA5B SEMA5B LOC107055431 LOC107055431 SEMA3B SEMA3B ENSGALP00000055781 ENSGALP00000055781 STMN2 STMN2 ACAP3 ACAP3 PTPRS PTPRS TMEM106B TMEM106B TRIM67 TRIM67 DBN1 DBN1 BAG5 BAG5 PTPRF PTPRF SHTN1 SHTN1 STK25 STK25 BMPR2 BMPR2 IST1 IST1 AGRN AGRN RET RET SEMA6C SEMA6C ENSGALP00000060823 ENSGALP00000060823 ANAPC2 ANAPC2 NEFL NEFL FEZ1 FEZ1 STYXL1 STYXL1 UBE3A UBE3A CAPRIN2 CAPRIN2 LOC112530215 LOC112530215 NEDD4L NEDD4L ATOH7 ATOH7 DIXDC1 DIXDC1 SEMA6D SEMA6D SEMA3C SEMA3C DBNL DBNL GSK3B GSK3B SEMA4C SEMA4C PLXNB3 PLXNB3 LDLR LDLR LOC107051305 LOC107051305 PLXNB2 PLXNB2 SEMA5A SEMA5A SEMA6B SEMA6B METRN METRN EFNB2 EFNB2 TOX TOX CDKL5 CDKL5 INPP5J-2 INPP5J-2 KIDINS220 KIDINS220 BRSK1 BRSK1 DIP2B DIP2B AMIGO3 AMIGO3 TSC1 TSC1 PLXND1 PLXND1 FST FST MYCBP2 MYCBP2 CDK5 CDK5 GATA3 GATA3 NTRK2 NTRK2 PLXNA1 PLXNA1 LOC107056280 LOC107056280 MGARP MGARP ENSGALP00000069760 ENSGALP00000069760 PSEN1 PSEN1 RAPGEF1 RAPGEF1 FYN FYN TNN TNN ENSGALP00000070245 ENSGALP00000070245 ALK ALK TXLNB TXLNB NSMF NSMF ENSGALP00000070665 ENSGALP00000070665 FKBP4 FKBP4 RTN4IP1 RTN4IP1 SLC39A12 SLC39A12 C19orf35 C19orf35 ENSGALP00000071807 ENSGALP00000071807 BDNF BDNF PLXNC1 PLXNC1 ZNF365 ZNF365 FAM134C FAM134C MAP2 MAP2 ENSGALP00000072508 ENSGALP00000072508 KEL KEL DAB2 DAB2 MAPT MAPT NCS1 NCS1 MAGI2 MAGI2 AMIGO1 AMIGO1 SRCIN1 SRCIN1 SPART SPART NGF NGF PDLIM5 PDLIM5 NFE2L2 NFE2L2 ENSGALP00000074264 ENSGALP00000074264 LPAR1 LPAR1 TMEM30A TMEM30A DSCAM DSCAM EFHC2 EFHC2 IL1RAPL1 IL1RAPL1 BMP5 BMP5 CYFIP1 CYFIP1 STK24 STK24 SLITRK1 SLITRK1 PRAG1 PRAG1 DPYSL2 DPYSL2 ISLR ISLR EPHA3 EPHA3 ROR2 ROR2 CDH2 CDH2 FIG4 FIG4 ENC1 ENC1 CAPRIN1 CAPRIN1 NTRK1 NTRK1 CREB3L2 CREB3L2 MYLIP MYLIP MBOAT1 MBOAT1 FBXO7 FBXO7 NIN NIN UST UST EP300 EP300 NDNF NDNF RUFY3 RUFY3 SCARB2 SCARB2 ROR1 ROR1 PAQR3 PAQR3 LRP8 LRP8 AMIGO2 AMIGO2 IFRD1 IFRD1 INPP5F INPP5F SNAP25 SNAP25 LTK LTK CIB4 CIB4 SEMA4B SEMA4B FBXW8 FBXW8 PAK3 PAK3 ADNP ADNP HECW2 HECW2 RTN4R RTN4R BMP7 BMP7 MAP6 MAP6 KNDC1 KNDC1 EEF2K EEF2K SEMA3D SEMA3D KIAA1024 KIAA1024 RYK RYK PLXNA4 PLXNA4 PAK2 PAK2 CRKL CRKL NEU4 NEU4 PAFAH1B1 PAFAH1B1 KREMEN1 KREMEN1 NCKIPSD NCKIPSD ARSI ARSI ULK2 ULK2 CUX2 CUX2 TRPV2 TRPV2 SEMA3G SEMA3G NEDD4 NEDD4 MFSD2A MFSD2A ABL1 ABL1 DKK1 DKK1 NTNG2 NTNG2 SETX SETX SARM1 SARM1 FN1 FN1 E1C066_CHICK E1C066_CHICK OCM OCM PRRX1 PRRX1 CRTC1 CRTC1 SEMA3DL SEMA3DL HOMER3 HOMER3 RND2 RND2 PACSIN1 PACSIN1 SEMA6A SEMA6A NPTN NPTN LRIG2 LRIG2 LZTS1 LZTS1 SEMA7A SEMA7A PLXNA2 PLXNA2 WNT3 WNT3 GFAP GFAP SF3A2 SF3A2 RAB29 RAB29 PAK1 PAK1 TANC2 TANC2 CHODL CHODL SEMA4D SEMA4D EPHB3 EPHB3 FRMD7 FRMD7 NTN1 NTN1 NELL2 NELL2 ARSB ARSB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
ZNF804AZinc finger protein 804A. (1244 aa)
THY1Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. (161 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (126 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (841 aa)
CX3CL1SCY domain-containing protein. (496 aa)
METRNLMeteorin like, glial cell differentiation regulator. (292 aa)
ARF6ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity). (175 aa)
SEMA3ASemaphorin-3A; Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to neuropilin; Belongs to the semaphorin family. (815 aa)
ZFYVE27Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. (413 aa)
ISLR2Ig-like domain-containing protein. (699 aa)
CNTFCiliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (195 aa)
ANKRD27Uncharacterized protein. (1087 aa)
LOC425795BTB domain-containing protein. (589 aa)
TWF1Uncharacterized protein. (491 aa)
ENSGALP00000044407MAM domain-containing protein. (185 aa)
NTNG1Netrin G1. (483 aa)
GOLGA4Golgin A4. (2285 aa)
CRMP1Collapsin response mediator protein-1A. (683 aa)
SEMA3FSema domain-containing protein; Belongs to the semaphorin family. (838 aa)
NGEFUncharacterized protein. (533 aa)
SLIT2Uncharacterized protein. (1533 aa)
YTHDF1YTH domain-containing protein. (561 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1594 aa)
BAIAP2BAI1 associated protein 2. (573 aa)
FBXO38F-box protein 38. (1186 aa)
LYNTyrosine-protein kinase. (491 aa)
LZTS3Leucine zipper tumor suppressor family member 3. (636 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1636 aa)
ITM2CBRICHOS domain-containing protein. (264 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (792 aa)
TBR1T-box brain transcription factor 1. (677 aa)
ARHGAP35Rho GTPase activating protein 35. (1613 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (826 aa)
ULK4Uncharacterized protein. (406 aa)
DISC1DISC1 scaffold protein. (856 aa)
NTRK3NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (By similarity). The KT and KD isoforms fail to stimulate transformation, process outgrowth or survival. Isoform KI25 exhibits tyrosine phosphorylation in the absence of ligand and is unable to mediate survival of neuronal cells. Belongs to the [...] (852 aa)
ALKAL2ALK and LTK ligand 2. (152 aa)
COBLCordon-bleu WH2 repeat protein. (1412 aa)
LOC423605Fibronectin type-III domain-containing protein. (557 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1652 aa)
SEMA3ESemaphorin-3E; Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Induces the collapse and paralysis of neuronal growth cones. Plays an important role in ensuring the specificity of synapse formation (By similarity); Belongs to the se [...] (779 aa)
NELL1Neural EGFL like 1. (761 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1963 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1081 aa)
ID1Helix-loop-helix protein. (118 aa)
DHX36DEAH-box helicase 36. (987 aa)
TWF2Twinfilin-2; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). (385 aa)
ARSJArylsulfatase family member J. (589 aa)
LRRK2Uncharacterized protein. (2557 aa)
ABL2Tyrosine-protein kinase. (1159 aa)
FAT3Uncharacterized protein. (4598 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta- actin/AC [...] (575 aa)
NDEL1Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (358 aa)
RGMARepulsive guidance molecule A; Acts as an axon-specific repulsive guidance molecule in the retinotectal system. Repulsive for a subset of axons of the temporal half of the retina. Provides thus positional information for the temporal axons invading the optic tectum in the stratum opticum. (436 aa)
BCL11AUncharacterized protein. (796 aa)
TIAM2Uncharacterized protein. (1705 aa)
SRFSerum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa)
ENSGALP00000054621Protein kinase domain-containing protein. (83 aa)
SEMA5BSemaphorin 5B. (1150 aa)
LOC107055431Uncharacterized protein. (970 aa)
SEMA3BSemaphorin 3B. (608 aa)
ENSGALP00000055781Cullin_Nedd8 domain-containing protein. (146 aa)
STMN2Stathmin-2; Is a key regulator of neurite extension through regulation of microtubule instabilily. (179 aa)
ACAP3ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. (837 aa)
PTPRSReceptor-type tyrosine-protein phosphatase S; Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (By similarity). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for norm [...] (1924 aa)
TMEM106BUncharacterized protein. (278 aa)
TRIM67Tripartite motif containing 67. (717 aa)
DBN1Drebrin; Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in synaptic plasticity (By similarity). (652 aa)
BAG5BAG family molecular chaperone regulator 5; May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. (450 aa)
PTPRFProtein tyrosine phosphatase receptor type F. (1936 aa)
SHTN1Shootin 1. (649 aa)
STK25Protein kinase domain-containing protein. (426 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa)
IST1IST1 factor associated with ESCRT-III. (366 aa)
AGRNAgrin C-terminal 110 kDa subunit; [Isoform 1]: heparan sulfate basal lamina glycoprotein that plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ) and directs key events in postsynaptic differentiation. Component of the AGRN-LRP4 receptor complex that induces the phosphorylation and activation of MUSK. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Calcium ions are required for maximal AChR clu [...] (2076 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (837 aa)
ENSGALP00000060823Ig-like domain-containing protein. (511 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (884 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (373 aa)
FEZ1Fasciculation and elongation protein zeta 1. (393 aa)
STYXL1Tyrosine-protein phosphatase domain-containing protein. (325 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (880 aa)
CAPRIN2Caprin family member 2. (1267 aa)
LOC112530215Sema domain-containing protein; Belongs to the semaphorin family. (606 aa)
NEDD4LUncharacterized protein. (1267 aa)
ATOH7Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. During retinal neurogenesis, activates its own transcription, as well as the transcription of CHRNB3 and BRN3. (151 aa)
DIXDC1DIX domain containing 1. (689 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1088 aa)
SEMA3CSemaphorin-3C; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (751 aa)
DBNLADF-H domain-containing protein. (124 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (1080 aa)
PLXNB3Sema domain-containing protein. (2202 aa)
LDLRUncharacterized protein. (302 aa)
LOC107051305Uncharacterized protein. (246 aa)
PLXNB2Plexin B2. (1781 aa)
SEMA5ASemaphorin 5A. (1076 aa)
SEMA6BSema domain-containing protein; Belongs to the semaphorin family. (870 aa)
METRNMeteorin, glial cell differentiation regulator. (294 aa)
EFNB2Ephrin-B2; Belongs to the ephrin family. (333 aa)
TOXThymocyte selection associated high mobility group box. (525 aa)
CDKL5Cyclin dependent kinase like 5. (1024 aa)
INPP5J-2SKICH domain-containing protein. (338 aa)
KIDINS220Kinase D interacting substrate 220. (1810 aa)
BRSK1Protein kinase domain-containing protein. (802 aa)
DIP2BDisco interacting protein 2 homolog B. (1572 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (494 aa)
TSC1Uncharacterized protein. (275 aa)
PLXND1Plexin D1. (1928 aa)
FSTFollistatin; Binds directly to activin and functions as an activin antagonist. Inhibits activin A signaling in the iris and regulates somatostatin phenotype in ciliary ganglion neurons. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). (320 aa)
MYCBP2MYC binding protein 2. (4755 aa)
CDK5Protein kinase domain-containing protein. (522 aa)
GATA3GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa)
NTRK2BDNF/NT-3 growth factors receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, [...] (842 aa)
PLXNA1Plexin A1. (1903 aa)
LOC107056280Uncharacterized protein. (466 aa)
MGARPMitochondria localized glutamic acid rich protein. (244 aa)
ENSGALP00000069760Uncharacterized protein. (436 aa)
PSEN1Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1225 aa)
FYNTyrosine-protein kinase Fyn; Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling. (589 aa)
TNNTenascin N. (1125 aa)
ENSGALP00000070245Uncharacterized protein. (133 aa)
ALKTyrosine-protein kinase receptor. (616 aa)
TXLNBBeta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. (693 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (513 aa)
ENSGALP00000070665Nuclear factor, erythroid 2. (326 aa)
FKBP4Peptidylprolyl isomerase. (464 aa)
RTN4IP1Reticulon 4 interacting protein 1. (389 aa)
SLC39A12Solute carrier family 39 member 12. (702 aa)
C19orf35Uncharacterized protein. (171 aa)
ENSGALP00000071807Protein kinase domain-containing protein. (93 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (254 aa)
PLXNC1Plexin C1. (1279 aa)
ZNF365Uncharacterized protein. (403 aa)
FAM134CUncharacterized protein. (435 aa)
MAP2Microtubule-associated protein. (1955 aa)
ENSGALP00000072508Uncharacterized protein. (49 aa)
KELUncharacterized protein. (720 aa)
DAB2DAB adaptor protein 2. (715 aa)
MAPTMicrotubule-associated protein. (788 aa)
NCS1Neuronal calcium sensor 1. (265 aa)
MAGI2Uncharacterized protein. (1510 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (492 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1571 aa)
SPARTSpartin. (631 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. (284 aa)
PDLIM5Uncharacterized protein. (623 aa)
NFE2L2BZIP domain-containing protein. (593 aa)
ENSGALP00000074264TIR domain-containing protein. (202 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
TMEM30ACell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...] (372 aa)
DSCAMDown syndrome cell adhesion molecule homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self- avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (By similarity). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor [...] (2034 aa)
EFHC2EF-hand domain-containing family member C2. (746 aa)
IL1RAPL1Interleukin 1 receptor accessory protein like 1. (622 aa)
BMP5BMP5. (453 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
STK24Protein kinase domain-containing protein. (333 aa)
SLITRK1SLIT and NTRK like family member 1. (692 aa)
PRAG1PEAK1 related, kinase-activating pseudokinase 1. (1315 aa)
DPYSL2Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. (676 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (422 aa)
EPHA3Ephrin type-A receptor 3; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in ca [...] (983 aa)
ROR2Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (934 aa)
CDH2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). (912 aa)
FIG4SAC domain-containing protein. (903 aa)
ENC1Ectodermal-neural cortex 1. (589 aa)
CAPRIN1Cytoplasmic activation-proliferation-associated protein 1. (702 aa)
NTRK1High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] (790 aa)
CREB3L2cAMP responsive element binding protein 3 like 2. (520 aa)
MYLIPUncharacterized protein. (445 aa)
MBOAT1Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (648 aa)
FBXO7F-box domain-containing protein. (526 aa)
NINNinein. (2081 aa)
USTUronyl 2-sulfotransferase. (409 aa)
EP300E1A binding protein p300. (2450 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
RUFY3RUN and FYVE domain containing 3. (667 aa)
SCARB2Scavenger receptor class B member 2; Belongs to the CD36 family. (481 aa)
ROR1Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (896 aa)
PAQR3Progestin and adipoQ receptor family member 3. (289 aa)
LRP8Low-density lipoprotein receptor-related protein 8; Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. Also binds alpha2-macroglobulin. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of th [...] (917 aa)
AMIGO2Ig-like domain-containing protein. (521 aa)
IFRD1Uncharacterized protein. (434 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1126 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa)
LTKTyrosine-protein kinase receptor. (558 aa)
CIB4Uncharacterized protein. (190 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (861 aa)
FBXW8F-box and WD repeat domain containing 8. (582 aa)
PAK3Non-specific serine/threonine protein kinase. (543 aa)
ADNPActivity dependent neuroprotector homeobox. (1210 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1566 aa)
RTN4RReticulon 4 receptor. (483 aa)
BMP7Bone morphogenetic protein 7. (465 aa)
MAP6Microtubule-associated protein 6 homolog; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking (By similarity). (369 aa)
KNDC1Uncharacterized protein. (1900 aa)
EEF2KEukaryotic elongation factor 2 kinase. (742 aa)
SEMA3DSemaphorin-3D; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (761 aa)
KIAA1024DD1 protein. (916 aa)
RYKReceptor like tyrosine kinase. (481 aa)
PLXNA4Plexin A4. (1892 aa)
PAK2Non-specific serine/threonine protein kinase. (521 aa)
CRKLCRK like proto-oncogene, adaptor protein. (193 aa)
NEU4Neuraminidase 4. (449 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration. (410 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
NCKIPSDNCK interacting protein with SH3 domain. (759 aa)
ARSIArylsulfatase family member I. (574 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1001 aa)
CUX2Homeobox protein cut-like. (1386 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (785 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (761 aa)
NEDD4E3 ubiquitin-protein ligase. (932 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (528 aa)
ABL1Tyrosine-protein kinase. (1111 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (240 aa)
NTNG2Netrin G2. (527 aa)
SETXSenataxin. (2801 aa)
SARM1Uncharacterized protein. (454 aa)
FN1Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). (2526 aa)
E1C066_CHICKUncharacterized protein. (258 aa)
OCMParvalbumin, thymic CPV3; Binds two calcium ions. (109 aa)
PRRX1Paired mesoderm homeobox protein 1; May participate in maintenance of mesenchymal cell lineages derived from both mesoderm and the neural crest and in patterning of the limbs and the face. (245 aa)
CRTC1CREB regulated transcription coactivator 1. (620 aa)
SEMA3DLIg-like domain-containing protein. (165 aa)
HOMER3Sema domain-containing protein; Belongs to the semaphorin family. (763 aa)
RND2Uncharacterized protein. (227 aa)
PACSIN1Protein kinase C and casein kinase substrate in neurons 1. (403 aa)
SEMA6ASemaphorin-6A isoform4; Belongs to the semaphorin family. (1044 aa)
NPTNUncharacterized protein. (397 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1055 aa)
LZTS1Leucine zipper tumor suppressor 1. (604 aa)
SEMA7ASema domain-containing protein; Belongs to the semaphorin family. (636 aa)
PLXNA2Plexin A2. (1893 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (422 aa)
SF3A2Splicing factor 3a subunit 2. (315 aa)
RAB29RAB29, member RAS oncogene family. (205 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
TANC2Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (2067 aa)
CHODLChondrolectin. (291 aa)
SEMA4DSemaphorin-4D; Cell surface receptor for PLXNB1 that plays an important role in cell-cell signaling (By similarity). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (By similarity). (855 aa)
EPHB3Ephrin type-B receptor 3; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development. In addition to its role in axon guidance plays also an important re [...] (971 aa)
FRMD7FERM domain containing 7. (686 aa)
NTN1Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors. (688 aa)
NELL2Protein NEL. (816 aa)
ARSBArylsulfatase B. (514 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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