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ZNF804A | Zinc finger protein 804A. (1244 aa) | ||||
THY1 | Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. (161 aa) | ||||
SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (126 aa) | ||||
SEMA4G | Semaphorin 4G; Belongs to the semaphorin family. (841 aa) | ||||
CX3CL1 | SCY domain-containing protein. (496 aa) | ||||
METRNL | Meteorin like, glial cell differentiation regulator. (292 aa) | ||||
ARF6 | ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity). (175 aa) | ||||
SEMA3A | Semaphorin-3A; Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to neuropilin; Belongs to the semaphorin family. (815 aa) | ||||
ZFYVE27 | Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. (413 aa) | ||||
ISLR2 | Ig-like domain-containing protein. (699 aa) | ||||
CNTF | Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. (195 aa) | ||||
ANKRD27 | Uncharacterized protein. (1087 aa) | ||||
LOC425795 | BTB domain-containing protein. (589 aa) | ||||
TWF1 | Uncharacterized protein. (491 aa) | ||||
ENSGALP00000044407 | MAM domain-containing protein. (185 aa) | ||||
NTNG1 | Netrin G1. (483 aa) | ||||
GOLGA4 | Golgin A4. (2285 aa) | ||||
CRMP1 | Collapsin response mediator protein-1A. (683 aa) | ||||
SEMA3F | Sema domain-containing protein; Belongs to the semaphorin family. (838 aa) | ||||
NGEF | Uncharacterized protein. (533 aa) | ||||
SLIT2 | Uncharacterized protein. (1533 aa) | ||||
YTHDF1 | YTH domain-containing protein. (561 aa) | ||||
TIAM1 | T cell lymphoma invasion and metastasis 1. (1594 aa) | ||||
BAIAP2 | BAI1 associated protein 2. (573 aa) | ||||
FBXO38 | F-box protein 38. (1186 aa) | ||||
LYN | Tyrosine-protein kinase. (491 aa) | ||||
LZTS3 | Leucine zipper tumor suppressor family member 3. (636 aa) | ||||
HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1636 aa) | ||||
ITM2C | BRICHOS domain-containing protein. (264 aa) | ||||
CDH15 | Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (792 aa) | ||||
TBR1 | T-box brain transcription factor 1. (677 aa) | ||||
ARHGAP35 | Rho GTPase activating protein 35. (1613 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (826 aa) | ||||
ULK4 | Uncharacterized protein. (406 aa) | ||||
DISC1 | DISC1 scaffold protein. (856 aa) | ||||
NTRK3 | NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (By similarity). The KT and KD isoforms fail to stimulate transformation, process outgrowth or survival. Isoform KI25 exhibits tyrosine phosphorylation in the absence of ligand and is unable to mediate survival of neuronal cells. Belongs to the [...] (852 aa) | ||||
ALKAL2 | ALK and LTK ligand 2. (152 aa) | ||||
COBL | Cordon-bleu WH2 repeat protein. (1412 aa) | ||||
LOC423605 | Fibronectin type-III domain-containing protein. (557 aa) | ||||
RAPGEF2 | Rap guanine nucleotide exchange factor 2. (1652 aa) | ||||
SEMA3E | Semaphorin-3E; Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Induces the collapse and paralysis of neuronal growth cones. Plays an important role in ensuring the specificity of synapse formation (By similarity); Belongs to the se [...] (779 aa) | ||||
NELL1 | Neural EGFL like 1. (761 aa) | ||||
PTPRD | Protein tyrosine phosphatase receptor type D. (1963 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (1081 aa) | ||||
ID1 | Helix-loop-helix protein. (118 aa) | ||||
DHX36 | DEAH-box helicase 36. (987 aa) | ||||
TWF2 | Twinfilin-2; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). (385 aa) | ||||
ARSJ | Arylsulfatase family member J. (589 aa) | ||||
LRRK2 | Uncharacterized protein. (2557 aa) | ||||
ABL2 | Tyrosine-protein kinase. (1159 aa) | ||||
FAT3 | Uncharacterized protein. (4598 aa) | ||||
SDC2 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa) | ||||
IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta- actin/AC [...] (575 aa) | ||||
NDEL1 | Nuclear distribution protein nudE-like 1; Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. (358 aa) | ||||
RGMA | Repulsive guidance molecule A; Acts as an axon-specific repulsive guidance molecule in the retinotectal system. Repulsive for a subset of axons of the temporal half of the retina. Provides thus positional information for the temporal axons invading the optic tectum in the stratum opticum. (436 aa) | ||||
BCL11A | Uncharacterized protein. (796 aa) | ||||
TIAM2 | Uncharacterized protein. (1705 aa) | ||||
SRF | Serum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa) | ||||
ENSGALP00000054621 | Protein kinase domain-containing protein. (83 aa) | ||||
SEMA5B | Semaphorin 5B. (1150 aa) | ||||
LOC107055431 | Uncharacterized protein. (970 aa) | ||||
SEMA3B | Semaphorin 3B. (608 aa) | ||||
ENSGALP00000055781 | Cullin_Nedd8 domain-containing protein. (146 aa) | ||||
STMN2 | Stathmin-2; Is a key regulator of neurite extension through regulation of microtubule instabilily. (179 aa) | ||||
ACAP3 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 3. (837 aa) | ||||
PTPRS | Receptor-type tyrosine-protein phosphatase S; Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (By similarity). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for norm [...] (1924 aa) | ||||
TMEM106B | Uncharacterized protein. (278 aa) | ||||
TRIM67 | Tripartite motif containing 67. (717 aa) | ||||
DBN1 | Drebrin; Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (By similarity). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in synaptic plasticity (By similarity). (652 aa) | ||||
BAG5 | BAG family molecular chaperone regulator 5; May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. (450 aa) | ||||
PTPRF | Protein tyrosine phosphatase receptor type F. (1936 aa) | ||||
SHTN1 | Shootin 1. (649 aa) | ||||
STK25 | Protein kinase domain-containing protein. (426 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa) | ||||
IST1 | IST1 factor associated with ESCRT-III. (366 aa) | ||||
AGRN | Agrin C-terminal 110 kDa subunit; [Isoform 1]: heparan sulfate basal lamina glycoprotein that plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ) and directs key events in postsynaptic differentiation. Component of the AGRN-LRP4 receptor complex that induces the phosphorylation and activation of MUSK. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Calcium ions are required for maximal AChR clu [...] (2076 aa) | ||||
RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa) | ||||
SEMA6C | Semaphorin 6C; Belongs to the semaphorin family. (837 aa) | ||||
ENSGALP00000060823 | Ig-like domain-containing protein. (511 aa) | ||||
ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (884 aa) | ||||
NEFL | Neurofilament light; Belongs to the intermediate filament family. (373 aa) | ||||
FEZ1 | Fasciculation and elongation protein zeta 1. (393 aa) | ||||
STYXL1 | Tyrosine-protein phosphatase domain-containing protein. (325 aa) | ||||
UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (880 aa) | ||||
CAPRIN2 | Caprin family member 2. (1267 aa) | ||||
LOC112530215 | Sema domain-containing protein; Belongs to the semaphorin family. (606 aa) | ||||
NEDD4L | Uncharacterized protein. (1267 aa) | ||||
ATOH7 | Protein atonal homolog 7; Transcription factor involved in the differentiation of retinal ganglion cells. During retinal neurogenesis, activates its own transcription, as well as the transcription of CHRNB3 and BRN3. (151 aa) | ||||
DIXDC1 | DIX domain containing 1. (689 aa) | ||||
SEMA6D | Semaphorin 6D; Belongs to the semaphorin family. (1088 aa) | ||||
SEMA3C | Semaphorin-3C; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (751 aa) | ||||
DBNL | ADF-H domain-containing protein. (124 aa) | ||||
GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa) | ||||
SEMA4C | Semaphorin 4C; Belongs to the semaphorin family. (1080 aa) | ||||
PLXNB3 | Sema domain-containing protein. (2202 aa) | ||||
LDLR | Uncharacterized protein. (302 aa) | ||||
LOC107051305 | Uncharacterized protein. (246 aa) | ||||
PLXNB2 | Plexin B2. (1781 aa) | ||||
SEMA5A | Semaphorin 5A. (1076 aa) | ||||
SEMA6B | Sema domain-containing protein; Belongs to the semaphorin family. (870 aa) | ||||
METRN | Meteorin, glial cell differentiation regulator. (294 aa) | ||||
EFNB2 | Ephrin-B2; Belongs to the ephrin family. (333 aa) | ||||
TOX | Thymocyte selection associated high mobility group box. (525 aa) | ||||
CDKL5 | Cyclin dependent kinase like 5. (1024 aa) | ||||
INPP5J-2 | SKICH domain-containing protein. (338 aa) | ||||
KIDINS220 | Kinase D interacting substrate 220. (1810 aa) | ||||
BRSK1 | Protein kinase domain-containing protein. (802 aa) | ||||
DIP2B | Disco interacting protein 2 homolog B. (1572 aa) | ||||
AMIGO3 | Adhesion molecule with Ig like domain 3. (494 aa) | ||||
TSC1 | Uncharacterized protein. (275 aa) | ||||
PLXND1 | Plexin D1. (1928 aa) | ||||
FST | Follistatin; Binds directly to activin and functions as an activin antagonist. Inhibits activin A signaling in the iris and regulates somatostatin phenotype in ciliary ganglion neurons. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). (320 aa) | ||||
MYCBP2 | MYC binding protein 2. (4755 aa) | ||||
CDK5 | Protein kinase domain-containing protein. (522 aa) | ||||
GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) | ||||
NTRK2 | BDNF/NT-3 growth factors receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, [...] (842 aa) | ||||
PLXNA1 | Plexin A1. (1903 aa) | ||||
LOC107056280 | Uncharacterized protein. (466 aa) | ||||
MGARP | Mitochondria localized glutamic acid rich protein. (244 aa) | ||||
ENSGALP00000069760 | Uncharacterized protein. (436 aa) | ||||
PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) | ||||
RAPGEF1 | Rap guanine nucleotide exchange factor 1. (1225 aa) | ||||
FYN | Tyrosine-protein kinase Fyn; Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling. (589 aa) | ||||
TNN | Tenascin N. (1125 aa) | ||||
ENSGALP00000070245 | Uncharacterized protein. (133 aa) | ||||
ALK | Tyrosine-protein kinase receptor. (616 aa) | ||||
TXLNB | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. (693 aa) | ||||
NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor. (513 aa) | ||||
ENSGALP00000070665 | Nuclear factor, erythroid 2. (326 aa) | ||||
FKBP4 | Peptidylprolyl isomerase. (464 aa) | ||||
RTN4IP1 | Reticulon 4 interacting protein 1. (389 aa) | ||||
SLC39A12 | Solute carrier family 39 member 12. (702 aa) | ||||
C19orf35 | Uncharacterized protein. (171 aa) | ||||
ENSGALP00000071807 | Protein kinase domain-containing protein. (93 aa) | ||||
BDNF | Brain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (254 aa) | ||||
PLXNC1 | Plexin C1. (1279 aa) | ||||
ZNF365 | Uncharacterized protein. (403 aa) | ||||
FAM134C | Uncharacterized protein. (435 aa) | ||||
MAP2 | Microtubule-associated protein. (1955 aa) | ||||
ENSGALP00000072508 | Uncharacterized protein. (49 aa) | ||||
KEL | Uncharacterized protein. (720 aa) | ||||
DAB2 | DAB adaptor protein 2. (715 aa) | ||||
MAPT | Microtubule-associated protein. (788 aa) | ||||
NCS1 | Neuronal calcium sensor 1. (265 aa) | ||||
MAGI2 | Uncharacterized protein. (1510 aa) | ||||
AMIGO1 | Adhesion molecule with Ig like domain 1. (492 aa) | ||||
SRCIN1 | SRC kinase signaling inhibitor 1. (1571 aa) | ||||
SPART | Spartin. (631 aa) | ||||
NGF | Beta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. (284 aa) | ||||
PDLIM5 | Uncharacterized protein. (623 aa) | ||||
NFE2L2 | BZIP domain-containing protein. (593 aa) | ||||
ENSGALP00000074264 | TIR domain-containing protein. (202 aa) | ||||
LPAR1 | Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa) | ||||
TMEM30A | Cell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...] (372 aa) | ||||
DSCAM | Down syndrome cell adhesion molecule homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self- avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (By similarity). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor [...] (2034 aa) | ||||
EFHC2 | EF-hand domain-containing family member C2. (746 aa) | ||||
IL1RAPL1 | Interleukin 1 receptor accessory protein like 1. (622 aa) | ||||
BMP5 | BMP5. (453 aa) | ||||
CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa) | ||||
STK24 | Protein kinase domain-containing protein. (333 aa) | ||||
SLITRK1 | SLIT and NTRK like family member 1. (692 aa) | ||||
PRAG1 | PEAK1 related, kinase-activating pseudokinase 1. (1315 aa) | ||||
DPYSL2 | Dihydropyrimidinase-related protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. (676 aa) | ||||
ISLR | Immunoglobulin superfamily containing leucine rich repeat. (422 aa) | ||||
EPHA3 | Ephrin type-A receptor 3; Receptor tyrosine kinase which binds promiscuously membrane- bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous for ephrin-A ligands it binds preferentially EFNA5. Upon activation by EFNA5 regulates cell-cell adhesion, cytoskeletal organization and cell migration. Plays a role in ca [...] (983 aa) | ||||
ROR2 | Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (934 aa) | ||||
CDH2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). (912 aa) | ||||
FIG4 | SAC domain-containing protein. (903 aa) | ||||
ENC1 | Ectodermal-neural cortex 1. (589 aa) | ||||
CAPRIN1 | Cytoplasmic activation-proliferation-associated protein 1. (702 aa) | ||||
NTRK1 | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] (790 aa) | ||||
CREB3L2 | cAMP responsive element binding protein 3 like 2. (520 aa) | ||||
MYLIP | Uncharacterized protein. (445 aa) | ||||
MBOAT1 | Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (648 aa) | ||||
FBXO7 | F-box domain-containing protein. (526 aa) | ||||
NIN | Ninein. (2081 aa) | ||||
UST | Uronyl 2-sulfotransferase. (409 aa) | ||||
EP300 | E1A binding protein p300. (2450 aa) | ||||
NDNF | Neuron derived neurotrophic factor. (568 aa) | ||||
RUFY3 | RUN and FYVE domain containing 3. (667 aa) | ||||
SCARB2 | Scavenger receptor class B member 2; Belongs to the CD36 family. (481 aa) | ||||
ROR1 | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (896 aa) | ||||
PAQR3 | Progestin and adipoQ receptor family member 3. (289 aa) | ||||
LRP8 | Low-density lipoprotein receptor-related protein 8; Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. Also binds alpha2-macroglobulin. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of th [...] (917 aa) | ||||
AMIGO2 | Ig-like domain-containing protein. (521 aa) | ||||
IFRD1 | Uncharacterized protein. (434 aa) | ||||
INPP5F | Inositol polyphosphate-5-phosphatase F. (1126 aa) | ||||
SNAP25 | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa) | ||||
LTK | Tyrosine-protein kinase receptor. (558 aa) | ||||
CIB4 | Uncharacterized protein. (190 aa) | ||||
SEMA4B | Semaphorin 4B; Belongs to the semaphorin family. (861 aa) | ||||
FBXW8 | F-box and WD repeat domain containing 8. (582 aa) | ||||
PAK3 | Non-specific serine/threonine protein kinase. (543 aa) | ||||
ADNP | Activity dependent neuroprotector homeobox. (1210 aa) | ||||
HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1566 aa) | ||||
RTN4R | Reticulon 4 receptor. (483 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (465 aa) | ||||
MAP6 | Microtubule-associated protein 6 homolog; Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking (By similarity). (369 aa) | ||||
KNDC1 | Uncharacterized protein. (1900 aa) | ||||
EEF2K | Eukaryotic elongation factor 2 kinase. (742 aa) | ||||
SEMA3D | Semaphorin-3D; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (761 aa) | ||||
KIAA1024 | DD1 protein. (916 aa) | ||||
RYK | Receptor like tyrosine kinase. (481 aa) | ||||
PLXNA4 | Plexin A4. (1892 aa) | ||||
PAK2 | Non-specific serine/threonine protein kinase. (521 aa) | ||||
CRKL | CRK like proto-oncogene, adaptor protein. (193 aa) | ||||
NEU4 | Neuraminidase 4. (449 aa) | ||||
PAFAH1B1 | Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration. (410 aa) | ||||
KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa) | ||||
NCKIPSD | NCK interacting protein with SH3 domain. (759 aa) | ||||
ARSI | Arylsulfatase family member I. (574 aa) | ||||
ULK2 | Unc-51 like autophagy activating kinase 2. (1001 aa) | ||||
CUX2 | Homeobox protein cut-like. (1386 aa) | ||||
TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (785 aa) | ||||
SEMA3G | Semaphorin 3G; Belongs to the semaphorin family. (761 aa) | ||||
NEDD4 | E3 ubiquitin-protein ligase. (932 aa) | ||||
MFSD2A | Major facilitator superfamily domain containing 2A. (528 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1111 aa) | ||||
DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (240 aa) | ||||
NTNG2 | Netrin G2. (527 aa) | ||||
SETX | Senataxin. (2801 aa) | ||||
SARM1 | Uncharacterized protein. (454 aa) | ||||
FN1 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). (2526 aa) | ||||
E1C066_CHICK | Uncharacterized protein. (258 aa) | ||||
OCM | Parvalbumin, thymic CPV3; Binds two calcium ions. (109 aa) | ||||
PRRX1 | Paired mesoderm homeobox protein 1; May participate in maintenance of mesenchymal cell lineages derived from both mesoderm and the neural crest and in patterning of the limbs and the face. (245 aa) | ||||
CRTC1 | CREB regulated transcription coactivator 1. (620 aa) | ||||
SEMA3DL | Ig-like domain-containing protein. (165 aa) | ||||
HOMER3 | Sema domain-containing protein; Belongs to the semaphorin family. (763 aa) | ||||
RND2 | Uncharacterized protein. (227 aa) | ||||
PACSIN1 | Protein kinase C and casein kinase substrate in neurons 1. (403 aa) | ||||
SEMA6A | Semaphorin-6A isoform4; Belongs to the semaphorin family. (1044 aa) | ||||
NPTN | Uncharacterized protein. (397 aa) | ||||
LRIG2 | Leucine rich repeats and immunoglobulin like domains 2. (1055 aa) | ||||
LZTS1 | Leucine zipper tumor suppressor 1. (604 aa) | ||||
SEMA7A | Sema domain-containing protein; Belongs to the semaphorin family. (636 aa) | ||||
PLXNA2 | Plexin A2. (1893 aa) | ||||
WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) | ||||
GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (422 aa) | ||||
SF3A2 | Splicing factor 3a subunit 2. (315 aa) | ||||
RAB29 | RAB29, member RAS oncogene family. (205 aa) | ||||
PAK1 | Non-specific serine/threonine protein kinase. (544 aa) | ||||
TANC2 | Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2. (2067 aa) | ||||
CHODL | Chondrolectin. (291 aa) | ||||
SEMA4D | Semaphorin-4D; Cell surface receptor for PLXNB1 that plays an important role in cell-cell signaling (By similarity). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (By similarity). (855 aa) | ||||
EPHB3 | Ephrin type-B receptor 3; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development. In addition to its role in axon guidance plays also an important re [...] (971 aa) | ||||
FRMD7 | FERM domain containing 7. (686 aa) | ||||
NTN1 | Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors. (688 aa) | ||||
NELL2 | Protein NEL. (816 aa) | ||||
ARSB | Arylsulfatase B. (514 aa) |