(26 nodes) ER to Golgi transport vesicle membrane network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SEC24C	Uncharacterized protein. (1142 aa)
	KLHL12	Kelch like family member 12. (565 aa)
	SEC16A	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2201 aa)
	SAR1A	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	SEC24A	Uncharacterized protein. (1100 aa)
	SEC23B	Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
	VMA21	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. (102 aa)
	VTI1B	Vesicle transport through interaction with t-SNAREs 1B. (232 aa)
	PDCD6	Programmed cell death 6. (178 aa)
	SREBF1	BHLH domain-containing protein. (1116 aa)
	SEC23A	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	PEF1	Penta-EF-hand domain containing 1. (223 aa)
	SEC16B	Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes. (1084 aa)
	SEC24B	Uncharacterized protein. (1234 aa)
	SEC22B	Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. (215 aa)
	SAR1B	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	USO1	Uncharacterized protein. (963 aa)
	SREBF2	Sterol regulatory element binding transcription factor 2. (1112 aa)
	VTI1A	t-SNARE coiled-coil homology domain-containing protein. (224 aa)
	SEC13	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (579 aa)
	SEC31B	SEC31 homolog B, COPII coat complex component. (1217 aa)
	GOSR2	Uncharacterized protein. (333 aa)
	SCAP	SREBF chaperone. (1316 aa)
	SEC31A	Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1284 aa)
	SEC24D	SEC24 homolog D, COPII coat complex component. (1073 aa)
	STX17	t-SNARE coiled-coil homology domain-containing protein. (302 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GOSR2	SAR1B	ENSGALP00000068961	ENSGALP00000055599	Uncharacterized protein.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.592
GOSR2	SEC13	ENSGALP00000068961	ENSGALP00000060372	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.668
GOSR2	SEC16A	ENSGALP00000068961	ENSGALP00000003718	Uncharacterized protein.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.595
GOSR2	SEC16B	ENSGALP00000068961	ENSGALP00000048637	Uncharacterized protein.	Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes.	0.593
GOSR2	SEC22B	ENSGALP00000068961	ENSGALP00000051201	Uncharacterized protein.	Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.	0.998
GOSR2	SEC23A	ENSGALP00000068961	ENSGALP00000046119	Uncharacterized protein.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.671
GOSR2	SEC24A	ENSGALP00000068961	ENSGALP00000010342	Uncharacterized protein.	Uncharacterized protein.	0.634
GOSR2	SEC24B	ENSGALP00000068961	ENSGALP00000050553	Uncharacterized protein.	Uncharacterized protein.	0.644
GOSR2	SEC24C	ENSGALP00000068961	ENSGALP00000073540	Uncharacterized protein.	Uncharacterized protein.	0.627
GOSR2	SEC24D	ENSGALP00000068961	ENSGALP00000072248	Uncharacterized protein.	SEC24 homolog D, COPII coat complex component.	0.640
GOSR2	SEC31A	ENSGALP00000068961	ENSGALP00000070610	Uncharacterized protein.	Protein transport protein Sec31A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).	0.559
GOSR2	STX17	ENSGALP00000068961	ENSGALP00000074169	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.711
GOSR2	USO1	ENSGALP00000068961	ENSGALP00000055676	Uncharacterized protein.	Uncharacterized protein.	0.995
GOSR2	VTI1A	ENSGALP00000068961	ENSGALP00000059444	Uncharacterized protein.	t-SNARE coiled-coil homology domain-containing protein.	0.844
GOSR2	VTI1B	ENSGALP00000068961	ENSGALP00000015493	Uncharacterized protein.	Vesicle transport through interaction with t-SNAREs 1B.	0.794
KLHL12	PEF1	ENSGALP00000000711	ENSGALP00000047759	Kelch like family member 12.	Penta-EF-hand domain containing 1.	0.932
KLHL12	SAR1A	ENSGALP00000000711	ENSGALP00000007043	Kelch like family member 12.	Secretion associated Ras related GTPase 1A; Belongs to the small GTPase superfamily. SAR1 family.	0.475
KLHL12	SAR1B	ENSGALP00000000711	ENSGALP00000055599	Kelch like family member 12.	Uncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family.	0.583
KLHL12	SEC13	ENSGALP00000000711	ENSGALP00000060372	Kelch like family member 12.	WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family.	0.622
KLHL12	SEC16A	ENSGALP00000000711	ENSGALP00000003718	Kelch like family member 12.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.779