STRINGSTRING
LOC776719 LOC776719 CD44 CD44 SLC19A1 SLC19A1 IL6R IL6R SLC4A11 SLC4A11 SLC2A13 SLC2A13 PSEN2 PSEN2 ENSGALP00000059634 ENSGALP00000059634 RAB18 RAB18 P2RX2 P2RX2 VSIG10L VSIG10L STXBP3 STXBP3 SHROOM1 SHROOM1 CIB3 CIB3 SLC26A4 SLC26A4 SCNN1D SCNN1D ENSGALP00000065672 ENSGALP00000065672 MPDZ MPDZ SLC6A6 SLC6A6 PARD3B PARD3B SLC9A3R1 SLC9A3R1 MYO1A MYO1A ENSGALP00000066589 ENSGALP00000066589 EMP2 EMP2 DLL1 DLL1 C20orf27 C20orf27 SHROOM3 SHROOM3 PKHD1 PKHD1 ENSGALP00000067896 ENSGALP00000067896 ENSGALP00000068033 ENSGALP00000068033 AKAP7 AKAP7 LOC107049680 LOC107049680 CD36 CD36 CFAP126 CFAP126 HAX1 HAX1 PSEN1 PSEN1 ENSGALP00000069823 ENSGALP00000069823 ENSGALP00000070136 ENSGALP00000070136 ATP6V1A ATP6V1A ADCY10L11 ADCY10L11 PROM1L PROM1L ENSGALP00000071132 ENSGALP00000071132 ITPK1 ITPK1 SLC9A1 SLC9A1 KCNQ1 KCNQ1 PODXL PODXL LOC112530976 LOC112530976 SLC23A2 SLC23A2 FZD6 FZD6 TEK TEK ENSGALP00000072166 ENSGALP00000072166 SORBS2 SORBS2 SLC4A7 SLC4A7 UMODL1 UMODL1 FAT1 FAT1 CLDN7 CLDN7 GJA1 GJA1 ENSGALP00000074194 ENSGALP00000074194 DSTYK DSTYK SLC39A14 SLC39A14 F1NA95_CHICK F1NA95_CHICK SLC12A1 SLC12A1 AQP1 AQP1 SLC9A3R2 SLC9A3R2 STK26 STK26 SCNN1B SCNN1B SLC22A18 SLC22A18 ATP12A ATP12A RHCG RHCG C1QTNF5 C1QTNF5 E1C7P2_CHICK E1C7P2_CHICK ATP6V1G1 ATP6V1G1 ABCC2 ABCC2 MYO1B MYO1B PARD6B PARD6B ADAM17 ADAM17 SLC26A3 SLC26A3 SLC7A1 SLC7A1 LMO7 LMO7 ATP4B ATP4B GPR143 GPR143 LOC421965 LOC421965 TMEM30A TMEM30A CDH2 CDH2 UPK1B UPK1B F1NFV7_CHICK F1NFV7_CHICK SLC1A1 SLC1A1 AKR1A1 AKR1A1 SLC29A4 SLC29A4 KCNK1 KCNK1 AMN AMN SLC39A8 SLC39A8 CTSV CTSV SLC6A18 SLC6A18 SLC6A19 SLC6A19 SLC5A12 SLC5A12 PARD6G PARD6G EZR EZR UPK3A UPK3A SLC34A2 SLC34A2 PROM1 PROM1 CIB4 CIB4 CPO CPO DDR1 DDR1 CUBN CUBN JAG1 JAG1 MPP5 MPP5 USH2A USH2A KCNK2 KCNK2 ABCG5 ABCG5 ABCG8 ABCG8 SLC3A1 SLC3A1 AQP5 AQP5 AQP2 AQP2 MIP MIP ENPEP ENPEP KCNE4 KCNE4 CYBRD1 CYBRD1 CFTR CFTR DDR2 DDR2 RAB18L RAB18L SHANK2 SHANK2 DRAM2 DRAM2 ECRG4 ECRG4 HIP1R HIP1R RAPGEF2 RAPGEF2 PARD3 PARD3 SLC6A20 SLC6A20 ATP6V0D2 ATP6V0D2 SLC22A4 SLC22A4 ZMYND10 ZMYND10 DPP4 DPP4 TMEM114 TMEM114 DUOX2 DUOX2 SLC7A5 SLC7A5 ENSGALP00000054145 ENSGALP00000054145 ABCG2 ABCG2 ABCC5 ABCC5 ADCY8 ADCY8 SLC7A9 SLC7A9 KIAA1614 KIAA1614 MREG MREG OSMR OSMR SLC46A1 SLC46A1 ITGB3 ITGB3 FN1 FN1 NOTCH1 NOTCH1 PRKCZ PRKCZ PARD6A PARD6A CD34 CD34 SLC26A9 SLC26A9 ATP6V1B2 ATP6V1B2 PROM2 PROM2 SLC22A5 SLC22A5 SLC23A1 SLC23A1 SHROOM2 SHROOM2 MAL2 MAL2 RAPGEF6 RAPGEF6 OTOA OTOA AJAP1 AJAP1 SCNN1G SCNN1G CLDND1 CLDND1 SLC2A1 SLC2A1 CDH15 CDH15 SCNN1A SCNN1A SHROOM4 SHROOM4 EXOC1 EXOC1 CTSK CTSK PATJ PATJ PLPP1 PLPP1 MSN MSN SLC4A10 SLC4A10 FAM65B FAM65B SLC34A1 SLC34A1 PDGFRB PDGFRB FZD3 FZD3 CLDN1 CLDN1 MARVELD2 MARVELD2 SLC26A6 SLC26A6 PDZD3 PDZD3 LOC422308 LOC422308 PRKCI PRKCI CRB2 CRB2 F2RL2 F2RL2 SLC12A2 SLC12A2 PTPRO PTPRO ANXA1 ANXA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC776719Uncharacterized protein. (671 aa)
CD44Link domain-containing protein. (696 aa)
SLC19A1Uncharacterized protein. (496 aa)
IL6RUncharacterized protein. (445 aa)
SLC4A11Solute carrier family 4 member 11. (867 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (620 aa)
PSEN2Presenilin-2 CTF subunit; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the other members of the gamma- secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. The holoprotein functions as a calcium-leak channel that allows the passive movement o [...] (455 aa)
ENSGALP00000059634Uncharacterized protein. (221 aa)
RAB18Ras-related protein Rab-18; Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration (By similarity). (206 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (507 aa)
VSIG10LIg-like domain-containing protein. (433 aa)
STXBP3Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (601 aa)
SHROOM1Uncharacterized protein. (1313 aa)
CIB3Calcium and integrin binding family member 3. (185 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (816 aa)
SCNN1DSodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
ENSGALP00000065672Uncharacterized protein. (283 aa)
MPDZUncharacterized protein. (2106 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (708 aa)
PARD3BPar-3 family cell polarity regulator beta. (1201 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. May enhance Wnt signaling (By similarity). (366 aa)
MYO1AUnconventional myosin-Ia; Could play an important role in morphogenesis and function of intestinal microvilli; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1257 aa)
ENSGALP00000066589Uncharacterized protein. (349 aa)
EMP2Epithelial membrane protein 2. (167 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (893 aa)
C20orf27Calponin-homology (CH) domain-containing protein. (740 aa)
SHROOM3Shroom family member 3. (1997 aa)
PKHD1Uncharacterized protein. (551 aa)
ENSGALP00000067896Uncharacterized protein. (105 aa)
ENSGALP00000068033Uncharacterized protein. (527 aa)
AKAP7A-kinase anchoring protein 7. (468 aa)
LOC107049680ATP-synt_ab domain-containing protein. (721 aa)
CD36Uncharacterized protein; Belongs to the CD36 family. (471 aa)
CFAP126Cilia and flagella associated protein 126. (195 aa)
HAX1HCLS1 associated protein X-1. (315 aa)
PSEN1Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa)
ENSGALP00000069823Uncharacterized protein. (167 aa)
ENSGALP00000070136Uncharacterized protein. (121 aa)
ATP6V1AV-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity. Belongs to the ATPase alpha/beta chains family. (617 aa)
ADCY10L11Uncharacterized protein. (298 aa)
PROM1LUncharacterized protein. (788 aa)
ENSGALP00000071132Uncharacterized protein. (386 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway. May also act as an isomerase that interconverts the inositol tetrakisphos [...] (455 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (850 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (863 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubul [...] (589 aa)
LOC112530976FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (77 aa)
SLC23A2Sodium vitamin C co-transporter 2. (658 aa)
FZD6Frizzled-6; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (709 aa)
TEKTEK receptor tyrosine kinase. (1128 aa)
ENSGALP00000072166IPT/TIG domain-containing protein. (239 aa)
SORBS2Sorbin and SH3 domain containing 2. (1206 aa)
SLC4A7Anion exchange protein. (1243 aa)
UMODL1Uncharacterized protein. (780 aa)
FAT1FAT atypical cadherin 1. (4645 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (407 aa)
GJA1Gap junction alpha-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Plays an essential role in gap junction communication in the ventricles. Belongs to the connexin family. Alpha-type (group II) subfamily. (381 aa)
ENSGALP00000074194Uncharacterized protein. (401 aa)
DSTYKDual serine/threonine and tyrosine protein kinase; May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (930 aa)
SLC39A14Solute carrier family 39 member 14. (508 aa)
F1NA95_CHICKAKAP7_NLS domain-containing protein. (256 aa)
SLC12A1Solute carrier family 12 member 1. (1097 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (354 aa)
STK26Protein kinase domain-containing protein. (416 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (667 aa)
SLC22A18Solute carrier family 22 member 18. (427 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1033 aa)
RHCGAmmonium transporter Rh type C; Functions as an ammonia transporter. (467 aa)
C1QTNF5C1q and TNF related 5. (585 aa)
E1C7P2_CHICKUncharacterized protein. (264 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
ABCC2Uncharacterized protein. (1538 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1112 aa)
PARD6BPAR6B. (370 aa)
ADAM17Tumor necrosis factor alpha converting enzyme. (829 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (754 aa)
SLC7A1AA_permease_C domain-containing protein. (624 aa)
LMO7LIM domain 7. (1608 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (299 aa)
GPR143Uncharacterized protein. (391 aa)
LOC421965Uncharacterized protein. (556 aa)
TMEM30ACell cycle control protein 50A; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate. Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex. [...] (372 aa)
CDH2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). (912 aa)
UPK1BTetraspanin. (283 aa)
F1NFV7_CHICKUncharacterized protein. (1145 aa)
SLC1A1Amino acid transporter. (527 aa)
AKR1A1Aldo-keto reductase family 1 member A1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity). (365 aa)
SLC29A4Solute carrier family 29 member 4. (527 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
AMNUncharacterized protein. (477 aa)
SLC39A8Solute carrier family 39 member 8. (493 aa)
CTSVCathepsin L1 heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. (353 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (619 aa)
SLC6A19Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (636 aa)
SLC5A12Solute carrier family 5 member 12; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (629 aa)
PARD6GPar-6 family cell polarity regulator gamma. (384 aa)
EZREzrin. (585 aa)
UPK3AUroplakin 3A. (264 aa)
SLC34A2Uncharacterized protein. (673 aa)
PROM1Uncharacterized protein. (868 aa)
CIB4Uncharacterized protein. (190 aa)
CPOCarboxypeptidase O. (379 aa)
DDR1Uncharacterized protein. (873 aa)
CUBNCubilin. (3634 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)
MPP5Uncharacterized protein; Belongs to the MAGUK family. (675 aa)
USH2AUsherin. (5190 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (411 aa)
ABCG5ATP binding cassette subfamily G member 5. (630 aa)
ABCG8ATP binding cassette subfamily G member 8. (645 aa)
SLC3A1Solute carrier family 3 member 1. (678 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
AQP2Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (275 aa)
MIPLens fiber major intrinsic protein; Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
ENPEPAminopeptidase. (943 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (161 aa)
CYBRD1Cytochrome b reductase 1. (289 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (901 aa)
RAB18LUncharacterized protein. (204 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1462 aa)
DRAM2DNA damage regulated autophagy modulator 2. (266 aa)
ECRG4ECRG4 augurin precursor. (112 aa)
HIP1RUncharacterized protein. (977 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1652 aa)
PARD3Uncharacterized protein. (1352 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (647 aa)
ATP6V0D2V-type proton ATPase subunit d 2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity); Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
SLC22A4MFS domain-containing protein. (553 aa)
ZMYND10Zinc finger MYND-type containing 10. (405 aa)
DPP4Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa)
TMEM114Transmembrane protein 114. (211 aa)
DUOX2Dual oxidase 2. (1533 aa)
SLC7A5Large neutral amino acids transporter small subunit 1. (526 aa)
ENSGALP00000054145Uncharacterized protein. (217 aa)
ABCG2ATP-binding cassette sub-family G member 2. (701 aa)
ABCC5ATP binding cassette subfamily C member 5. (1449 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
SLC7A9Uncharacterized protein. (493 aa)
KIAA1614DUF4685 domain-containing protein. (752 aa)
MREGMelanoregulin. (208 aa)
OSMRUncharacterized protein. (622 aa)
SLC46A1Uncharacterized protein. (473 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (781 aa)
FN1Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). (2526 aa)
NOTCH1Uncharacterized protein. (2561 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
PARD6APar-6 family cell polarity regulator alpha. (357 aa)
CD34CD34 molecule. (385 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (806 aa)
ATP6V1B2V-type proton ATPase subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells; Belongs to the ATPase alpha/beta chains family. (503 aa)
PROM2Prominin 2. (824 aa)
SLC22A5MFS domain-containing protein. (557 aa)
SLC23A1Solute carrier family 23 member 1. (557 aa)
SHROOM2Shroom family member 2. (1755 aa)
MAL2MARVEL domain-containing protein. (178 aa)
RAPGEF6Uncharacterized protein. (1585 aa)
OTOAUncharacterized protein. (524 aa)
AJAP1Adherens junctions associated protein 1. (266 aa)
SCNN1GSodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa)
CLDND1Uncharacterized protein. (251 aa)
SLC2A1Solute carrier family 2, facilitated glucose transporter member 1; Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. (490 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (792 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. (612 aa)
SHROOM4Shroom family member 4. (1224 aa)
EXOC1Exocyst complex component 1. (920 aa)
CTSKCathepsin K; Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). (334 aa)
PATJPATJ crumbs cell polarity complex component. (1891 aa)
PLPP1Phospholipid phosphatase 1. (284 aa)
MSNMoesin. (580 aa)
SLC4A10Anion exchange protein. (1116 aa)
FAM65BRho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Requ [...] (1067 aa)
SLC34A1Solute carrier family 34 member 1. (675 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1073 aa)
FZD3Frizzled-3; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (666 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
MARVELD2MARVEL domain containing 2. (506 aa)
SLC26A6STAS domain-containing protein. (752 aa)
PDZD3PDZ domain containing 3. (531 aa)
LOC422308Sec3-PIP2_bind domain-containing protein. (860 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
CRB2Uncharacterized protein. (1469 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (378 aa)
SLC12A2Solute carrier family 12 member 2. (1150 aa)
PTPROUncharacterized protein. (1268 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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