35 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CYP2AB1	Uncharacterized protein; Belongs to the cytochrome P450 family. (489 aa)
	CYP2J19	Uncharacterized protein; Belongs to the cytochrome P450 family. (490 aa)
	CYP2D6	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family. (502 aa)
	CYP2AC1	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	HMOX1	Heme oxygenase 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. (317 aa)
	CYP1A1	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
	CYP2C23a	Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (491 aa)
	CYP2U1	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (524 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (536 aa)
	RP11-400G3.5	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	CYP7A1	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa)
	CYP1C1	Uncharacterized protein; Belongs to the cytochrome P450 family. (516 aa)
	LOC101749846	Uncharacterized protein; Belongs to the cytochrome P450 family. (668 aa)
	CYP2J21	Uncharacterized protein; Belongs to the cytochrome P450 family. (558 aa)
	CYP2W1	Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (505 aa)
	CYP2J22	Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
	CYP2AC7	Uncharacterized protein; Belongs to the cytochrome P450 family. (501 aa)
	CYP2J23	Uncharacterized protein; Belongs to the cytochrome P450 family. (491 aa)
	CYP2AC2	Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
	CYP2AB3	Uncharacterized protein; Belongs to the cytochrome P450 family. (488 aa)
	LOC112530469	Uncharacterized protein. (846 aa)
	CYP19A1	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (502 aa)
	ENSGALP00000068450	Uncharacterized protein. (96 aa)
	CYP1A2	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (530 aa)
	TTI2	TELO2 interacting protein 2. (471 aa)
	CYP2W1-2	Uncharacterized protein; Belongs to the cytochrome P450 family. (500 aa)
	CYP3A4	Uncharacterized protein; Belongs to the cytochrome P450 family. (540 aa)
	CYP3A5	Uncharacterized protein. (508 aa)
	CYP2C18	Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
	CYP2C23b	Cytochrome P450 2H2; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (491 aa)
	CYP2R1	Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (646 aa)
	HMOX2	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (313 aa)
	CYP2AB5	Uncharacterized protein. (831 aa)
	CYP2AB2	Uncharacterized protein; Belongs to the cytochrome P450 family. (488 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (486 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP19A1	CYP1A1	ENSGALP00000066452	ENSGALP00000039219	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.949
CYP19A1	CYP1A2	ENSGALP00000066452	ENSGALP00000002016	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.946
CYP19A1	CYP1B1	ENSGALP00000066452	ENSGALP00000048510	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.628
CYP19A1	CYP1C1	ENSGALP00000066452	ENSGALP00000055162	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.529
CYP19A1	CYP2J19	ENSGALP00000066452	ENSGALP00000018598	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.403
CYP19A1	CYP2U1	ENSGALP00000066452	ENSGALP00000041133	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.417
CYP19A1	CYP3A4	ENSGALP00000066452	ENSGALP00000007048	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.943
CYP19A1	CYP3A5	ENSGALP00000066452	ENSGALP00000007068	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Uncharacterized protein.	0.943
CYP19A1	CYP7A1	ENSGALP00000066452	ENSGALP00000054104	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.	0.684
CYP1A1	CYP19A1	ENSGALP00000039219	ENSGALP00000066452	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.949
CYP1A1	CYP1A2	ENSGALP00000039219	ENSGALP00000002016	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 1A5; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.958
CYP1A1	CYP1B1	ENSGALP00000039219	ENSGALP00000048510	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.932
CYP1A1	CYP2AC1	ENSGALP00000039219	ENSGALP00000026886	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.407
CYP1A1	CYP2C18	ENSGALP00000039219	ENSGALP00000008773	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.924
CYP1A1	CYP2C23a	ENSGALP00000039219	ENSGALP00000039271	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 2H1; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.478
CYP1A1	CYP2C23b	ENSGALP00000039219	ENSGALP00000009294	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 2H2; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.562
CYP1A1	CYP2D6	ENSGALP00000039219	ENSGALP00000019386	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 CYP2D49; Belongs to the cytochrome P450 family.	0.560
CYP1A1	CYP2U1	ENSGALP00000039219	ENSGALP00000041133	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.557
CYP1A1	CYP3A4	ENSGALP00000039219	ENSGALP00000007048	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.960
CYP1A1	CYP3A5	ENSGALP00000039219	ENSGALP00000007068	Cytochrome P450 1A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Uncharacterized protein.	0.970