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| | SLC45A3 | Solute carrier family 45 member 3. (569 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (262 aa) |
| | DM5L | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) |
| | BBS4 | TPR_REGION domain-containing protein. (532 aa) |
| | STOML2 | Stomatin like 2. (382 aa) |
| | SEC14L5 | SEC14 like lipid binding 5. (710 aa) |
| | DGKQ | Diacylglycerol kinase. (904 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (790 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (881 aa) |
| | BRCA1 | Uncharacterized protein. (1749 aa) |
| | ERLIN2 | ER lipid raft associated 2. (342 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity). (281 aa) |
| | ERLIN1 | PHB domain-containing protein. (347 aa) |
| | MTOR | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2521 aa) |
| | LACTB | Uncharacterized protein. (520 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (528 aa) |
| | PRMT3 | Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (526 aa) |
| | GPER1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | DISP3 | Protein dispatched homolog 3; Plays a role in neuronal proliferation and differentiation (By similarity). Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells. (1338 aa) |
| | EPHA8 | EPH receptor A8. (1002 aa) |
| | E1BT64_CHICK | Uncharacterized protein. (206 aa) |
| | SAMD8 | Sterile alpha motif domain containing 8. (415 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (713 aa) |
| | TTC39B | Tetratricopeptide repeat domain 39B. (554 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (501 aa) |
| | ADIPOQ | C1q domain-containing protein. (244 aa) |
| | ABHD6 | Abhydrolase domain containing 6. (338 aa) |
| | PIK3IP1 | Phosphoinositide-3-kinase interacting protein 1. (255 aa) |
| | APOD | Apolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa) |
| | APOA1 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. (264 aa) |
| | DAGLB | Lipase_3 domain-containing protein. (667 aa) |
| | RUBCN | Rubicon autophagy regulator. (904 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate; Belongs to the phosphoenolpyruvate carboxykinase [...] (622 aa) |
| | EGR1 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (510 aa) |
| | HTR2B | Serotonin receptor subtype 2b. (462 aa) |
| | SNAI1 | Snail like protein. (256 aa) |
| | MTMR3 | Uncharacterized protein. (1257 aa) |
| | F2 | Uncharacterized protein; Belongs to the peptidase S1 family. (644 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | CREB1 | cAMP response element-binding protein. (327 aa) |
| | CYR61 | CCN family member 1; Probable secreted regulatory protein. (375 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (415 aa) |
| | DNAJC19 | DnaJ heat shock protein family (Hsp40) member C19. (115 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (728 aa) |
| | PDK4 | Protein-serine/threonine kinase. (414 aa) |
| | TTC39A | Tetratricopeptide repeat domain 39A. (576 aa) |
| | NR1H4 | Farnesoid X receptor. (473 aa) |
| | FMC1 | Formation of mitochondrial complex V assembly factor 1 homolog. (247 aa) |
| | ATG14 | Autophagy related 14. (492 aa) |
| | PDGFB | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (251 aa) |
| | PLA2G6 | Uncharacterized protein. (796 aa) |
| | GOLM1 | Golgi membrane protein 1. (376 aa) |
| | BMP6 | Bone morphogenetic protein 6. (434 aa) |
| | PDK1 | Protein-serine/threonine kinase; Belongs to the PDK/BCKDK protein kinase family. (408 aa) |
| | ENPP7 | Ectonucleotide pyrophosphatase/phosphodiesterase 7. (444 aa) |
| | PNPLA2 | PNPLA2/ATGL. (483 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (560 aa) |
| | ZBTB20 | Zinc finger and BTB domain containing 20. (669 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (803 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (666 aa) |
| | NR0B1 | NR LBD domain-containing protein. (263 aa) |
| | PDK3 | Protein-serine/threonine kinase. (406 aa) |
| | EPHX2 | AB hydrolase-1 domain-containing protein. (596 aa) |
| | MTMR9 | Myotubularin phosphatase domain-containing protein. (550 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (761 aa) |
| | DNAJC15 | J domain-containing protein. (148 aa) |
| | RUBCNL | Rubicon like autophagy enhancer. (656 aa) |
| | HTR2A | 5-hydroxytryptamine (Serotonin) receptor 2A. (468 aa) |
| | NR1D2 | Uncharacterized protein. (587 aa) |
| | ARV1 | ARV1 homolog, fatty acid homeostasis modulator. (234 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (872 aa) |
| | SOX9 | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] (494 aa) |
| | DDX20 | DEAD-box helicase 20; Belongs to the DEAD box helicase family. (767 aa) |
| | ASAH1 | Uncharacterized protein; Belongs to the acid ceramidase family. (395 aa) |
| | ORMDL3 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa) |
| | TM6SF2 | Transmembrane 6 superfamily member 2. (349 aa) |
| | SREBF1 | BHLH domain-containing protein. (1116 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (671 aa) |
| | ETFBKMT | Uncharacterized protein. (263 aa) |
| | CCL19-2 | SCY domain-containing protein. (99 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa) |
| | CAV1 | Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa) |
| | FGR | Proto-oncogene tyrosine-protein kinase Yrk; May participate in signaling pathways; Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (536 aa) |
| | PDGFRB | Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1073 aa) |
| | SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (347 aa) |
| | ABCG4 | ATP binding cassette subfamily G member 4. (685 aa) |
| | SPHK1 | Sphingosine kinase 1. (649 aa) |
| | WNT4 | Protein Wnt-4; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development (By similarity). (351 aa) |
| | LYN | Tyrosine-protein kinase. (491 aa) |
| | MLXIPL | BHLH domain-containing protein. (895 aa) |
| | MID1IP1 | THRSP-like protein. (159 aa) |
| | TYSND1 | Trypsin domain containing 1. (493 aa) |
| | LPGAT1 | PlsC domain-containing protein. (400 aa) |
| | RORC | RAR related orphan receptor C. (461 aa) |
| | PSAP | Prosaposin; The lysosomal degradation of sphingolipids takes place by the sequential action of specific hydrolases. Some of these enzymes require specific low-molecular mass, non-enzymic proteins: the sphingolipids activator proteins (coproteins). Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta- galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha- galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. (538 aa) |
| | IL1B | Interleukin-1; Belongs to the IL-1 family. (267 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1426 aa) |
| | FMO5 | Flavin-containing monooxygenase. (277 aa) |
| | ABCD2 | Uncharacterized protein. (730 aa) |
| | PRRC2C-2 | Flavin-containing monooxygenase. (126 aa) |
| | PPARA | Uncharacterized protein. (468 aa) |
| | FMO3 | Dimethylaniline monooxygenase [N-oxide-forming]. (530 aa) |
| | ABHD4 | AB hydrolase-1 domain-containing protein. (385 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa) |
| | FABP5 | FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (291 aa) |
| | THRSP | Thyroid hormone responsive spot 14 alpha 2. (129 aa) |
| | CCDC3 | Coiled-coil domain containing 3. (325 aa) |
| | RARRES2 | Chemerin. (162 aa) |
| | SNAI2 | Uncharacterized protein. (258 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (884 aa) |
| | SREBF2 | Sterol regulatory element binding transcription factor 2. (1112 aa) |
| | CREBL2 | BZIP domain-containing protein. (120 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa) |
| | PDK2 | Protein-serine/threonine kinase. (412 aa) |
| | LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (501 aa) |
| | CNEP1R1 | Uncharacterized protein. (174 aa) |
| | SIRT6 | Deacetylase sirtuin-type domain-containing protein. (378 aa) |
| | CD74 | Invariant chain isoform p41. (286 aa) |
| | ANGPTL3 | Fibrinogen C-terminal domain-containing protein. (464 aa) |
| | ORMDL2 | ORM1-like protein 2; Negative regulator of sphingolipid synthesis; Belongs to the ORM family. (153 aa) |
| | LPIN1 | Lipin 1. (1003 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (503 aa) |
| | CDC42 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...] (194 aa) |
| | GIP | GLUCAGON domain-containing protein. (139 aa) |
| | SLC27A1 | AMP-binding domain-containing protein. (719 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | REST | Uncharacterized protein. (339 aa) |
| | ENSGALP00000067656 | Uncharacterized protein. (174 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (498 aa) |
| | CCL19 | C-C motif chemokine. (108 aa) |
| | ENSGALP00000068754 | Uncharacterized protein. (89 aa) |
| | MTMR9LP | Myotubularin phosphatase domain-containing protein. (574 aa) |
| | ARMC5 | Uncharacterized protein. (535 aa) |
| | PNPLA3 | Patatin like phospholipase domain containing 3. (543 aa) |
| | STARD4 | START domain-containing protein. (224 aa) |
| | MTMR4 | Myotubularin related protein 4. (1221 aa) |
| | PODN | Podocan. (632 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (678 aa) |
| | FGF1 | Endothelial cell growth factor alpha; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with [...] (155 aa) |
| | SCAP | SREBF chaperone. (1316 aa) |
| | ORMDL1 | ORM1-like protein; Negative regulator of sphingolipid synthesis. (161 aa) |
| | CGA | Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (120 aa) |
| | OPA3 | Outer mitochondrial membrane lipid metabolism regulator OPA3. (169 aa) |
| | CTDNEP1 | Uncharacterized protein. (179 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (856 aa) |
| | THRSPB | Uncharacterized protein. (174 aa) |
| | SIRT4 | Sirtuin 4. (332 aa) |
| | RORA | Uncharacterized protein. (524 aa) |
| | TEK | TEK receptor tyrosine kinase. (1128 aa) |
| | DAB2 | DAB adaptor protein 2. (715 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (856 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (697 aa) |
| | PPARD | Uncharacterized protein. (545 aa) |
| | FITM2 | Fat storage inducing transmembrane protein 2. (396 aa) |
| | TNFAIP8L3 | TNF alpha induced protein 8 like 3. (204 aa) |
| | NR1H3 | Uncharacterized protein. (519 aa) |
| | ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1342 aa) |
| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (484 aa) |
