STRINGSTRING
LRRC1 LRRC1 FUT9 FUT9 K4LB56_CHICK K4LB56_CHICK KIFAP3 KIFAP3 RASGRP1 RASGRP1 LOC101748499 LOC101748499 DMB2 DMB2 EFNA5 EFNA5 NDFIP1 NDFIP1 PLA2G2A PLA2G2A SASH3 SASH3 HLX HLX TESPA1 TESPA1 PCASP2 PCASP2 PAG1 PAG1 CD5 CD5 SMAD7B SMAD7B LOC771545 LOC771545 PTPRC PTPRC ITCH ITCH SMAD7 SMAD7 BLB1 BLB1 MEGF10 MEGF10 IL2RG IL2RG ITGA4 ITGA4 IL4R IL4R TYK2 TYK2 PCASP3 PCASP3 PPARA PPARA DPP4 DPP4 ABL2 ABL2 DUSP3 DUSP3 IL7 IL7 BLB2 BLB2 CXCL13L3 CXCL13L3 IL1B IL1B DLG5 DLG5 AFDN AFDN ZNF703 ZNF703 IGF2 IGF2 ZBTB32 ZBTB32 UBASH3B UBASH3B CCR7 CCR7 C6H10orf54 C6H10orf54 CDH15 CDH15 MYB MYB ZC3H12A ZC3H12A LYN LYN RIPK2 RIPK2 MALT1 MALT1 ENSGALP00000046379 ENSGALP00000046379 BLB3 BLB3 DENND6A DENND6A FAM65B FAM65B CG-16 CG-16 CHST2 CHST2 ADTRP ADTRP CAV1 CAV1 CD24 CD24 NFAT5 NFAT5 CX3CL1 CX3CL1 ZDHHC21 ZDHHC21 TNFSF11 TNFSF11 DMB1 DMB1 THY1 THY1 B2M B2M EPHB3 EPHB3 PELI3 PELI3 TPPNR1L TPPNR1L SOX9 SOX9 AMBRA1 AMBRA1 ZBTB1 ZBTB1 CD86 CD86 FLOT2 FLOT2 ENSGALP00000063099 ENSGALP00000063099 SOCS6 SOCS6 PRKAR1A PRKAR1A LOC101751887 LOC101751887 NF2 NF2 ANXA1 ANXA1 TNFRSF13C TNFRSF13C CD47 CD47 CD9 CD9 RPS3 RPS3 SLC7A1 SLC7A1 RGCC RGCC TNFSF13B TNFSF13B TNFRSF21 TNFRSF21 BLK BLK MFSD2B MFSD2B EPHA7 EPHA7 CD80 CD80 NFKBIZ NFKBIZ SYK SYK CDH2 CDH2 CD274 CD274 VTCN1 VTCN1 IL6ST IL6ST PTPN2 PTPN2 CDH7 CDH7 IL7R IL7R IL20RB IL20RB BMP6 BMP6 CG-1B CG-1B AMHR2 AMHR2 IL21 IL21 IGFBP2 IGFBP2 TGFBR2 TGFBR2 IHH IHH IL12RB2 IL12RB2 MYO10L MYO10L JAK1 JAK1 GPNMB GPNMB PLPP3 PLPP3 KIF26B KIF26B MMRN1 MMRN1 CXCL13L2 CXCL13L2 PAWR PAWR DOCK8 DOCK8 SOCS5 SOCS5 FUT4 FUT4 IL12A IL12A ARG2 ARG2 DUSP10 DUSP10 FGG FGG TMEM131L TMEM131L JAG1 JAG1 CD74 CD74 SIRPA SIRPA CD83 CD83 VSIG4 VSIG4 VPS33B VPS33B CXCL13 CXCL13 NRARP NRARP MARCHF7 MARCHF7 GPAM GPAM CD28 CD28 CTLA4 CTLA4 CAV3 CAV3 FGL2 FGL2 HSPD1 HSPD1 CEBPB CEBPB MAP2K5 MAP2K5 NEXMIF NEXMIF PCK1 PCK1 FADD FADD TFRC TFRC SOCS1 SOCS1 APOA1 APOA1 LOC771388 LOC771388 GTPBP4 GTPBP4 CD81 CD81 CRTAM CRTAM GLMN GLMN XBP1 XBP1 ADIPOQ ADIPOQ SERPINE2 SERPINE2 SH2B3 SH2B3 LOC107052104 LOC107052104 CARD11 CARD11 MAD1L1 MAD1L1 ABL1 ABL1 ADAM19 ADAM19 CBFB CBFB DEF6 DEF6 PRKCD PRKCD CD276 CD276 ZAP70 ZAP70 IL12B IL12B RC3H2 RC3H2 CHST4 CHST4 IL10 IL10 LRRC32 LRRC32 SOX13 SOX13 LCK LCK DMA DMA LOC112531223 LOC112531223 FAM49B FAM49B TSPAN32 TSPAN32 DMTN DMTN ENSGALP00000065981 ENSGALP00000065981 ENSGALP00000066004 ENSGALP00000066004 IL12RB1 IL12RB1 ENSGALP00000066325 ENSGALP00000066325 BLA BLA ST3GAL4 ST3GAL4 HHLA2 HHLA2 NCK1 NCK1 EFNB2 EFNB2 IL6 IL6 CCL19 CCL19 TRAF6 TRAF6 ENSGALP00000068651 ENSGALP00000068651 GATA3 GATA3 FGL1 FGL1 IL15 IL15 LOC101750889 LOC101750889 AKNA AKNA RC3H1 RC3H1 MAGI1 MAGI1 TBX21 TBX21 PDCD1LG2 PDCD1LG2 CD6 CD6 RIPK3 RIPK3 ENSGALP00000071642 ENSGALP00000071642 PODXL PODXL NF2L NF2L SKAP1 SKAP1 ENSGALP00000072274 ENSGALP00000072274 LOC107057103 LOC107057103 FSTL3 FSTL3 FLOT1 FLOT1 PTPN6 PTPN6 RHOH RHOH DHPS DHPS LOC112531109 LOC112531109 EPB41L5 EPB41L5 ICOS ICOS ENSGALP00000073878 ENSGALP00000073878 CHIR-B2 CHIR-B2 LEF1 LEF1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LRRC1Leucine rich repeat containing 1. (797 aa)
FUT9CFUT9. (359 aa)
K4LB56_CHICKCD150. (333 aa)
KIFAP3Kinesin associated protein 3. (793 aa)
RASGRP1RAS guanyl releasing protein 1. (480 aa)
LOC101748499Ig-like domain-containing protein. (278 aa)
DMB2Ig-like domain-containing protein. (323 aa)
EFNA5Ephrin-A5; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor t [...] (223 aa)
NDFIP1Nedd4 family interacting protein 1. (213 aa)
PLA2G2APhospholipase A(2). (144 aa)
SASH3Uncharacterized protein. (382 aa)
HLXH2.0 like homeobox. (431 aa)
TESPA1KRAP_IP3R_bind domain-containing protein. (600 aa)
PCASP2Uncharacterized protein. (741 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (403 aa)
CD5Uncharacterized protein. (473 aa)
SMAD7BMothers against decapentaplegic homolog. (388 aa)
LOC771545Ig-like domain-containing protein. (262 aa)
PTPRCUncharacterized protein. (1237 aa)
ITCHE3 ubiquitin-protein ligase. (878 aa)
SMAD7Mothers against decapentaplegic homolog. (388 aa)
BLB1Ig-like domain-containing protein. (325 aa)
MEGF10Multiple EGF like domains 10. (1150 aa)
IL2RGFibronectin type-III domain-containing protein. (384 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1021 aa)
IL4RFibronectin type-III domain-containing protein. (996 aa)
TYK2Tyrosine-protein kinase. (1212 aa)
PCASP3Uncharacterized protein. (632 aa)
PPARAUncharacterized protein. (468 aa)
DPP4Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa)
ABL2Tyrosine-protein kinase. (1159 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa)
IL7Interleukin-7. (146 aa)
BLB2MHC class II beta chain 2. (263 aa)
CXCL13L3Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
IL1BInterleukin-1; Belongs to the IL-1 family. (267 aa)
DLG5Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1935 aa)
AFDNAfadin, adherens junction formation factor. (1912 aa)
ZNF703Zinc finger protein 703. (532 aa)
IGF2Insulin-like growth factor II; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for integrin which is required for IGF2 signaling. (187 aa)
ZBTB32Uncharacterized protein. (665 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (651 aa)
CCR7C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
C6H10orf54Ig-like domain-containing protein. (310 aa)
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (792 aa)
MYBTranscriptional activator Myb; Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. (785 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (681 aa)
LYNTyrosine-protein kinase. (491 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (574 aa)
MALT1MALT1 paracaspase. (816 aa)
ENSGALP00000046379Uncharacterized protein. (557 aa)
BLB3Class II histocompatibility antigen, B-L beta chain. (278 aa)
DENND6AProtein DENND6A; Guanine nucleotide exchange factor (GEF) for RAB14. Belongs to the DENND6 family. (584 aa)
FAM65BRho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Requ [...] (1067 aa)
CG-1616 kDa beta-galactoside-binding lectin; This protein binds beta-galactoside. Its physiological function is not yet known. It may be involved in the regulation of differentiation. (126 aa)
CHST2Sulfotransferase; Belongs to the sulfotransferase 1 family. (427 aa)
ADTRPAndrogen dependent TFPI regulating protein. (233 aa)
CAV1Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa)
CD24Uncharacterized protein. (87 aa)
NFAT5RHD domain-containing protein. (1520 aa)
CX3CL1SCY domain-containing protein. (496 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
TNFSF11TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (400 aa)
DMB1Ig-like domain-containing protein. (310 aa)
THY1Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. (161 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
EPHB3Ephrin type-B receptor 3; Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development. In addition to its role in axon guidance plays also an important re [...] (971 aa)
PELI3Uncharacterized protein. (418 aa)
TPPNR1LUncharacterized protein. (647 aa)
SOX9Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] (494 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (872 aa)
ZBTB1Zinc finger and BTB domain containing 1. (711 aa)
CD86Uncharacterized protein. (319 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
ENSGALP00000063099Uncharacterized protein. (330 aa)
SOCS6Suppressor of cytokine signaling 6. (534 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)
LOC101751887ANK_REP_REGION domain-containing protein. (178 aa)
NF2FERM domain-containing protein. (595 aa)
ANXA1Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa)
TNFRSF13CBaffR-Tall_bind domain-containing protein. (213 aa)
CD47CD47 glycoprotein isoform A. (317 aa)
CD9Tetraspanin. (224 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
SLC7A1AA_permease_C domain-containing protein. (624 aa)
RGCCRegulator of cell cycle. (135 aa)
TNFSF13BTNF family B cell activation factor; Belongs to the tumor necrosis factor family. (288 aa)
TNFRSF21Uncharacterized protein. (651 aa)
BLKTyrosine-protein kinase. (526 aa)
MFSD2BMajor facilitator superfamily domain containing 2B. (500 aa)
EPHA7Ephrin type-A receptor 7; Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repel [...] (993 aa)
CD80Uncharacterized protein. (316 aa)
NFKBIZANK_REP_REGION domain-containing protein. (618 aa)
SYKTyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] (636 aa)
CDH2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). (912 aa)
CD274Uncharacterized protein. (471 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (262 aa)
IL6STGlycoprotein 130. (918 aa)
PTPN2Uncharacterized protein. (597 aa)
CDH7Cadherin-7; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. (785 aa)
IL7RInterleukin-7 receptor alpha chain. (460 aa)
IL20RBInterleukin 20 receptor subunit beta. (312 aa)
BMP6Bone morphogenetic protein 6. (434 aa)
CG-1BBeta-galactoside-binding lectin; This protein binds beta-galactoside. May participate in host antiviral defense through specific interaction with glycans on the viral envelope glycoproteins. (135 aa)
AMHR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (678 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)
IGFBP2Insulin-like growth factor-binding protein 2; Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (311 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (671 aa)
IHHIndian hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP); Belongs to the hedgehog family. (408 aa)
IL12RB2Uncharacterized protein. (868 aa)
MYO10LUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2219 aa)
JAK1Tyrosine-protein kinase. (1150 aa)
GPNMBGlycoprotein nmb. (559 aa)
PLPP3acidPPc domain-containing protein. (313 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2119 aa)
MMRN1Multimerin 1. (1192 aa)
CXCL13L2Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (100 aa)
PAWRPro-apoptotic WT1 regulator. (337 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2036 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
FUT4Glyco_tran_10_N domain-containing protein. (356 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (203 aa)
ARG2Arginase. (356 aa)
DUSP10Uncharacterized protein. (478 aa)
FGGFibrinogen C-terminal domain-containing protein. (438 aa)
TMEM131LTransmembrane 131 like. (1719 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)
CD74Invariant chain isoform p41. (286 aa)
SIRPAUncharacterized protein. (381 aa)
CD83CD83 molecule. (215 aa)
VSIG4V-set and immunoglobulin domain containing 4. (389 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (667 aa)
CXCL13Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
NRARPNOTCH regulated ankyrin repeat protein. (124 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (741 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
CD28T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation. (304 aa)
CTLA4Cytotoxic T-lymphocyte-associated protein 4. (205 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
FGL2Fibrinogen C-terminal domain-containing protein. (439 aa)
HSPD160 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...] (573 aa)
CEBPBCCAAT/enhancer-binding protein beta; Important transcriptional activator regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'- T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG). Binds to the MGF and MIM-1 promoters and activates [...] (328 aa)
MAP2K5Uncharacterized protein. (582 aa)
NEXMIFNeurite extension and migration factor. (1454 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate; Belongs to the phosphoenolpyruvate carboxykinase [...] (622 aa)
FADDFas associated via death domain. (195 aa)
TFRCTransferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Belongs to the peptidase M28 family. M28B subfamily. (776 aa)
SOCS1Suppressor of cytokine signaling 1. (207 aa)
APOA1Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. (264 aa)
LOC771388Uncharacterized protein; Belongs to the glycosyltransferase 29 family. (384 aa)
GTPBP4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (631 aa)
CD81Tetraspanin. (237 aa)
CRTAMUncharacterized protein. (439 aa)
GLMNGlomulin, FKBP associated protein. (628 aa)
XBP1BZIP domain-containing protein. (372 aa)
ADIPOQC1q domain-containing protein. (244 aa)
SERPINE2SERPIN domain-containing protein; Belongs to the serpin family. (442 aa)
SH2B3SH2B adaptor protein 3. (539 aa)
LOC107052104Uncharacterized protein. (680 aa)
CARD11Uncharacterized protein. (1170 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (717 aa)
ABL1Tyrosine-protein kinase. (1111 aa)
ADAM19ADAM19. (900 aa)
CBFBUncharacterized protein. (187 aa)
DEF6DEF6 guanine nucleotide exchange factor. (625 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (699 aa)
CD276Uncharacterized protein. (314 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
CHST4Sulfotransferase; Belongs to the sulfotransferase 1 family. (379 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (175 aa)
LRRC32Uncharacterized protein. (708 aa)
SOX13SRY-box transcription factor 13. (666 aa)
LCKProto-oncogene tyrosine-protein kinase LCK; Tyrosine kinase that plays an essential role for the selection and maturation of developing T-cell in the thymus and in mature T-cell function. Is constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors and plays a key role in T-cell antigen receptor(TCR)-linked signal transduction pathways (By similarity); Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (508 aa)
DMAMHC class II M alpha chain. (263 aa)
LOC112531223Ig-like domain-containing protein. (164 aa)
FAM49BFamily with sequence similarity 49 member B. (324 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (214 aa)
DMTNAbLIM_anchor domain-containing protein. (687 aa)
ENSGALP00000065981TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (164 aa)
ENSGALP00000066004Ig-like domain-containing protein. (241 aa)
IL12RB1Fibronectin type-III domain-containing protein. (591 aa)
ENSGALP00000066325Uncharacterized protein. (71 aa)
BLAMHC_II_alpha domain-containing protein. (98 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (386 aa)
HHLA2HERV-H LTR-associating 2. (364 aa)
NCK1Cytoplasmic protein. (380 aa)
EFNB2Ephrin-B2; Belongs to the ephrin family. (333 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa)
CCL19C-C motif chemokine. (108 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSGALP00000068651Uncharacterized protein. (150 aa)
GATA3GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa)
FGL1Fibrinogen C-terminal domain-containing protein. (313 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (187 aa)
LOC101750889LRRCT domain-containing protein. (714 aa)
AKNAUncharacterized protein. (1246 aa)
RC3H1Ring finger and CCCH-type domains 1. (1114 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1416 aa)
TBX21T-box transcription factor 21. (580 aa)
PDCD1LG2Uncharacterized protein. (334 aa)
CD6Uncharacterized protein. (1081 aa)
RIPK3Uncharacterized protein. (424 aa)
ENSGALP00000071642SAM domain-containing protein. (136 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial polarization and the apical lumen formation during renal tubul [...] (589 aa)
NF2LFERM domain-containing protein. (648 aa)
SKAP1Src kinase associated phosphoprotein 1. (355 aa)
ENSGALP00000072274TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (126 aa)
LOC107057103Ig-like domain-containing protein. (271 aa)
FSTL3Follistatin like 3. (286 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (876 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (639 aa)
RHOHRas homolog family member H. (191 aa)
DHPSUncharacterized protein. (141 aa)
LOC112531109Uncharacterized protein. (128 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (766 aa)
ICOSIGv domain-containing protein. (232 aa)
ENSGALP00000073878Ig-like domain-containing protein. (276 aa)
CHIR-B2Uncharacterized protein. (322 aa)
LEF1HMG box domain-containing protein. (412 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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